Results 151 to 160 of about 4,460,555 (293)
Apoptosis analysis induced by 1d in HCT116 cells.
, 2015 (A) Representative plots of flow cytometry analyses of HCT116 cells treated with 1d or DMSO (control) for 24 h followed by Annexin V-FITC and PI staining. (B) The percentage of apoptotic cells in the above analysis.
Yunyun Geng (749765) +9 more
core +1 more source
Harnessing the Folding of Antitumor Peptides for Controlled Carrier‐Free Drug Delivery
Small, EarlyView.A disulfide‐bridged stapled p53 α‐helix co‐assembled with doxorubicin into protease‐resistant nanocomplexes. Reductive intracellular conditions induced helix refolding and nanostructure disassembly, which enabled the coordinated release of the chemotherapeutic agent and anticancer peptide.
Jae Yun Lee +9 more
wiley +1 more source
Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments
Smart Molecules, EarlyView.Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu +7 more
wiley +1 more source
Macrophage-derived factors do not protect HCT116WT cells from TRAIL induced apoptosis.
, 2013 A: Parental HCT116 cells or HCT116 with deleted WT or MT β-catenin allele were treated with TRAIL in the absence of THP1 macrophages or IL1 as indicated. B: The extent of apoptosis was determined in 4 independent experiments.
Pawan Kaler (245401) +2 more
core +1 more source
Smart Molecules, EarlyView.We developed a lipophilic near‑infrared probe (DCIP‑AcGal) that is specifically activated by senescence‑associated β‑galactosidase. After intravenous injection, it lights up therapy‑induced tumor senescence in living mice. Its optimized lipophilicity also enables blood‑brain barrier crossing to detect natural brain senescence ex vivo. This probe offers
Jiani Huang +15 more
wiley +1 more source
Apoptosis Induction in HepG2 and HCT116 Cells by a Novel Quercetin-Zinc (II) Complex: Enhanced Absorption of Quercetin and Zinc (II). [PDF]
Int J Mol Sci, 2023 Nakamura M +5 more
europepmc +1 more source
The Changes of Expression of Survivin by Butyrate in HCT116 Colon Cancer Cells
Journal of the Korean Surgical Society, 2009 Purpose: The causes of colon cancer can be divided into genetic and environmental components. A high-fiber diet is known to reduce the risk of colon cancer. Dietary fiber is converted to short chain fatty acid, butyrate, in the colon by bacteria. Butyrate is used as an energy source for the colonic epithelial cells, and is known to induce apoptosis in ...
openaire +1 more source
British Journal of Pharmacology, EarlyView.Extracellular vesicles (EVs) are a diverse population of membrane nanoparticles secreted by nearly all cell types, playing a key role in intercellular communication by transferring bioactive macromolecular cargo. In cancer, EVs shape both the local tumour microenvironment and distant premetastatic niches.
Evangelia Pantazaka +3 more
wiley +1 more source
Feedback Modulation between Human INO80 Chromatin Remodeling Complex and miR-372 in HCT116 Cells. [PDF]
Int J Mol Sci, 2023 Shah JA +8 more
europepmc +1 more source
British Journal of Pharmacology, EarlyView.Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff +3 more
wiley +1 more source