Butyrate-mediated Resistance to Trichostatin A Accompanied by Elevated Expression of Glucose Transporter 3 (GLUT3) in Human Colorectal Carcinoma HCT116 Cells. [PDF]
Asian Pac J Cancer Prev, 2023 Khonthun C, Surangkul D.
europepmc +1 more source
Phenotypic profiling of small molecules using cell painting assay in HCT116 colorectal cancer cells
PLOS OneUnderstanding how small molecules affect cellular morphology is essential for exploring their mechanisms of action (MoA) and identifying new therapeutic candidates. In this study, the Cell Painting Assay (CPA) was used to profile 196 small molecules in HCT116 colorectal cancer cells.
Velemir Lavrinenko +5 more
openaire +2 more sources
Chromosome counts in parental and STAG2 mutant HCT116 cells.
, 2016 Chromosome counts in parental and STAG2 mutant HCT116 cells.
Jan-Michael Peters (32990) +7 more
core
Effect of curcumin and/or 5-FU on apoptosis in HCT116 and HCT116+ch3 colon cancer cells.
, 2013 HCT116 and HCT116+ch3 cells were treated with different concentrations of curcumin or 5-FU (0, 1, 5, 10 and 20 µM) or a combination of curcumin (5 µM) and 5-FU (0.1, 1, 2 and 3 µM) for 24 h.
Ajay Goel (130080) +5 more
core +1 more source
Cancer Science, EarlyView.Mice expressing only mutant PTEN Y138L, a protein which shows normal suppression of cellular AKT yet lacks protein phosphatase activity, die in utero, and heterozygous mice display a range of tumors. This indicates both the lipid and protein phosphatase activities of PTEN work together for normal tumor suppression and embryonic development.
Priyanka Tibarewal +16 more
wiley +1 more source
Erratum: [Corrigendum] Effects of histone deacetylase inhibitors on ATP‑binding cassette transporters in lung cancer A549 and colorectal cancer HCT116 cells. [PDF]
Oncol Lett, 2023 Wang H +5 more
europepmc +1 more source
Effects of TPP1 overexpression on the radiosensitivity and cell cycle in HCT116 cells.
, 2013 (A)Verification of TPP1 overexpression by western blotting. (B) HCT116-Mock and-TPP1 cells were irradiated with X-rays and then cell survival was determined using clonogenic assay.
Wenbo Wang (300277) +12 more
core +1 more source
Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy
Cancer Science, EarlyView.This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang +6 more
wiley +1 more source
Borylcyclopropanes: Synthetic Strategies and Applications
Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley +2 more sources
Gallium Metal-Organic Nanoparticles with Albumin-Stabilized and Loaded Graphene for Enhanced Delivery to HCT116 Cells. [PDF]
Int J Nanomedicine, 2023 Wu YY +8 more
europepmc +1 more source