Results 211 to 220 of about 77,584 (306)

HDAC inhibitors as radiosensitizers

HDAC inhibitors as radiosensitizers
Radiation therapy is one of the main anticancer therapies. However, there are considerable numbers of radioresistant carcinoma cells and severe adverse effects occasionally occur after radiation therapy. Therefore, there have been many attempts to identify radiosensitizers.
openaire  

Postbiotic Supernatants From Psychobiotic Strains Modulate Antioxidant and Serotonergic Responses

eFood, Volume 7, Issue 3, June 2026.
Cell‐free postbiotic supernatants obtained from psychobiotic strains exhibit strain‐dependent antioxidant and serotonergic effects. SCFA‐rich metabolites enhance antioxidant protection and modulate serotonin release in enterochromaffin cells, supporting their potential as functional ingredients for gut and brain health.
Cocean Ana‐Maria, Zorita Diaconeasa, Calina Ciont, Razvan Odocheanu, Alexandra Machitescu, Floricuta Ranga, Dan Cristian Vodnar   +6 more
wiley   +1 more source

Normalization of hepatic homeostasis in the Npc1nmf164 mouse model of Niemann-Pick type C disease treated with the histone deacetylase inhibitor vorinostat [PDF]

, 2017
al, et, Ory, Daniel S.
core   +1 more source

Peripheral T‐Cell Lymphomas in Southern Taiwan: Epidemiology, Treatment Patterns, and Long‐Term Outcomes

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Peripheral T‐cell lymphomas (PTCLs) are heterogeneous neoplasms with poor prognosis and marked geographic variation. Data from Taiwan remain limited. We conducted a 15‐year retrospective cohort study of 249 patients diagnosed with PTCL at two major centers in southern Taiwan between 2010 and 2024 to characterize regional epidemiology, real ...
Bo‐Yu Huang, Li‐Chang Chang, Sheng‐Yen Hsiao, Ya‐Ping Chen, Sin‐Syue Li, Pei‐An Fu, Chen Chang, Kung‐Chao Chang, Tsai‐Yun Chen, Ya‐Ting Hsu   +9 more
wiley   +1 more source

HDAC inhibitors modulate Hippo pathway signaling in hormone positive breast cancer. [PDF]

Clin Epigenetics
Lin TI, Tseng YR, Dong MJ, Lin CY, Chung WT, Liu CY, Tsai YF, Huang CC, Tseng LM, Chao TC, Lai JI.   +10 more
europepmc   +1 more source

Metabolic Control of Epigenetics and Its Role in CD8+ T Cell Differentiation and Function [PDF]

, 2019
Glauben, Rainer, Siegmund, Britta, Weidinger, Carl, Yerinde, Cansu   +3 more
core   +1 more source

Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang, Qitai Chen, YuJie Yu, Yi Zang, Rujia Zheng, Zhe Zhang, Shuaijun Lu, Li Zhou   +7 more
wiley   +1 more source

Synergistic Integration of HDAC Inhibitors and Individualized Neoantigen Therapy (INT): A Next-Generation Combinatorial Approach for Cancer Immunotherapy. [PDF]

Vaccines (Basel)
Han R, Zhou H, Peng B, Yu S, Zhu J, Chen J.   +5 more
europepmc   +1 more source

HDAC Inhibitor CHR-2845 [PDF]

, 2020
openaire   +1 more source

Colorectal Precancerous Lesions: Molecular Mechanisms, Research Tools, and Natural Product‐Based Clinical Translation

MedComm – Oncology, Volume 5, Issue 2, June 2026.
This article systematically elucidates the molecular mechanisms of colorectal precancerous lesions, introduces cutting‐edge research tools like multi‐omics and organoids, and highlights the potential and prospects of natural products such as berberine, resveratrol, and curcumin in preventing and intervening in colorectal carcinogenesis by modulating ...
Shunji Liu, Chujuan Cui, Lingdong Kong, Qiang Xu, Haibo Cheng, Lisha Zhou, Yang Sun   +6 more
wiley   +1 more source