Results 71 to 80 of about 4,460,555 (293)

Functional analyses of ARHGAP11A-knockdown HCT116 human colon cancer cells.

, 2013
(A) Establishment of ARHGAP11A-knockdown HCT116 cell lines (SH #1, #2). Decreased ARHGAP11A mRNA expression was confirmed by qPCR. (B) ARHGAP11A protein expression in control and sh-knockdown HCT116 cells was assessed by Western blotting.
Yuji Kamioka (503601), Masaru Ishii (257500), Shinji Matsumoto (503600), Michiyuki Matsuda (108803), Keizo Nishikawa (503607), Yoko Naito (201483), Ichiro Takemasa (1607), Masaki Mori (30875), Naohiro Nishida (503603), Junichi Nishimura (206586), Koshi Mimori (30872), Atsushi Naito (503605), Masataka Ikeda (428186), Taeko Ishii (503602), Hirofumi Yamamoto (1614), Yoshinori Kagawa (503599), Tsunekazu Mizushima (206584), Akira Kikuchi (202891), Naotsugu Haraguchi (503608), Junichi Kikuta (503606), Mitsugu Sekimoto (1613), Sakae Maeda (503604), Daisuke Okuzaki (482418), Yuichiro Doki (402704), Hideshi Ishii (30870)   +24 more
core   +1 more source

Slow Turning Lateral Vessel Bioreactor Improves Embryoid Body Formation and Cardiogenic Differentiation of Mouse Embryonic Stem Cells. [PDF]

, 2013
Embryonic stem cells (ESCs) have the ability to form aggregates, which are called embryoid bodies (EBs). EBs mimic early embryonic development and are commonly produced for cardiomyogenesis.
Tharasanit, T., Biology of Reproductive Cells, Pirity, M., Rungarunlert, Sasitorn, Klincumhom, Nuttha, Rungarunlert, S., Dinnyés, András, Tharasanit, Theerawat, Dep Gezondheidszorg Landbouwhuisdieren, Klincumhom, N., Techakumphu, M., Pirity, Melinda, Dinnyes, A.   +12 more
core   +2 more sources

Microprotein MP104 Promotes Malignant Progression of Colorectal Cancer Through Regulating Protein Translation

Advanced Science, EarlyView.
A previously unrecognized microprotein, MP104, encoded by ZEB1‐AS1, emerges as a critical driver of colorectal cancer progression. MP104 links ubiquitin‐mediated protein degradation with translational reprogramming via the UBE2O–AMPKα2–mTOR–EIF4B axis, revealing an unrecognized layer of oncogenic regulation.
Fang Chen, Miao Wang, Hongmei Yong, Jin Ding, Shiping Xu, Qirui Ge, Yan Wang, Lei Zhang, Qianqian Xiao, Benli Li, Li Lin, Sufang Chu, Qianqing Wang, Jin Bai, Pingfu Hou   +14 more
wiley   +1 more source

Sp5 negatively regulates the proliferation of HCT116 cells by upregulating the transcription of p27

Oncology Letters, 2018
The Wnt signaling pathway is aberrantly activated in the majority of human colorectal tumors. β-catenin, a key component of the Wnt signaling pathway, interacts with the T-cell factor/lymphoid enhancer-binding factor family of transcription factors and activates transcription of Wnt target genes.
Masaya, Miyamoto, Tomoatsu, Hayashi, Yoshihiro, Kawasaki, Tetsu, Akiyama   +3 more
openaire   +3 more sources

Expression of OR51B4 in HCT116 cells and colon cancer tissues.

, 2017
(A) Bar chart displays the FPKM values of the most highly expressed ORs in HCT116 cells. (B) Immunocytochemical staining of OR51B4 in HCT116 cells with a specific OR51B4-antibody. Left: HCT116 cells.
Stephan Hahn (534868), Janine Altmüller (120887), Juliane Ebbert (3821188), Hanns Hatt (120893), Günter Gisselmann (120878), Peter Jägers (3726508), Christian Becker (49615), Lea Weber (279365), Klaudia Al-Refae (3821185)   +8 more
core   +1 more source

Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States

Advanced Science, EarlyView.
Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton, Carrillo Paola Gonzalez, Luay Almassalha, Wing Shun Li, Ruyi Gong, Nicolas Acosta, I Chae Ye, Jane Frederick, Christopher Hogg, Saira John, J. A. Gareth Williams, Rikkert J. Nap, Igal Szleifer, Vadim Backman   +13 more
wiley   +1 more source

Cytotoxic Effects of Lactobacilli Isolated from Azerbaijan Traditional Cheeses on Colorectal Tumor Cells HCT 116 and Identification of Paramount Strains

Journal of Ardabil University of Medical Sciences, 2018
Background & objectives: Colorectal cancer is one of the most common cancers in the world. Much attention has been given to nutritional supplements that can alter intestinal flora as factors preventing colon cancer.
Mitra Rabiei, Gholamreza Zarrini, Majid Mahdavi   +2 more
doaj  

miR-340 reverses chemotherapy resistance in colon cancer via the PDCD4/WNT/β-catenin signalling pathway

Scientific Reports
The silencing of miR-340 has been implicated in the progression and migratory capacity of colorectal cancer (CRC); however, its role in modulating oxaliplatin-induced chemotherapy resistance in CRC remains largely unexplored.
Hanbing Xu, Xingwang Xie, Jiantao Han, Chengpeng Zhang   +3 more
doaj   +1 more source

VEGFR2 regulates endothelial differentiation of colon cancer cells

BMC Cancer, 2017
Background Recent studies suggested that cancer stem-like cells contribute to tumor vasculogenesis by differentiating into endothelial cells. However, such process is governed by still undefined mechanism. Methods At varying differentiation levels, three
Zhiyong Liu, Lisha Qi, Yixian Li, Xiulan Zhao, Baocun Sun   +4 more
doaj   +1 more source

Quantum Dots as a Good Carriers of Unsymmetrical Bisacridines for Modulating Cellular Uptake and the Biological Response in Lung and Colon Cancer Cells

Nanomaterials, 2021
Nanotechnology-based drug delivery provides a promising area for improving the efficacy of cancer treatments. Therefore, we investigate the potential of using quantum dots (QDs) as drug carriers for antitumor unsymmetrical bisacridine derivatives (UAs ...
Joanna Pilch, Patrycja Kowalik, Piotr Bujak, Anna M. Nowicka, Ewa Augustin   +4 more
doaj   +1 more source