Exploring the apoptotic effects of sericin on HCT116 cells through comprehensive nanostring transcriptomics and proteomics analysis. [PDF]
Sci RepRatanabunyong S +7 more
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Domperidone, a Dopamine Receptor D2 Antagonist, Induces Apoptosis by Inhibiting the ERK/STAT3-Mediated Pathway in Human Colon Cancer HCT116 Cells. [PDF]
Biomol Ther (Seoul)Sim SJ, Jang JH, Choi JS, Chun KS.
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Differential lipid analysis of oxaliplatin-sensitive and resistant HCT116 cells reveals different levels of drug-induced lipid droplet formation. [PDF]
Anal Bioanal ChemLarson TS +3 more
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Responsive ZIF-90 nanocomposite material: targeted delivery of 10-hydroxycamptothecine to enhance the therapeutic effect of colon cancer (HCT116) cells. [PDF]
RSC Med ChemGuo JC +9 more
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Cell shape instability during cytokinesis in tetraploid HCT116 cells
Biochemical and Biophysical Research Communications, 2023Tetraploidy is a hallmark of broad cancer types, but it remains largely unknown which aspects of cellular processes are influenced by tetraploidization in human cells. Here, we found that tetraploid HCT116 cells manifested severe cell shape instability during cytokinesis, unlike their diploid counterparts.
Takahiro, Yamamoto, Ryota, Uehara
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SUMMARY Bax is a very important pro‐apoptosis molecule. HCT116/Bax−/– cells do not express the pro‐apoptosis Bcl‐2 family member, Bax. In the present study, the anticancer effects of gossypol on HCT116 and HCT116/Bax−/– cells were compared in terms of inhibition of cell growth, inhibition of colony formation and induction of apoptosis.
Manchao, Zhang +5 more
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The involvement of ROS generation on Epoxiconazole-induced toxicity in HCT116 cells
Pesticide Biochemistry and Physiology, 2018Abstract Triazole fungicides are the most efficient class of pesticides and have been in rapid development since the 1970s, receiving worldwide recognition. Epoxiconazole is a systemic fungicide belonging to the most widely used members of triazole group and its environmental residue in water has been detected at concentrations up to 7.7 g/l [1 ...
Hiba, Hamdi +4 more
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Biphasic Regulation of Cell Death and Survival by Hydrophobic Bile Acids in HCT116 Cells
Nutrition and Cancer, 2009A secondary bile acid, namely, deoxycholic acid (DCA), has been known to promote colon tumors; on the other hand, it also induces apoptosis in several human colon cancer cell lines. A hydrophobic primary bile acid, namely, chenodeoxycholic acid (CDCA), exhibits a similar property of apoptosis induction; DCA and CDCA also trigger some specific ...
Satoko, Yui +2 more
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Characterization of HCT116 Human Colon Cancer Cells in an Orthotopic Model
Journal of Surgical Research, 2008Colorectal cancer metastases result in a significant number of cancer related deaths. The molecular mechanisms underlying this complex, multi-step pathway are yet to be completely elucidated. In the absence of any transgenic models of colon cancer metastases, an in vivo model system that fulfills the rate limiting steps of metastasis (local invasion ...
Ashwani, Rajput +9 more
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