Results 51 to 60 of about 6,294 (108)
Acta Pharmaceutica, 2019 The aim of this work was to evaluate gellan gum as binder in pellet formulations, with theophylline as the model drug, in comparison with polyvinylpyrrolidone (PVP). A full 32 factorial design was realized, with binder and diluent factors at three levels
Barbosa Eduardo José +1 more
doaj +1 more source
Actualities in the phytochemical research on selected terpenes
Acta Pharmaceutica, 2019 A short review of our recent research on the essential oil phytochemical composition of Petasites albus (L.) Gaertn. and Petasites hybridus (L.) G. Gaertn., B. Mey. & Scherb.
Jerković Igor +2 more
doaj +1 more source
Screening of flavonoid aglycons’ metabolism mediated by the human liver cytochromes P450
Acta Pharmaceutica, 2019 Biological effects of flavonoids have been extensively studied in the last 80 years. As flavonoids represent a rather large group of compounds, data on metabolic biotransformations of these compounds is relatively limited to those well studied.
Benković Goran +3 more
doaj +1 more source
Low Fidelity Mutants in the O-Helix of Thermus aquaticus DNA Polymerase I*
Journal of Biological Chemistry, 1997 We screened 67 mutants in the O-helix of Thermus aquaticus (Taq) DNA polymerase I (pol I) for altered fidelity of DNA synthesis. These mutants were obtained (Suzuki, M., Baskin, D., Hood, L., and Loeb, L. A. (1996) Proc. Natl. Acad. Sci. U. S. A.
Motoshi Suzuki +3 more
semanticscholar +1 more source
Journal of Biological Chemistry, 1987 Recent results using proteases suggest that dexamethasone 21-mesylate (Dex-Mes) labeling of the rat hepatoma tissue culture (HTC) cell glucocorticoid receptor occurs at one or a few closely grouped cysteine residues (Simons, S.S., Jr. (1987) J.
S. Simons +3 more
semanticscholar +1 more source
Acta Pharmaceutica, 2017 L-carnitine-L-tartrate, a non-essential amino acid, is hygroscopic. This causes a problem in tablet production due to pronounced adhesion of tablets to punches. A 33 full factorial design was adopted to suggest a tablet formulation. Three adsorbents were
Badawi Aliaa A. +3 more
doaj +1 more source
Acta Pharmaceutica, 2014 A novel series of thiophenes having biologically active sulfonamide 2-11, 3-methylisoxazole 12, 4-methoxybenzo[d] thiazole 13, quinoline 14, 15, benzoylphenylamino 16, and anthracene-9,10-dione 17 moieties were prepared.
Ghorab Mostafa M. +2 more
doaj +1 more source
Effective anti-adhesives of uropathogenic Escherichia coli
Acta Pharmaceutica, 2018 Urinary tract infections (UTIs) caused by uropathogenic Escherichia coli (UPEC) are among the most common infectious diseases in humans. Due to their frequent occurrence in the community and nosocomial settings, as well as the development of resistance ...
Ribić Rosana +3 more
doaj +1 more source
Acta Pharmaceutica, 2018 The study describes the development and preliminary validation of a simple reverse-phase chromatographic method for determination of a novel drug candidate, 5-[(4-chlorophenoxy) methyl]-1,3,4-oxadiazole-2-thiol (OXCPM), in bulk and stressed solution, in ...
Shehzadi Naureen +8 more
doaj +1 more source