Results 151 to 160 of about 47,486 (225)

The tumor suppressive effect and apoptotic mechanism of TRAIL gene-containing recombinant NDV in TRAIL-resistant colorectal cancer HT-29 cells and TRAIL-nonresistant HCT116 cells, with each cell bearing a mouse model. [PDF]

Cancer Med, 2023
Jung BK, An YH, Jang SH, Ryu G, Jung SB, Kim S, Kim CS, Jang H.   +7 more
europepmc   +1 more source

Decoding the Oncogenic Role of GNG10 in Colorectal Cancer: A Non‐Canonical Wnt Pathway–Driven Mechanism

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Guanine nucleotide‐binding protein gamma 10 (GNG10) is implicated in various biological processes, yet its specific oncogenic role in colorectal cancer (CRC) remains poorly defined. This study aimed to elucidate the expression patterns, biological functions, and underlying mechanisms of GNG10 in CRC progression.
Xitao Zhang, Yuting Tang, Xuexiao Li, Ou Li, Yaoqian Liu, Jianping He, Tianlai Liu   +6 more
wiley   +1 more source

Synthesis, Characterization and Anticancer Efficacy Studies of Iridium (III) Polypyridyl Complexes against Colon Cancer HCT116 Cells. [PDF]

Molecules, 2022
Xie B, Wang Y, Wang D, Xue X, Nie Y.
europepmc   +1 more source

PTTG2 Silencing results in loss of cell adhesion and apoptosis in adenocarcinoma HCT116 cells

, 2011
1 página. XIV Congresos de la Sociedad Española de Biología Celular (Málaga, 12-15 de diciembre, 2011)
Gámez del Estal, María del Mar, Méndez-Vidal, Cristina, Pintor-Toro, José Antonio   +2 more
openaire   +1 more source

Therapeutic Potential of Cucurbitacin I in Colon Adenocarcinoma Is Mediated by Modulation of SDHA Expression

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Colorectal cancer is a prevalent malignancy, with colon adenocarcinoma (COAD) representing its most common histological subtype. Although most stage I patients remain disease‐free after treatment, a subset rapidly progresses to advanced disease with markedly reduced survival.
Danni Zhao, Xunzhi Zhang, Wenke Xiao, Yue Lin, Zhixiang Wu, Xinyu Tang, Qian Cheng, Pengmian Feng, Wei Chen   +8 more
wiley   +1 more source

CRISPR/Cas9-mediated claudin-2 knockout in HCT116 cells reveals its key role in colorectal cancer progression. [PDF]

Oncol Lett
Alghamdi RA, Al-Zahrani MH.
europepmc   +1 more source

Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells. [PDF]

FEBS Open Bio, 2022
Uchenunu O, Zhdanov AV, Hutton P, Jovanovic P, Wang Y, Andreev DE, Hulea L, Papadopoli DJ, Avizonis D, Baranov PV, Pollak MN, Papkovsky DB, Topisirovic I.   +12 more
europepmc   +1 more source

RNA Metabolism Genes as Prognostic Biomarkers and Therapeutic Targets in Colorectal Cancer Based on the Analysis of Single‐Cell and Bulk‐RNA Sequencing Data

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Colorectal cancer (CRC) is one of the most common malignancies worldwide and remains a major cause of cancer‐related mortality. Increasing evidence suggests that aberrant RNA metabolism contributes to tumour initiation, progression and therapeutic resistance.
Fandong Kong, Xuewei Zhang, Shuguang Su, Feilong Chen, Qiantao Ye, Ronghua Yang, Hanpeng Du   +6 more
wiley   +1 more source

Transcriptomic and Cytogenetic Analysis of Oxaliplatin-Resistant Colorectal Adenocarcinoma HCT116 Cells to Identify Markers Associated with Platinum Resistance. [PDF]

Int J Mol Sci
Morshneva A, Gnedina O, Fedotova K, Yartseva N, Aksenov N, Igotti M.   +5 more
europepmc   +1 more source

Sorafenib, rapamycin, and venetoclax attenuate doxorubicin-induced senescence and promote apoptosis in HCT116 cells. [PDF]

Saudi Pharm J, 2022
As Sobeai HM, Alohaydib M, Alhoshani AR, Alhazzani K, Almutairi MM, Saleh T, Gewirtz DA, Alotiabi MR.   +7 more
europepmc   +1 more source