Results 41 to 50 of about 17,820 (185)

Coordination of NK cell markers expression and IgG response in hCMV infection

Медицинская иммунология, 2023
Human cytomegalovirus (hCMV) is a prevalent virus that affects a large proportion of the population worldwide. Natural Killer (NK) cells are essential immune cells that play a crucial role in controlling hCMV infection.
M. O. Ustiuzhanina, Ju. D. Vavilova, N. A. Alekseeva, G. V. Lutcenko, D. M. Chudakov, E. I. Kovalenko   +5 more
doaj   +1 more source

Herpesvirus and Adenotonsillar Hypertrophy in Chinese Children: An Epidemiological and Clinical Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To investigate the possible association between adenotonsillar hypertrophy (ATH) and herpesviral infections in children, and to examine correlations between specific viral detection and clinical characteristics. Methods We enrolled 43 children aged 3–14 years with ATH (mean age 76.56 ± 25.65 months; 31 boys).
Ting‐Ting Ji, Miao Fan, Dan Yu, Xin Ni, Xiao‐Dan Li, Xin‐Yu Wang, Lu Lu, Wen Su, Li‐Xing Tang, Wei Zhang, Xiao Xiao, Yang Han, Lin Mei, Sheng‐Cai Wang   +13 more
wiley   +1 more source

MECHANISMS OF IMMUNOLOGICAL TOLERANCE DISRUPTION

Transactions of the Karelian Research Centre of the Russian Academy of Sciences, 2016
Autoimmune diseases belong to disorders with an unclear etiology. The spectrum of autoimmune diseases is wide, the most well known of them are type 1 diabetes, rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, Crohn’s disease ...
Polina Kravchenko, Evgenia Oleinik
doaj   +1 more source

Olfactory Tuft Cells Are Critical to Basal Inflammation, Innate Immune Response to Viral Infection, and Modulation of Quiescent Stem Cell Activation, Proliferation and Differentiation

Cell Proliferation, EarlyView.
Olfactory tuft cells communicate with other mucosal cells in maintaining olfactory epithelial immunity and sensory function. Disruption of tuft cell signalling pathways causes a skewed immune response, leading to heightened inflammation and increased activation of the quiescent stem cells, which are further exacerbated by viral infection.
Sai‐Sai Zhang, Haiyan Wang, Yi‐Sen Yang, Yi‐Hong Li, Defu Yu, Yushi Yao, Ruhong Zhou, Liquan Huang   +7 more
wiley   +1 more source

Unmasking the Influence of Viral Micro‐RNAs on Host Immunity

Immunology &Cell Biology, EarlyView.
Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton, Bernadette M. Saunders   +1 more
wiley   +1 more source

Suppressive effects of pterostilbene on human cytomegalovirus (HCMV) infection and HCMV-induced cellular senescence

Virology Journal, 2022
Abstract Background Human cytomegalovirus (HCMV), a member of the β-herpesvirus family, causes the establishment of a latent infection that persists throughout the life of the host and can be reactivated when immunity is weakened.
Sanying Wang, Xuqiang Zhou, Xinyue He, Shushu Ma, Chuan Sun, Jing Zhang, Xiaogang Xu, Weihua Jin, Jin Yan, Ping Lin, Genxiang Mao   +10 more
openaire   +3 more sources

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

HCMV GrAbs a Mechanism to Escape Neutralization [PDF]

Cell Host & Microbe, 2011
The HCMV-neutralizing monoclonal antibody MSL-109 failed to prevent HCMV-induced disease in the clinic. In this issue of Cell Host & Microbe, Manley et al. (2011) found that MSL-109 rapidly induces antibody resistance by a nongenetic mechanism. Their results shed light on how antibodies can interact with their targets both outside and inside infected ...
Eisenberg, Roselyn J., Cairns, Tina M., Cohen, Gary H.   +2 more
openaire   +2 more sources

Identification and characterization of human cytomegalovirus-encoded circular RNAs

Frontiers in Cellular and Infection Microbiology, 2022
Circular RNA (circRNA) exists extensively and plays essential roles in serving as microRNA (miRNA) or protein sponges and protein scaffolding in many organisms.
Jingui Deng, Jingui Deng, Qing Wang, Jing Zhang, Jing Zhang, Jing Zhang, Yanping Ma, Yanping Ma, Ying Qi, Ying Qi, Ying Qi, Zhongyang Liu, Zhongyang Liu, Zhongyang Liu, Yibo Li, Yibo Li, Qiang Ruan, Qiang Ruan, Qiang Ruan, Yujing Huang, Yujing Huang, Yujing Huang   +21 more
doaj   +1 more source

Viruses, Periodontitis, and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte, Yvonne L. Hernandez‐Kapila, Henrik Dommisch   +2 more
wiley   +1 more source