Results 171 to 180 of about 15,184 (209)
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2006
Hepatitis delta virus (HDV) infection may occur as coinfection with hepatitis B virus (HBV) or as superinfection of a chronically HBV-infected patient. A strong antibody response is mounted, which persists for many years; however, it is not able to modulate the course of infection. In most cases the superinfection takes a chronic course.
M, Fiedler, M, Roggendorf
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Hepatitis delta virus (HDV) infection may occur as coinfection with hepatitis B virus (HBV) or as superinfection of a chronically HBV-infected patient. A strong antibody response is mounted, which persists for many years; however, it is not able to modulate the course of infection. In most cases the superinfection takes a chronic course.
M, Fiedler, M, Roggendorf
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The Use of Hepatocytes to Investigate HDV Infection: The HDV/HepaRG Model
Methods in Molecular Biology, 2010Worldwide, it is estimated that more than 350 million people are chronically infected with hepatitis B virus (HBV), approximately 15 million of whom are coinfected with hepatitis D virus (HDV), a satellite of HBV that uses the envelope proteins of the latter to assemble its infectious particles.
exaly +3 more sources
Bulevirtide for HBV and HDV infections
Drugs of Today, 2021Hepatitis B virus (HBV) and its satellite virus hepatitis D (HDV) are common worldwide hepatotrophic infections responsible for cirrhosis and hepatocellular carcinoma (HCC). The more common HBV infection has several therapeutic regimens currently available for suppression of viral replication.
D, Yardeni, C, Koh
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Digestive and Liver Disease, 2011
The hepatitis D virus (HDV) was discovered in Italy in the mid-1970s during a major outbreak of hepatitis D in the Mediterranean basin. The outbreak has been brought under control in Europe and throughout the industrialized world in the last twenty years; in parallel, the clinical pattern of HDV disease has consistently changed.
SMEDILE, Antonina, RIZZETTO, Mario
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The hepatitis D virus (HDV) was discovered in Italy in the mid-1970s during a major outbreak of hepatitis D in the Mediterranean basin. The outbreak has been brought under control in Europe and throughout the industrialized world in the last twenty years; in parallel, the clinical pattern of HDV disease has consistently changed.
SMEDILE, Antonina, RIZZETTO, Mario
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2006
The self-cleaving RNA sequences, or ribozymes, in the genomic and antigenomic strands of hepatitis delta virus (HDV) RNA fold into structures that are similar to each other but distinct from those of small ribozymes associated with the RNA replicons that infect plants.
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The self-cleaving RNA sequences, or ribozymes, in the genomic and antigenomic strands of hepatitis delta virus (HDV) RNA fold into structures that are similar to each other but distinct from those of small ribozymes associated with the RNA replicons that infect plants.
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Significance of IgM Anti-Hepatitis D Virus (HDV) in Chronic HDV Infection
Journal of Medical Virology, 1991AbstractIntrahepatic hepatitis D virus (HDV) antigen (HDAg) and serum HDV RNA are excellent markers of active HDV replication but the relation of IgM anti‐HDV to HDV replication and histological activity is less certain. To further elucidate the significance of serum IgM anti‐HDV, 90 paired sera and liver biopsies from 64 patients sero‐positive for ...
Graeme J Alexander +2 more
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Detection of HDV-RNA by PCR in serum of patients with chronic HDV infection
Journal of Hepatology, 1990In this paper, we studied the usefulness of polymerase chain reaction (PCR) in HDV-RNA detection. Using serial dilutions of serum samples of known concentrations of HDV-RNA, PCR was 10,000-times more sensitive than slot-blot hybridization. PCR was used for the detection of HDV-RNA in 33 serum samples negative to HDV-RNA by conventional slot-blot ...
A, Madejón +7 more
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Decrease in HDV endemicity in Italy
Journal of Hepatology, 1997To evaluate a possible variation in hepatitis D virus endemicity in Italy, the data from a multicentre study concerning HBsAg chronic carriers first observed in 31 liver units during 1992 were compared with the corresponding figures from a similar study performed in 1987.In both studies the methodology for the recruitment of cases was the same.
SAGNELLI E +6 more
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Strategies for the treatment of HBV/HDV
European Journal of Pharmacology, 2018An estimated 240 million people worldwide are chronically infected with the hepatitis B virus (HBV). Despite readily available vaccination, HBV infections remain highly prevalent. As established HBV infections constitute a strong risk factor for developing hepatocellular carcinoma their treatment is a major task for the health system.
Andreas, Krause +2 more
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The Woodchuck Model of HDV Infection
2006The Eastern woodchuck, Marmota monax, has been a useful model system for the study of the natural history of hepadnavirus infection and for the development and preclinical testing of antiviral therapies. The model has also been used for hepatitis delta virus (HDV).
J L, Casey, J L, Gerin
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