Results 141 to 150 of about 47,486 (225)

Microarray dataset supporting a role for ATF4 in isoginkgetin-induced gene expression in HCT116 cells. [PDF]

Data Brief, 2022
van Zyl E, Tolls V, McKay BC.
europepmc   +1 more source

Stearoyl‐CoA Desaturase‐1 Drives Tumor Growth by Interacting With Histone Deacetylase‐2 and Deacetylating Nucleophosmin‐1

MedComm, Volume 7, Issue 6, June 2026.
Hypoxia induces SCD1 and PLIN2 to drive lipid droplet‐dependent metabolic adaptation in cancer cells. PLIN2 supports survival under stress, whereas SCD1 promotes proliferation upon reoxygenation and remodels the acetylome via HDAC2‐mediated NPM1 deacetylation and destabilization.
Coline Wery, Laetitia Montero‐Ruiz, Eric Bonneil, Mohammad Farran, Robin Jehay, Quentin Herrara Garfia, Gregory Fettweis, Silvia Blacher, Charles Pottier, Gael Cobraiville, Yasmine Boumahd, Olivier Peulen, Agnès Noël, Franck Dequiedt, Marianne Fillet, Nor Eddine Sounni   +15 more
wiley   +1 more source

The Machnism of XIAP and TRAIL Resistance in HCT116 bax-/-

四川大学学报. 自然科学版, 2016
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is one of the members of the tumor necrosis factor (TNF) superfamily. It can activate the apoptosis signaling pathways through engagement of the specific death receptors (DR4) or (DR5) in a ...
LONG Tian-Zhen, HUANG Xue-Qin, LIU Hai-Peng, FENG Hai-Yan, XU Yang, LIANG Peng   +5 more
doaj  

Expressing MLH1 in HCT116 cells increases cellular resistance to radiation by activating the PRKAC. [PDF]

Exp Biol Med (Maywood), 2022
Huang Y, Feng L, Bao Y, Zhang Y, Liang J, Mao Q, Li J, Jiang C.   +7 more
europepmc   +1 more source

Synthesis, Photophysical Characterization, and Anticancer Evaluation of Novel Furochromene Derivatives

ChemistryOpen, Volume 15, Issue 6, June 2026.
This is the first study on novel furochromene derivatives. A series of novel furochromen derivatives, namely (2E)‐1‐(6‐hydroxy‐4,7‐dimethoxy‐1‐benzofuran‐5‐yl)‐3‐arylprop‐2‐en‐1‐ones 4a–c, were synthesized via the Knoevenagel condensation of 6‐hydroxy‐4,7‐dimethoxybenzofuran‐5‐ylethanone 2 with various aromatic aldehydes.
Amal Rabahi, Mustapha Mounir Bouhenna, Hasnia Abdeldjebar, Massinissa Baymout, Malika Makhloufi‐Chebli, Walter Luyten, Hamdi Bendif, Anis Ahmad Chaudhary, Walid Elfalleh, Stefania Garzoli   +9 more
wiley   +1 more source

Comparative Mechanistic Insights into Quercetin-Loaded Selenium Nanoparticles and Cisplatin in HCT116 Cells. [PDF]

ACS Omega
Alsubaie S, Merghani N, Abudawood M, Siddiqi NJ, Fatima S.   +4 more
europepmc   +1 more source

Proanthocyanidin oligomers extract from hawthorn mediates cell cycle arrest, apoptosis, and lysosome vacuolation on HCT116 cells. [PDF]

Curr Res Food Sci, 2022
Sun YS, Wang ZW, Gao Z, Zhao W, Thakur K, Zhong Q, Wei ZJ.   +6 more
europepmc   +1 more source

Kineochelins—A New Group of Siderophores From an Antarctic Bacterium

Microbial Biotechnology, Volume 19, Issue 6, June 2026.
Genome‐guided analysis of an Antarctic Actinokineospora strain led to the discovery of kineochelins, a new group of siderophores involved in iron sequestration and microbial competition. Kineochelin production inhibits co‐occurring bacteria and clinically relevant yeasts, highlighting Antarctic microorganisms as promising sources of bioactive natural ...
Stanislava Kralova, Peter Spacek, Johannes Gafriller, Matej Bezdicek, Viktoria Medvedcova, Joana Séneca, Jay Osvatic, Ulrike Grienke, Thomas Rattei, Olga N. Sekurova, Sergey B. Zotchev, Martin Zehl, Alexander Loy   +12 more
wiley   +1 more source

Discovery of a Novel γ‐Glutamylcyclotransferase Inhibitor Plumbagin by Luminescence‐Based High‐Throughput Screening

Cancer Science, Volume 117, Issue 6, Page 1713-1723, June 2026.
A cell‐based high‐throughput screening system utilizing the luminescent probe LISA‐103 was developed to monitor γ‐glutamylcyclotransferase (GGCT) activity in cancer cells. Through this assay, plumbagin was identified as a novel GGCT inhibitor that induces cell cycle arrest and suppresses cancer cell growth. ABSTRACT γ‐Glutamylcyclotransferase (GGCT) is
Keiko Taniguchi, Yukie Nohara, Mano Horinaka, Kozue Nose, Masaya Mori, Hiromi Ii, Hiroko Kawakami, Kazuto Yano, Susumu Nakata, Taku Yoshiya, Toshiyuki Sakai   +10 more
wiley   +1 more source

Deactivation of CK1α enhances the anti-cancer effects of salinomycin in colorectal cancer HCT116 cells. [PDF]

Biochem Biophys Rep
Khakshournia S, Siri M, Zamani M, Bozorg-Ghalati F, Mojtahedi Z, Igder S, Azarpira N, Mokarram P.   +7 more
europepmc   +1 more source