Results 141 to 150 of about 4,460,555 (293)
iMetaMed, EarlyView.Schematic illustration of the preparation of His@PDA@Needle, a modified acupuncture needle designed for minimally invasive sampling of lymph node‐derived DNA for molecular profiling. ABSTRACT Current clinical liquid biopsy approaches predominantly rely on blood‐derived biomarkers, which are often limited in sensitivity.
Baiping Cui +5 more
wiley +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Oxaliplatin is a platinum‐based anticancer agent widely used for gastrointestinal malignancies; however, it is known to cause dose‐dependent peripheral neuropathy (OIPN), a characteristic adverse effect. OIPN results in a reduced quality of life and often necessitates dose reduction or discontinuation of oxaliplatin; however, effective ...
Yusuke Koura +11 more
wiley +1 more source
Localization of phospho-PKR and total-PKR in HCT116 p53+/+ and HCT116 p53−/− cells.
, 2013 (A) HCT116 p53+/+ cells and (B) HCT116 p53−/− cells were mock treated or treated with 5 µM of 5-FU. At the indicated times cells were fixed and processed for immunofluorescence analysis by confocal microscopy as described in Material and Methods using ...
Jose Carlos Prados (345573) +10 more
core +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT This study highlights the potential use of Cotinus coggygria Scop. plant extract in a single‐step synthesis of biocompatible and ultrasmall AgNPs for in vitro applications. Herein, microscopic analyses revealed that AgNP exposure did not induce appreciable morphological changes in CRL‐4010 cells, whereas MCF‐7 and MDA‐MB‐231 cells exhibited ...
Ümran Ünüvar +3 more
wiley +1 more source
BMC CancerBackground Colorectal cancer (CRC) is a common gastrointestinal cancer, and even though oxaliplatin chemotherapy is effective, there is a high likelihood of relapse, indicating the presence of oxaliplatin-resistant CRC.
Hoda Deli +5 more
doaj +1 more source
Hematological parameters of nude mice injected with HCT116 cells.
, 2015 Hematological parameters of nude mice injected with HCT116 cells.
Fanni Li (533363) +7 more
core +1 more source
Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security
Journal of the Science of Food and Agriculture, EarlyView.Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori +9 more
wiley +1 more source
The Journal of Pathology, EarlyView.Abstract The progression of colorectal cancer (CRC) is critically regulated by cancer‐associated fibroblasts (CAFs) within the tumor microenvironment (TME), yet the specific molecular mechanisms by which CAFs influence CRC remain unclear. This study reveals the mechanism by which CAFs promote CRC malignant progression and immune suppression through ...
Huachi Li +6 more
wiley +1 more source
Effects of KU-55933 on HCT116 p53+/+ and HCT116 p53−/− cells.
, 2012 Cells were seeded into 96-well plates with 10% FBS and after 24 hrs. exposed to KU-55933 (10 µM) or metformin (5 mM) in DMEM containing 1% FBS for 72 hrs. (A) Cell growth was estimated by Alamar Blue dye reduction.
Julie St Pierre (118437) +6 more
core +1 more source
Phytotherapy Research, EarlyView.Schisandrin C: A Dual Anti‐Colorectal Cancer Strategy Targeting PPARγ. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer mortality, necessitating novel therapeutic strategies. Schisandrin C (SinC), a bioactive lignan from Schisandra chinensis, exhibits diverse pharmacological activities, but its anti‐CRC mechanisms are poorly ...
Xiao Wei +4 more
wiley +1 more source