Results 41 to 50 of about 46,134 (291)

Development of a Human Cytomegalovirus (HCMV)-Based Therapeutic Cancer Vaccine Uncovers a Previously Unsuspected Viral Block of MHC Class I Antigen Presentation [PDF]

, 2019
Human cytomegalovirus (HCMV) induces a uniquely high frequency of virus-specific effector/memory CD8+ T-cells, a phenomenon termed “memory inflation”.
Abate, Ahmed, Alexandrov, Alexandrov, Arnon, Avdic, Beyranvand Nejad, Brown, Brown, Browne, Chang, Chu, Cloughesy, Cobbs, Dasari, Dekhtiarenko, Del Val, Desjardins, Doisne, Dos Santos, Draper, Duhen, Dziurzynski, Engels, Fiallos, Filley, Fruh, Galluzzi, Gilbert, Gorzer, Harkins, Heemskerk, Howland, Jarry, Johnson, Jutz, Jutz, Kern, Klenerman, Korn, Kotenko, Lauvau, Le, Leisegang, Lim, Lockridge, Locy, Louveau, Lucas, Luo, Malouli, Martikainen, Mitchell, Mocarski, Nair, Neefjes, Odeberg, Overwijk, Pardieck, Polyzoidis, Potter, Prins, Pule, Raftery, Raftery, Raftery, Raftery, Rahman, Ratzinger, Reap, Reardon, Reed, Ressing, Riegler, Rizvi, Rosato, Rosskopf, Sampaio, Sampson, Sandalova, Schempp, Scheper, Schmolke, Schneider, Schonrich, Schub, Sckisel, Shah, Simoni, Sinzger, Soroceanu, Soroceanu, Strang, Stupp, Sturm, Sugawara, Sylwester, Thomas, Tischer, Tran, Trgovcich, Tumeh, van der Burg, van Willigen, Varnum, Vlahovic, Wen, Wills, Yan, Zhao   +109 more
core   +1 more source

Seroepidemiological Survey of Cytomegalovirus Infection among Pregnant Women in Sudan

Polish Journal of Microbiology, 2023
Human Cytomegalovirus (HCMV) is a leading healthcare problem associated with stillbirth and congenital abnormalities. Determining the seroprevalence and the possible risk factors related to HCMV infections may be a cornerstone in preventing its ...
Moglad Ehssan H., Hassan Ahmed O., Atta Elmanan Mawada S., Saeed Samar M., Abdalla Wafaa Mohammed, Mohammedsalih Kawthar Abdelgaleil, Ali Hatim T., Abd Elaziz Mohammed Siddig, Ahmed Hind Haidar   +8 more
doaj   +1 more source

Priming of NK cell anti-viral effector mechanisms by direct recognition of Human Cytomegalovirus

Frontiers in Immunology, 2013
NK cells play an important role in the defense against viral infections. Activation of resting NK cells is tightly controlled by the balance of surface inhibitory and activating receptors and aided by cytokines released by accessory cells along the anti ...
Aura eMuntasell, Marcel eCosta-Garcia, Andrea eVera, Noemi eMarina-Garcia, Carsten J Kirschning, Miguel eLópez-Botet, Miguel eLópez-Botet   +6 more
doaj   +1 more source

Altered serum human cytomegalovirus microRNA levels are common and closely associated with the inflammatory status in patients with fever

Frontiers in Immunology, 2022
BackgroundFever has a complicated etiology, and diagnosing its causative factor is clinically challenging. Human cytomegalovirus (HCMV) infection causes various diseases.
Cheng Wang, Cheng Wang, Yunhua Zhu, Yunhua Zhu, Penglu Chen, Penglu Chen, Chen Wang, Wanqing Zhou, Wanqing Zhou, Cuiping Zhang, Jing Wang, Xi Chen, Meng Ding, Meng Ding, Chunni Zhang, Chunni Zhang, Jun-Jun Wang, Chen-Yu Zhang, Chen-Yu Zhang   +18 more
doaj   +1 more source

A Very Strong Enhancer Is Located Upstream of an Immediate Early Gene of Human Cytomegalovirus [PDF]

, 1985
A strong transcription enhancer was identified in the genomic DNA (235 kb) of human cytomegalovirus (HCMV), a ubiquitous and severe pathogen of the herpesvirus group.
Boshart, Michael, Dorsch-Häsler, Karoline, Fleckenstein, Bernhard, Jahn, Gerhard, Schaffner, Walter, Weber, Frank   +5 more
core   +1 more source

Primary Human Cytomegalovirus (HCMV) Infection in Pregnancy. [PDF]

Deutsches Ärzteblatt international, 2017
In 0.5-4% of pregnancies, the prospective mother sustains a primary infection with human cytomegalovirus (HCMV). An HCMV infection of the fetus in the first or second trimester can cause complex post-encephalitic impairment of the infant brain, leading to motor and mental retardation, cerebral palsy, epilepsy, retinal defects, and progressive hearing ...
H. Buxmann, K. Hamprecht, M. Meyer-Wittkopf, K. Friese   +3 more
semanticscholar   +3 more sources

HCMV Assembly Is Totally Tubular [PDF]

Developmental Cell, 2018
Microtubules are normally organized at centrosomes, but other sites can also serve as microtubule organizing centers (MTOCs). In this issue of Developmental Cell, Procter et al. (2018) show that the human cytomegalovirus virion assembly compartment acts as a dynamic Golgi-derived MTOC where EB3 nucleates microtubules and regulates infectious virion ...
Shelby M, Lyon, Robert F, Kalejta
openaire   +2 more sources

RNA-binding protein CPEB1 remodels host and viral RNA landscapes. [PDF]

, 2016
Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in
Aigner, Stefan, Ares, Manuel, Batra, Ranjan, Belzile, Jean-Philippe, Bos, Tomas J, Clark, Elizabeth, Donohue, John Paul, Gelboin-Burkhart, Chelsea, Huang, Hui, Huelga, Stephanie C, Rigo, Frank, Roberts, Brett T, Sathe, Shashank, Spector, Deborah H, Stark, Thomas J, Wheeler, Emily C, Yee, Brian A, Yeo, Gene W   +17 more
core   +2 more sources

Activating KIRs and NKG2C in viral infections: towards NK cell memory?

Frontiers in Immunology, 2015
Natural Killer cells are important players in the immune defence against viral infections. The contribution of activating Killer Immunoglobulin-like Receptors (KIRs) and CD94/NKG2C in regulating anti-viral responses has recently emerged.
Mariella eDella Chiesa, Simona eSivori, Simona eCarlomagno, Lorenzo eMoretta, Alessandro eMoretta   +4 more
doaj   +1 more source

Circulating cytokine and chemokine patterns associated with cytomegalovirus reactivation after stem cell transplantation

Clinical & Translational Immunology, 2023
Objectives Human cytomegalovirus (HCMV) reactivation is the leading viral complication after allogeneic haematopoietic stem cell transplantation (allo‐HSCT).
Lauren Stern, Helen M McGuire, Selmir Avdic, Emily Blyth, David Gottlieb, Ellis Patrick, Allison Abendroth, Barry Slobedman   +7 more
doaj   +1 more source