HCMV Envelope Glycoprotein Diversity Demystified [PDF]
Frontiers in Microbiology, 2019 Human cytomegalovirus (HCMV) is the leading viral cause of congenital birth defects and is responsible for morbidity and mortality in immunosuppressed individuals.
Mathilde Foglierini +2 more
semanticscholar +5 more sources
US28: HCMV’s Swiss Army Knife [PDF]
Viruses, 2018 US28 is one of four G protein coupled receptors (GPCRs) encoded by human cytomegalovirus (HCMV). The US28 protein (pUS28) is a potent signaling molecule that alters a variety of cellular pathways that ultimately alter the host cell environment.
B. Krishna, W. Miller, C. O’Connor
semanticscholar +4 more sources
Human cytomegalovirus (HCMV) replication dynamics in HCMV-naive and -experienced immunocompromised hosts [PDF]
The Journal of Infectious Diseases, 2002 Human cytomegalovirus (HCMV) can infect both HCMV-naive and -experienced transplant patients. In this study, the growth rate of HCMV in HCMV-naive hosts (1.82 units/day; 95% confidence interval [CI], 1.44-2.56 units/day) was shown to be significantly ...
Burroughs, AK +3 more
core +6 more sources
HCMV Infection and Apoptosis: How Do Monocytes Survive HCMV Infection? [PDF]
Viruses, 2018 Human cytomegalovirus (HCMV) infection of peripheral blood monocytes plays a key role in the hematogenous dissemination of the virus to multiple organ systems following primary infection or reactivation of latent virus in the bone marrow.
Donna Collins-McMillen +6 more
semanticscholar +4 more sources
Humanes Cytomegalievirus (HCMV) [PDF]
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, 2017 Peer ...
Robert Koch-Institut
+6 more sources
Placental Extracellular Vesicles Exhibit Reduced Neurogenic Potential Linked to Changes in Their miRNA Landscape Upon HCMV Infection. [PDF]
J Extracell BiolABSTRACT Extracellular vesicles (EVs) are key mediators of maternal–foetal communication, regulating placental function and foetal development through the transfer of bioactive molecules. Although placental EVs play a crucial role in placental function during pregnancy, their contribution to foetal development, notably foetal brain, remains poorly ...
Martin C +12 more
europepmc +2 more sources
Association of human cytomegalovirus (HCMV) neutralizing antibodies with antibodies to the HCMV glycoprotein complexes [PDF]
Virology Journal, 2020 Abstract Background Human cytomegalovirus (HCMV) causes asymptomatic infections, but also causes congenital infections when women were infected with HCMV during pregnancy, and life-threatening diseases in immunocompromised patients.
Miho Shibamura +10 more
openalex +4 more sources
Human Cytomegalovirus Encoded miR-US25-1-5p Attenuates CD147/EMMPRIN-Mediated Early Antiviral Response. [PDF]
, 2017 Cellular receptor-mediated signaling pathways play critical roles during the initial immune response to Human Cytomegalovirus (HCMV) infection.
Chen, Huizi +6 more
core +8 more sources
Betaherpesvirus Incidence in Saliva Samples From Patients With Hematological Neoplasms: Frequency, Clinic and Diagnostic Insights. [PDF]
J Med VirolABSTRACT Hematological neoplasms (HN) are disorders originating in blood cells that hold significant epidemiological importance. Treatments available for these conditions can induce immunosuppression, and it increases the risk of viral infections and reactivations, mainly by Human betaherpesviruses (HCMV, HHV‐6, and HHV‐7).
Guimarães ACS +9 more
europepmc +2 more sources
HCMV Antivirals and Strategies to Target the Latent Reservoir
Viruses, 2021 Human cytomegalovirus (HCMV) is a ubiquitous human herpesvirus. In healthy people, primary infection is generally asymptomatic, and the virus can go on to establish lifelong latency in cells of the myeloid lineage.
Marianne R Perera, M. Wills, J. Sinclair
semanticscholar +1 more source