Results 131 to 140 of about 4,460,555 (293)
DNA damage activates p38 MAPK in HCT116 cells.
, 2013 A) HCT116 cells were left untreated or irradiated (20 Gy) and further incubated in complete medium for 3h. Samples were subjected to western blot analysis as described in Figure 5A.
Lina Guerra (85942) +6 more
core +1 more source
BMEMat, EarlyView.This review highlights critical “translational gaps” in understanding micro‐ and nanoplastics impacts on gastrointestinal diseases, bridging exposure, detecting, and mechanistic toxicology. Abstract Micro‐ and nanoplastics (MNPs) have become pervasive environmental contaminants with increasing evidence linking them to adverse health outcomes.
Zhenli Diao +3 more
wiley +1 more source
1d-induced apoptosis in HCT116 cells is partially dependent on p53.
, 2015 (A) HCT116 (p53+/+) and HCT116-p53-/- cells were treated with 1 μg/ml of 1d or DMSO (control) for the indicated time periods and then stained with crystal violet.
Yunyun Geng (749765) +9 more
core +1 more source
Chemistry – A European Journal, EarlyView.Tris(indol‐3‐yl)methanes were synthesized from indoles, CO2, and PhMe2SiH in the presence of BPh3 in acetonitrile at 50°C. One product, tris(4‐bromo‐1‐methylindol‐3‐yl)methane, underwent a palladium‐catalyzed cascade reaction for the formation of a novel polycyclic heteroaromatic compound, where the methine C(sp3) atom originating from CO2 was ...
Sha Li +5 more
wiley +1 more source
TNFα induces migration and invasion of HCT116 cells.
, 2013 (A) HCT116 cells were allowed to migrate transwell chambers for 24 h in the presence or absence of TNFα (20 ng/ml). After 24 h, the migrated cells were fixed, stained, and photographed. Magnification, 100×. (B) The number of migrated cells.
Shao-Hui Cai (335225) +9 more
core +1 more source
Secretopathies emerge as a new class of neurocristopathies
Developmental Dynamics, EarlyView.Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira +3 more
wiley +1 more source
Stabilization of P/CAF, as a ubiquitin ligase toward MDM2, suppresses mitotic cell death through p53-p21 activation in HCT116 cells with SIRT2 suppression [PDF]
We previously reported that the suppression of SIRT2, an NAD + -dependent protein deacetylases, induces p53 accumulation via degradation of p300 and the subsequent MDM2 degradation, eventually leading to apoptosis in HeLa cells.
80305573 +13 more
core +1 more source
Effective knockdown of B7-H1 by siRNA in HCT116 cells.
, 2013 (A) RT-qPCR analysis to show the B7-H1 mRNA level. Parental or HCT116 cells transfected with scrambled siRNA or siRNA targeting B7-H1 for 48 h were harvested and RT-qPCR was performed; (B) Western blot analysis to detect the B7-H1 protein level. Parental
Ming Wei (466751) +7 more
core +1 more source
Evaluation of Mutation Risk Using Patient‐Derived Organoids in Patients With Lynch Syndrome
International Journal of Cancer, EarlyView.ABSTRACT Lynch syndrome (LS) is a hereditary cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes, most notably associated with colorectal cancer. Although LS patients face high risk of CRC, risk can vary even among those with the same pathogenic MMR germline mutations. We suggest a functional assay platform for
Youmi Shin +10 more
wiley +1 more source