Results 51 to 60 of about 44,631 (298)
Translational Psychiatry, 2021 Human cytomegalovirus (HCMV) is a neurotropic herpes virus known to cause neuropathology in patients with impaired immunity. Previously, we reported a reduction in the gray matter volume (GMV) of several brain regions in two independent samples of ...
Haixia Zheng +10 more
doaj +1 more source
Characterization of the murine cytomegalovirus genes encoding the major DNA binding protein and the ICP18.5 homolog [PDF]
, 1992 In several herpesviruses the genes for the major DNA binding protein (MDBP), a putative assembly protein, the glycoprotein B (gB), and the viral DNA polymerase (pol) coliocate.
Keil, Günther M. +3 more
core +1 more source
Phase 2 Study of Anti-Human Cytomegalovirus Monoclonal Antibodies for Prophylaxis in Hematopoietic Cell Transplantation. [PDF]
, 2020 Human cytomegalovirus (HCMV) can cause significant disease in immunocompromised patients, and treatment options are limited by toxicities. CSJ148 is a combination of two anti-HCMV human monoclonal antibodies (LJP538 and LJP539) that bind to and inhibit ...
Akard, Luke +22 more
core +3 more sources
Cancers, 2019 Previously recognized classical human onco-viruses can regulate complex neoplastic events, and are estimated to play a role during carcinogenesis in 15–20% of cancer cases.
J. Geisler +4 more
semanticscholar +1 more source
RNA-binding protein CPEB1 remodels host and viral RNA landscapes. [PDF]
, 2016 Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in
Aigner, Stefan +17 more
core +2 more sources
Battle between Host Immune Cellular Responses and HCMV Immune Evasion
International Journal of Molecular Sciences, 2019 Human cytomegalovirus (HCMV) is ubiquitously prevalent. HCMV infection is typically asymptomatic and controlled by the immune system in healthy individuals, yet HCMV can be severely pathogenic for the fetus during pregnancy and in immunocompromised ...
T. Manandhar +4 more
semanticscholar +1 more source
A Viral Pilot for HCMV Navigation? [PDF]
Viruses, 2015 gH/gL virion envelope glycoprotein complexes of herpesviruses serve as entry complexes and mediate viral cell tropism. By binding additional viral proteins, gH/gL forms multimeric complexes which bind to specific host cell receptors. Both Epstein–Barr virus (EBV) and human cytomegalovirus (HCMV) express alternative multimeric gH/gL complexes.
openaire +3 more sources
The microRNA Transcriptome of Human Cytomegalovirus (HCMV) [PDF]
The Open Virology Journal, 2012 The purpose of the present study was to characterize the microRNA transcriptome (miRNAome) of the human cytomegalovirus (HCMV or HHV5). We used deep sequencing and real time PCR (qPCR) together with bioinformatics to analyze the pattern of small RNA expression in cells infected with low-passage isolates of HCMV as well as in plasma and amniotic fluid ...
Zvi Bentwich +8 more
openaire +3 more sources
Reduced progression of bone erosion in cytomegalovirus seropositive rheumatoid arthritis patients
Arthritis Research & Therapy, 2020 Background Human cytomegalovirus (HCMV) seropositivity has been associated with higher inflammation during rheumatoid arthritis (RA). However, no data are available on the impact of HCMV seropositivity on bone erosion progression during RA.
B. Rauwel +10 more
doaj +1 more source
NK cells expansion in vitro is followed by loss of inhibitory KIR expression
Медицинская иммунология, 2023 NK cells are innate lymphocytes that are able to eliminate altered cells, which makes them promising for the immunotherapy of viral diseases and tumors. The NK cell population is characterized by high phenotypic and functional diversity.
N. A. Alekseeva +5 more
doaj +1 more source