Results 161 to 170 of about 15,184 (209)
Topological Stability and Transcritical Bifurcations in a Target-Cell-Limited Model of HBV-HDV Viral Interference. [PDF]
VirusesLachiany M.
europepmc +1 more source
HDV Pathogenesis: Unravelling Ariadne’s Thread [PDF]
Viruses, 2021 Hepatitis Delta virus (HDV) lies in between satellite viruses and viroids, as its unique molecular characteristics and life cycle cannot categorize it according to the standard taxonomy norms for viruses. Being a satellite virus of hepatitis B virus (HBV), HDV requires HBV envelope glycoproteins for its infection cycle and its transmission.
Sophie Clément, Francesco Negro
exaly +6 more sources
Combination of Novel Therapies for HDV [PDF]
Viruses, 2022 Treatment options for HDV have been limited to interferon alfa-based therapies with its poor efficacy to side effects ratio. Several novel therapies have now advanced into the clinic. As they each have a different mechanism of action, there is the potential for combination therapy.
Jeffrey S Glenn, Menashe Elazar
exaly +5 more sources
Quantitative HBsAg and HDV-RNA Levels in Chronic Delta Hepatitis
Liver International, 2010 Background: Hepatitis delta virus (HDV) causes severe liver disease. Aims: To investigate the quantitative HDV-RNA, HBsAg and hepatitis B virus (HBV)DNA levels in correlation to histological, biochemical and demographical parameters in patients with ...
George N Dalekos +2 more
exaly +3 more sources
Liver InternationalBackground and Aims: The prevalence of HDV infection in HBsAg carriers is about 9.9% in Italy. However, the real prevalence is underestimated because the anti-HDV test is not performed routinely in all HBsAg carriers. The aim of this study was to compare
Valentina Cossiga +2 more
exaly +2 more sources
Journal of Viral Hepatitis, 2014 SUMMARY. HDV infection still remains a serious public health problem in Amazonia. There are few data regarding the biomolecular aspects of HBV/HDV co-infection in this region. We studied 92 patients HBsAg+/anti-HDV IgG+ followed at the Hepatitis Referral
Mitermayer G Reis, A Kay, R Parana
exaly +2 more sources
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HDV evolution—will viral resistance be an issue in HDV infection?
Current Opinion in Virology, 2018Hepatitis D virus (HDV) is a hepatotropic subviral infectious agent, obligate satellite of the Hepatitis B virus (HBV) and is highly related to viroids. HDV affects around 5% of the 257 million chronic HBV-carriers worldwide, leading to the most severe form of chronic viral hepatitis.
David Tabernero +3 more
openaire +2 more sources
Correlation of IgM anti-hepatitis D virus (HDV) to HDV RNA in sera of chronic HDV
Hepatology, 1989One hundred forty-four serum samples from 52 patients with chronic hepatitis D virus infection were analyzed for hepatitis D virus RNA by dot-blot hybridization using hepatitis D virus cDNA probe labeled with 32p. The results were correlated with the presence of serum IgM anti-hepatitis D virus and hepatitis D antigen in liver
S, Govindarajan +3 more
openaire +2 more sources
Antiviral Research, 1994
Chronic hepatitis D is a usually severe and progressive liver disease due to infection with the hepatitis delta virus, a unique RNA virus requiring the hepatitis B virus helper function to exert its pathogenic potential. Alpha IFN is at present the treatment of choice for chronic viral hepatitis, but the results obtained in chronic hepatitis D are far ...
F, Rosina, R, Cozzolongo
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Chronic hepatitis D is a usually severe and progressive liver disease due to infection with the hepatitis delta virus, a unique RNA virus requiring the hepatitis B virus helper function to exert its pathogenic potential. Alpha IFN is at present the treatment of choice for chronic viral hepatitis, but the results obtained in chronic hepatitis D are far ...
F, Rosina, R, Cozzolongo
openaire +2 more sources
Combined HDV RNA and anti-HDV measurement for the management of HBV/HDV coinfection
HepatologyBackground and Aims: Virologic profiling is mandatory for the clinical management of hepatitis B surface antigen (HBsAg) carriers, positive for antibody against hepatitis delta virus (anti-HDV). We analyzed the correlations between serum HDV RNA, anti-HDV, HBV markers, and liver disease in a single-center cohort
Gabriele Ricco +13 more
openaire +2 more sources