Results 101 to 110 of about 682,721 (387)

Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport

Nature Communications, 2017
Brown and beige adipocytes combust nutrients for thermogenesis and through their metabolic activity decrease pro-atherogenic remnant lipoproteins in hyperlipidemic mice. However, whether the activation of thermogenic adipocytes affects the metabolism and
A. Bartelt, A. Bartelt, C. John, Nicola Schaltenberg, J. Berbée, A. Worthmann, M. Cherradi, C. Schlein, Julia Piepenburg, M. Boon, F. Rinninger, M. Heine, K. Toedter, A. Niemeier, S. Nilsson, S. Nilsson, Markus Fischer, S. Wijers, W. Lichtenbelt, L. Scheja, P. Rensen, J. Heeren   +21 more
semanticscholar   +1 more source

HDL Metabolism and Atherosclerosis

Journal of Cardiovascular Pharmacology, 1990
Epidemiologic studies of recent years have demonstrated an association between low plasma high-density lipoprotein (HDL) cholesterol levels and the development of atherosclerosis. The PROCAM (Prospective Cardiovascular Münster) study has identified HDL cholesterol as the single parameter predictor with the highest potency.
Harald Funke, Gerd Assmann
openaire   +4 more sources

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

Plasma proteome correlates of lipid and lipoprotein: biomarkers of metabolic diversity and inflammation in children of rural Nepal. [PDF]

, 2019
Proteins involved in lipoprotein metabolism can modulate cardiovascular health. While often measured to assess adult metabolic diseases, little is known about the proteomes of lipoproteins and their relation to metabolic dysregulation and underlying ...
Christian, Parul, Cole, Robert N, Eroglu, Abdulkerim, Groopman, John, Lee, Sun Eun, Schulze, Kerry, Stewart, Christine P, West, Keith P, Wu, Lee S-F, Yager, James D   +9 more
core  

Lactate‐Activated GPR132‐Src Signal Induces Macrophage Senescence and Aggravates Atherosclerosis Under Diabetes

Advanced Science, EarlyView.
Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge, Shuying Wang, Zhaokai Li, Jing Yu, Binbin Liu, Ruiying Wang, Shichen Bu, Nawsher wan, Yan Wang, Cuilian Dai, Yijun Lin   +10 more
wiley   +1 more source

Approximately self-consistent resummations for the thermodynamics of the quark-gluon plasma. I. Entropy and density [PDF]

, 2000
We propose a gauge-invariant and manifestly UV finite resummation of the physics of hard thermal/dense loops (HTL/HDL) in the thermodynamics of the quark-gluon plasma. The starting point is a simple, effectively one-loop expression for the entropy or the
A. Peshier, A. Peshier, A. Rebhan, A.K. Rebhan, B. Vanderheyden, B.A. Freedman, B.A. Freedman, B.A. Freedman, C. De Dominicis, C. De Dominicis, C. Zhai, E. Braaten, E. Braaten, E. Iancu, E. Riedel, F. Flechsig, F. Karsch, F. Karsch, G. Baym, G. Boyd, G.M. Carneiro, H. Schulz, H.A. Weldon, H.A. Weldon, H.A. Weldon, I.T. Drummond, J. Frenkel, J. Frenkel, J. Frenkel, J.-P. Blaizot, J.-P. Blaizot, J.-P. Blaizot, J.-P. Blaizot, J.-P. Blaizot, J.-P. Blaizot, J.-P. Blaizot, J.-P. Blaizot, J.I. Kapusta, J.M. Luttinger, J.O. Andersen, J.O. Andersen, J.O. Andersen, K. James, K. Kajantie, K. Kajantie, L. Dolan, M. Laine, M. Le Bellac, M. Okamoto, O. Kaczmarek, O.K. Kalashnikov, P. Arnold, P. Arnold, P. Arnold, P. Lévai, R. Baier, R. Kobes, R.D. Pisarski, R.D. Pisarski, S. Chiku, T. Toimela, U. Heinz, U. Kraemmer, V. Baluni, V.V. Klimov, W. Kummer   +65 more
core   +2 more sources

Association of polymorphism apolipoprotein A1 with the lipid profile serum

Атеросклероз, 2010
Objective: to investigate apolipoprotein AI gene polymorphism and its associations with lipid profile in Caucasian population of West Siberia. The study included 100 persons with total cho lesterol >300 mg/dl, 100 – with total cholesterol < 200 mg/dl ...
E. V. Schakhtschneider, I. V. Kulikov, M. V. Ivanova, M. I. Voevoda   +3 more
doaj  

Peptide-Based HDL as an Effective Delivery System for Lipophilic Drugs to Restrain Atherosclerosis Development

International Journal of Nanomedicine, 2022
Junwei Gao,1 Ziyun Li,1 Jing Li,2 Ping Song,3 Jinsheng Yang,1 Wei Xiao,4 Ning Li,1 Ruodan Xu1 1Department of Biomedical Engineering and Technology, Institute of Basic Theory for Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing, People’
Gao J, Li Z, Li J, Song P, Yang J, Xiao W, Li N, Xu R   +7 more
doaj  

Relation of Paraoxonase1, Arylesterase and Lipid Profile in Ischemic Stroke Patients [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background: Paraoxonase 1 (PON1) is an enzyme associated with High density lipoprotein (HDL) in blood and it is considered to have antioxidant and antiatherogenic properties.
Seema Sanjay Chawhan, Mukund R Mogarekar, Reena V Wagh, Rajkumar R Das, Sanjay S Pramanik, Sanjay M Sonune, Sanjay M Chawhan   +6 more
doaj   +1 more source

CD74 Blockade Disrupts Endothelial Migrasome Signaling to Prevent Inflammatory Macrophage Differentiation and Inhibit Atherosclerotic Progression

Advanced Science, EarlyView.
Migrasomes play a crucial role in endothelial‐immune interactions in atherosclerosis. This study identifies migrasomes as amplifiers in the inflammatory cascade, driving immune‐metabolic reprogramming via “migrasome‐APP‐CD74” signaling. Blocking CD74 disrupts migrasome‐mediated signaling, attenuating atherosclerosis progression.
Kangnan Zhang, Jiong Chen, Zhenhua Zhu, Hong Hu, Qinghui Zhang, Rongrong Jia, Na Wang, Shihao Xiang, Yong Zhou, Yuehong Wang, Ling Xu   +10 more
wiley   +1 more source