Results 51 to 60 of about 17,820 (185)

Multiple Sclerosis and Viruses: « Liaisons Dangereuses »

Reviews in Medical Virology, Volume 36, Issue 6, November 2026.
ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Samanta Plavina, Daniela Malakovska, Jolanta Kalnina, Ilva Trapina, Elina Leonova, Mohammed Habib, Susanne Schifmann, Jegors Paramonovs, Nikolajs Sjakste, Yegor Vassetzky, Emmanuel Drouet, Natalia Paramonova   +11 more
wiley   +1 more source

The Viral Load of Human Cytomegalovirus Infection in Children following Hematopoietic Stem Cell Transplant by Chip Digital PCR

Canadian Journal of Infectious Diseases and Medical Microbiology, 2022
Objective. To detect viral load in human cytomegalovirus (HCMV) infection children after hematopoietic stem cell transplant (HSCT) by chip digital PCR (cdPCR). Methods.
Wen-Jun Wang, Miao Feng, Feng He, Juan Song, Qin-Qin Song, Dong Xia, Rong Liu, Hai-Lan Yao, Jun Han   +8 more
doaj   +1 more source

The Sleeping Giant: Metabolism and Autophagy in the Generation and Survival of Dormant Polyploid Giant Cancer Cells

MedComm, Volume 7, Issue 10, October 2026.
Polyploid giant cancer cells (PGCCs) arise in response to stress and play a critical role in therapy resistance and tumor dormancy. These cells can evade conventional treatments and later contribute to cancer relapse by generating progeny through nonmitotic, amitotic mechanisms.
Silvia Guil‐Luna, María Teresa Sánchez‐Montero, Alejandra Díaz‐Chacón, Antonio Rodríguez‐Ariza   +3 more
wiley   +1 more source

The microRNA Transcriptome of Human Cytomegalovirus (HCMV) [PDF]

The Open Virology Journal, 2012
The purpose of the present study was to characterize the microRNA transcriptome (miRNAome) of the human cytomegalovirus (HCMV or HHV5). We used deep sequencing and real time PCR (qPCR) together with bioinformatics to analyze the pattern of small RNA expression in cells infected with low-passage isolates of HCMV as well as in plasma and amniotic fluid ...
Meshesha, Mesfin K, Veksler-Lublinsky, Isana, Isakov, Ofer, Reichenstein, Irit, Shomron, Noam, Kedem, Klara, Ziv-Ukelson, Michal, Bentwich, Zvi, Avni, Yonat Shemer   +8 more
openaire   +2 more sources

Glutamine Metabolism in Health and Diseases

MedComm, Volume 7, Issue 10, October 2026.
Glutamine metabolism acts as a metabolic hub connecting cellular stress adaptation, immune regulation, and disease development. Through regulating energy production, biosynthesis, redox balance, and nitrogen metabolism, glutamine supports cellular homeostasis under physiological and pathological conditions.
Yi Ding, Fan Tong, Jing Zeng, Chun‐Ping Cui   +3 more
wiley   +1 more source

Evaluation of miR-101 and miR-122 Expression in Miscarriage Associated with Active Human Cytomegalovirus Infection: A Case-Control Study

Journal of Scientific Research in Science
Human cytomegalovirus is a common virus that infects a large proportion of the human population, particularly affecting the fetus during pregnancy. MicroRNAs (miRNAs) are essential post-transcriptional regulators of gene expression that play key roles in
Adnan Yaas Khudair , Rana Talib Jawad , Alyaa H. Alghrairi   +2 more
doaj   +1 more source

NKG2C+CD57+ Natural Killer Cell Expansion Parallels Cytomegalovirus-Specific CD8+ T Cell Evolution towards Senescence

Journal of Immunology Research, 2016
Objective. Measuring NKG2C+CD57+ natural killer (NK) cell expansion to investigate NK responses against human cytomegalovirus (HCMV) and assessing relationships with adaptive immunity against HCMV. Methods.
John Heath, Nicholas Newhook, Emilie Comeau, Maureen Gallant, Neva Fudge, Michael Grant   +5 more
doaj   +1 more source

Ovarian Cancer‐Associated Ascites Accumulates NK Lymphocytes Displaying a Transcriptomic Profile Consistent With the Immature/Secretory CD56bright Subtype

Immunology &Cell Biology, Volume 104, Issue 9, Page 896-905, October 2026.
NK cells present in EOC‐associated ascites retain elements of the conventional NK cell program while displaying a transcriptional profile distinct from peripheral blood NK cells. This profile encompasses biological programs usually associated with the CD56bright NK cell functions, which is consistent with transcriptional remodeling rather than complete
Caroline Natânia de Souza‐Araújo, Glenerson Baptista, Gabriela Rapozo Guimarães, Raissa Carolina Alves da Silva, Adriana Yoshida, Cláudia Rodrigues Tonetti, José Andrés Yunes, Daniela Maira Cardoso, Sophie Derchain, Mariana Boroni, Fernando Guimarães   +10 more
wiley   +1 more source

US28: HCMV’s Swiss Army Knife [PDF]

Viruses, 2018
US28 is one of four G protein coupled receptors (GPCRs) encoded by human cytomegalovirus (HCMV). The US28 protein (pUS28) is a potent signaling molecule that alters a variety of cellular pathways that ultimately alter the host cell environment. This viral GPCR is expressed not only in the context of lytic replication but also during viral latency ...
Krishna, Benjamin A, Miller, William E, O'Connor, Christine M   +2 more
openaire   +3 more sources

Association between cytomegalovirus infection, reduced gray matter volume, and resting-state functional hypoconnectivity in major depressive disorder: a replication and extension

Translational Psychiatry, 2021
Human cytomegalovirus (HCMV) is a neurotropic herpes virus known to cause neuropathology in patients with impaired immunity. Previously, we reported a reduction in the gray matter volume (GMV) of several brain regions in two independent samples of ...
Haixia Zheng, Bart N. Ford, Rayus Kuplicki, Kaiping Burrows, Peter W. Hunt, Jerzy Bodurka, T. Kent Teague, Michael R. Irwin, Robert H. Yolken, Martin P. Paulus, Jonathan Savitz   +10 more
doaj   +1 more source