Results 61 to 70 of about 428,492 (343)

Prediction and risk factor analysis of obesity-related proteinuria among individuals with metabolic syndrome

open access: yesJournal of Diabetology, 2021
Objective: In the present modern era of time, poor and frantic lifestyle has led to an enumerate increase in the number of people with obesity and metabolic syndrome (MS).
Syed Vaziha Tahaseen   +3 more
doaj   +1 more source

High HDL-Cholesterol Paradox: SCARB1-LAG3-HDL Axis [PDF]

open access: yesCurrent Atherosclerosis Reports, 2021
Abstract Purpose of the Review To evaluate recent studies related to the paradox of high HDL-C with mortality and atherosclerotic cardiovascular disease (ASCVD) risk. Recent Findings Two observational studies (Cardiovascular Health in Ambulatory Care Research Team [CANHEART]
openaire   +2 more sources

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

open access: yesAdvanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou   +10 more
wiley   +1 more source

Association of FTO rs9939609 polymorphism with serum leptin, insulin, adiponectin, and lipid profile in overweight adults

open access: yesAdipocyte, 2020
FTO gene polymorphisms are associated with obesity and food intake. This study aimed to investigate the association of FTO rs9939609 polymorphism genotypes with serum glucose, lipid profile and serum hormones level. This cross-sectional study was carried
Mahsa Mehrdad   +5 more
doaj   +1 more source

Non-HDL Estimation Methods: Advancing Cardiovascular Disease Prediction [PDF]

open access: diamond, 2023
Akbar Md Akbar   +3 more
openalex   +1 more source

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

open access: yesAdvanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue   +13 more
wiley   +1 more source

Investigation of oxidative stress index and lipid profile in cattle with brucellosis [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2017
The aim of this study was to define the oxidative-antioxidative capacity and lipid profile in cattle with brucellosis. A total of 32 cattle of Simmental breed were used in the study, among those, 22 demonstrated microbiologically positive for brucellosis
Oğuz MERHAN   +5 more
doaj   +1 more source

The role and function of HDL in patients with diabetes mellitus and the related cardiovascular risk

open access: yesLipids in Health and Disease, 2017
Diabetes mellitus (DM) is a major public health problem which prevalence is constantly raising, particularly in low- and middle-income countries.
Marek Femlak   +3 more
semanticscholar   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

open access: yesAdvanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang   +18 more
wiley   +1 more source

تاثیر عصاره آبی-الکلی دانه خرنوب بر میزان گلوکز و لیپید های خون در موش صحرایی دیابتی نر [PDF]

open access: yesمجله دانشگاه علوم پزشکی سبزوار, 1970
زمینه و هدف: دیابت ملیتوس مهم ترین بیماری متابولیک انسان است که منجر به هیپرگلیسمی و هیپرلیپیدمی می شود. از آن جا که گیاهان دارویی منابع غنی از آنتی اکسیدان های طبیعی هستند و عوارض جانبی آن ها نیز کمتر است، تاثیر عصاره آبی-الکلی دانه خرنوب بر غلظت گلوکز ...
اسفندیار شریفی   +2 more
doaj  

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