Results 31 to 40 of about 425,993 (391)

Association of Hepatitis C viral load with liver functions and risk factors among HCV patients, Minia governorate, Egypt [PDF]

open access: yesNovel Research in Microbiology Journal, 2021
Hepatitis C virus (HCV) is one of the blood transmitted hepatitis viruses. HCV infections have been identified as major causes of chronic hepatic diseases, and hepatocellular carcinoma. The aims of the current study were to determine the HCV viral load
Hala, R. Ahmed   +5 more
doaj   +1 more source

Evidence for a Complex Mosaic Genome Pattern in a Full-length Hepatitis C Virus Sequence

open access: yesEvolutionary Bioinformatics, 2008
The genome of the hepatitis C virus (HCV) exhibits a high genetic variability. This remarkable heterogeneity is mainly attributed to the gradual accumulation of mutational changes, whereas the contribution of recombination events to the evolution of HCV ...
R.S. Ross   +5 more
doaj   +1 more source

Sustained virological response 12 versus sustained virological response 24 as evaluation endpoints in chronic hepatitis C virus Egyptian patients treated with sofosbuvir-based regimens

open access: yesThe Egyptian Journal of Internal Medicine, 2019
Background The recommended reliance on 12 weeks posttreatment sustained virological response (SVR12) instead of SVR24 was validated for treatment evaluation. Aim Judging claimed concordance between SVR12 and SVR24.
Maha M Elsabaawy   +9 more
doaj   +1 more source

The correlation of HCV RNA and HCV core antigen in different genotypes of HCV [PDF]

open access: yesJournal of Clinical Laboratory Analysis, 2018
BackgroundTo analyze the correlation of HCV RNA and HCV core antigen (HCV cAg) in different genotypes of HCV.MethodsOne hundred and six patients who were diagnosed with HCV infection by HCV RNA test were included in the study. HCV genotypes were detected by PCR fluorescent probe.
Yu Xiang   +3 more
openaire   +3 more sources

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

open access: yesHepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro   +17 more
wiley   +1 more source

Synopsis: Special Issue on “Disruption of signaling homeostasis induced crosstalk in the carcinogenesis paradigm Epistemology of the origin of cancer”

open access: yes4 open, 2019
It is increasingly evident that carcinogenesis, in the vast majority of cancers, cannot be explained simply through an accumulation of somatic mutations, or epigenetics, the stem cell theory, or the Warburg effect.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

Preferential association of hepatitis C virus with CD19+ B cells is mediated by complement system [PDF]

open access: yes, 2016
Extrahepatic disease manifestations are common in chronic hepatitis C virus (HCV) infection. The mechanism of HCV-related lymphoproliferative disorders is not fully understood.
Alter, Harvey J.   +7 more
core   +1 more source

Structure-activity relationships of fluorene compounds inhibiting HCV variants [PDF]

open access: yes, 2020
Approximately 71 million people suffer from hepatitis C virus (HCV) infection worldwide. Persistent HCV infection causes liver diseases such as chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma, resulting in approximately 400,000 deaths ...
Gadhe, Changdev G.   +10 more
core   +1 more source

Feasibility of anti-HCV reflex HCV Ag screening strategy in an HCV endemic community

open access: yesJournal of the Formosan Medical Association, 2021
The HCV core antigen (HCV Ag) assay displays high sensitivity and strong correlation with HCV RNA. However, the feasibility of anti-HCV reflex HCV Ag screening in a community-wide setting is rarely discussed.We performed a two-phase community-based hepatitis C screen in an HCV-prone area of central Taiwan.
Wei-Ming Chen   +6 more
openaire   +5 more sources

Attacking the public health crisis of hepatocellular carcinoma at its roots

open access: yesHepatology, EarlyView., 2022
Abstract As the third most common cause of cancer‐related death worldwide with significant mortality rates in the United States, hepatocellular carcinoma has strong association with cirrhosis and chronic hepatitis B virus (HBV) with a growing at‐risk population from the rise in chronic liver disease from alcohol use and nonalcoholic fatty liver disease.
Hannah M. Lee   +3 more
wiley   +1 more source

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