Results 101 to 110 of about 428,492 (343)
Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9
We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen +16 more
wiley +1 more source
The aim of this paper was to examine whether moderate dyslipoproteinemia can cause an increase of hsCRP and LPO levels in Tx patients who had received immunosuppressive therapy and were without acute inflammatory diseases. Herein, the lipid levels, hsCRP,
Kimak Elzbieta +2 more
doaj +1 more source
Niaspan®: creating a new concept for raising HDL-cholesterol [PDF]
Mark E. McGovern
openalex +1 more source
An 18‐month HFD successfully established a translational Macaca fascicularis model replicating key metabolic disorders (MASH, diabetes, cardiac hypertrophy). MASH was determined by liver biopsy histology, the presence steatosis, inflammatory infiltration, hepatocytic ballooning, and fibrosis were considered as MASH; diabetes was diagnosed according to ...
Hongyi Chen +12 more
wiley +1 more source
Objective Identifying modifiable factors influencing amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) risk is important for prevention. Blood biomarkers, particularly cholesterol, have been associated with neurodegenerative risk, but findings in ALS are inconsistent, and data on FTD are limited.
Christos V. Chalitsios +5 more
wiley +1 more source
Stroke merupakan penyebab kematian ketiga di dunia dan merupakan penyebab kematian utama dengan peningkatan prevalensi yang signifikan setiap tahunnya di Indonesia.
Amelia Intan Saputri1, Meutia Maulina
doaj +1 more source
The HDL Proteome Watch: Compilation of studies leads to new insights on HDL function.
W. S. Davidson +3 more
semanticscholar +1 more source
Objectives To explore the association between the triglyceride to HDL-C ratio (TG/HDL-C) and insulin resistance in Chinese patients with newly diagnosed type 2 diabetes mellitus. Methods Patients with newly diagnosed type 2 diabetes mellitus (272 men and
Xingxing Ren +6 more
semanticscholar +1 more source
Ultra‐High Spin Hall Angle in Sputtered Sb2Te3 Topological Insulators via Pt Interfacial Engineering
Topological insulator Sb2Te3 demonstrates exceptional charge‐to‐spin conversion efficiency and thermal stability up to 400°C, showing great promise for spin–orbit torque memory applications. This study achieves high‐quality Sb2Te3 films on silicon substrates through optimized sputtering and introduces an ultrathin Pt interlayer to suppress interfacial ...
Qi Zhang +9 more
wiley +1 more source

