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Apoptotic effect of Naphthoquinone derivatives on HCT116 colon cancer cells

Genes & Genomics, 2010
Naphthoquinone is found in the core structure of many natural compounds, most notably the K vitamins. Numerous molecules with the 1,4-naphthoquinone moiety are known to display distinct biological activities including anti-cancer, anti-inflammatory and anti-bacterial activities.
Young-Sam Im   +9 more
openaire   +1 more source

Increased PKN2 and M2-Polarized Macrophages Promote HCT116 Cell Invasion

Critical Reviews in Immunology
Colorectal cancer is the third most common malignant tumor, with highly invasive and metastatic potential in the later stage. This study investigated the role of PKN2 overexpression and M2-polarized macrophages in dictating the malignant phenotype of colorectal cancer cells.
Cheng, He   +3 more
openaire   +2 more sources

Effect of coumarin and diallyl polysulfides on HCT116 colon cancer cells

2014
Polysulfane sind Inhaltsstoffe des Knoblauchs, die als potentielle pharmakologisch wirksame Verbindungen betrachtet werden, da sie sich als Hemmstoffe des Krebszellwachstums herauskristallisiert haben. Zahlreiche Aspekte dieser Hemmung sind noch unklar.
openaire   +1 more source

Apigenin rich-Limonium duriusculum (de Girard) Kuntze promotes apoptosis in HCT116 cancer cells

Natural Product Research, 2021
Pamela Gatto   +2 more
exaly  

p14ARF re-expression induces apoptosis in aneuploid HCT116 cells

2012
Weakening the Spindle Assembly Checkpoint by reduced expression of its components such as MAD2, BubR1 and MPS1 induces chromosome instability and aneuploidy both hallmarks of cancer cells. p14ARF that is found frequently altered in human cancers, is overexpressed in response to oncogenic stimuli to stabilize p53 halting cell progression. Previously, we
VENEZIANO, Lorena   +2 more
openaire   +1 more source

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