Results 201 to 210 of about 2,934,766 (329)

HDAC inhibitors restore osteoimmune balance and bone regeneration via selective MAPK modulation in inflammatory bone disease. [PDF]

Stem Cell Res Ther
Kim H, Kang L, Park SY.
europepmc   +1 more source

HDAC inhibitors enhance the anti-tumor effect of immunotherapies in hepatocellular carcinoma. [PDF]

Front Immunol, 2023
Shen C, Li M, Duan Y, Jiang X, Hou X, Xue F, Zhang Y, Luo Y.   +7 more
europepmc   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Advancements in Hydrazide-Based HDAC Inhibitors: A Review of Recent Developments and Therapeutic Potential. [PDF]

J Med Chem
Raucci A, Zwergel C, Valente S, Mai A.
europepmc   +1 more source

Epigenetic modifications regulate peg elongation and underground fruiting in peanut in response to environmental cues

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Epigenetic regulation plays a central role in coordinating peanut (Arachis hypogaea L.) fruit pegging, a unique developmental process in which fertilized ovaries transition from aerial growth to subterranean pod formation. This review synthesizes current evidence demonstrating that dynamic interactions among DNA methylation, histone ...
Yohannes Gelaye, Huaiyong Luo
wiley   +1 more source

Advances of HDAC inhibitors in tumor therapy: potential applications through immune modulation. [PDF]

Front Oncol
Tian J, Han M, Song F, Liu Y, Shen Y, Zhong J.   +5 more
europepmc   +1 more source

Combining EZH2 and HDAC inhibitors to target castration-resistant prostate cancers. [PDF]

PLoS Biol, 2023
Coulter JB, Easwaran H.
europepmc   +1 more source

The Prebiotic and Techno‐Functional Potential of Microbial Exopolysaccharides for Human Health and Food Systems

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 2, March 2026.
ABSTRACT Microbial exopolysaccharides (EPS) represent a diverse class of biopolymers holding considerable promise as functional food ingredients. This review analyzes the dual function of microbial EPS as a candidate for prebiotic agents and techno‐functional additives.
Md. Abdur Razzak, Hye Kim, Md. Ariful Haque, Min Ji Jang, Sehyeon Song, Anishka Talari, Lakshmi Devi Chittepu, Seockmo Ku   +7 more
wiley   +1 more source

Enhancing venetoclax efficacy in leukemia through association with HDAC inhibitors. [PDF]

Cell Death Discov
Carlos JAEG, Tavares MT, Lima K, de Almeida LC, de Barros Waitman K, Costa-Lotufo LV, Parise-Filho R, Machado-Neto JA.   +7 more
europepmc   +1 more source

Design, synthesis and biological evaluation of novel histone deacetylase (HDAC) inhibitors derived from β-elemene scaffold. [PDF]

J Enzyme Inhib Med Chem, 2023
Gao Y, Duan J, Dang X, Yuan Y, Wang Y, He X, Bai R, Ye XY, Xie T.   +8 more
europepmc   +1 more source