Results 11 to 20 of about 15,184 (209)

Circulation of HDV Genotypes in Brazil: Identification of a Putative Novel HDV-8 Subgenotype

Microbiology Spectrum, 2023
Hepatitis D virus (HDV) is classified into 8 genotypes (1 to 8) and several subgenotypes. In Brazil, HDV-3 and HDV-1 predominate; however, most of the diagnosis efforts and molecular studies are directed to the area of endemicity of the Amazon Basin ...
Francisco C. A. Mello, Tairine M. Barros, Giovana P. Angelice, Vanessa D. Costa, Vinicius M. Mello, Maria Inês M. C. Pardini, Elisabeth Lampe, Barbara V. Lago, Livia M. Villar   +8 more
doaj   +5 more sources

A Mathematical Model for Early HBV and -HDV Kinetics during Anti-HDV Treatment [PDF]

Mathematics, 2021
Hepatitis delta virus (HDV) is an infectious subviral agent that can only propagate in people infected with hepatitis B virus (HBV). HDV/HBV infection is considered to be the most severe form of chronic viral hepatitis.
Rami Zakh, Alexander Churkin, William Bietsch, Menachem Lachiany, Scott J. Cotler, Alexander Ploss, Harel Dahari, Danny Barash   +7 more
doaj   +4 more sources

HDV-Like Viruses [PDF]

Viruses, 2021
Hepatitis delta virus (HDV) is a defective human virus that lacks the ability to produce its own envelope proteins and is thus dependent on the presence of a helper virus, which provides its surface proteins to produce infectious particles. Hepatitis B virus (HBV) was so far thought to be the only helper virus described to be associated with HDV ...
Pérez-Vargas, Jimena, Pereira de Oliveira, Rémi, Jacquet, Stéphanie, Pontier, Dominique, François-Loïc, Cosset, Freitas, Natalia   +5 more
openaire   +6 more sources

AAV-HDV: An Attractive Platform for the In Vivo Study of HDV Biology and the Mechanism of Disease Pathogenesis [PDF]

Viruses, 2021
Hepatitis delta virus (HDV) infection causes the most severe form of viral hepatitis, but little is known about the molecular mechanisms involved. We have recently developed an HDV mouse model based on the delivery of HDV replication-competent genomes using adeno-associated vectors (AAV), which developed a liver pathology very similar to the human ...
Sheila Maestro, Nahia Gomez-Echarte, Gracian Camps, Carla Usai, Lester Suarez-Amaran, Africa Vales, Cristina Olague, Rafael Aldabe, Gloria González- Aseguinolaza   +8 more
openaire   +4 more sources

HDV infection in immigrant populations

Journal of Medical Virology, 2019
AbstractAimsLittle data have been published so far on the epidemiological aspects of hepatitis D virus (HDV) infection in immigrant populations and even poorer is the information on the virological, phylogenetic, and clinical aspects of this infection in these populations.
Coppola N., Alessio L., Onorato L., Sagnelli C., Sagnelli E., Pisaturo M.   +5 more
openaire   +3 more sources

Chronic Hepatitis B in the United States: Current Landscape, Unmet Needs and Future Directions. [PDF]

J Viral Hepat
ABSTRACT Chronic hepatitis B (CHB) infection represents a major public health challenge in the US, with substantial unmet needs related to timely diagnosis, treatment, monitoring and disease management. This narrative review explores the CHB landscape in the US, including gaps in patient care, the evolving therapeutic landscape, the clinical utility of
Cohen C, Esteban JP, Bobde S, Wong RJ.
europepmc   +2 more sources

A Novel Quantitative ELISA Demonstrates Lack of Correlation Between Serum HDV-RNA and Anti-HDV Antibody Levels in Chronic HDV Infection. [PDF]

J Viral Hepat
Infection with the hepatitis delta virus (HDV) causes the most aggressive type of viral hepatitis and frequently leads to liver cirrhosis and hepatocellular carcinoma.
Ariungerel N, Otgonbaatar K, Enkhjargal S, Erdembileg U, Byambabaatar S, Munkhjin B, Tsagaantsooj T, Enkhtaivan S, Ochirsum B, Bat-Ulzii P, Ochirbat E, Dashdorj N, Oidovsambuu O.   +12 more
europepmc   +2 more sources

Anti-Viral Treatment Eligibility and Treatment Uptake Among People With Chronic Hepatitis B in Australia: The REACH-B Study. [PDF]

J Viral Hepat
ABSTRACT Treatment indication for chronic hepatitis B (CHB) varies across clinical guidelines. This study evaluated treatment eligibility and uptake in a large Australian cohort of people with CHB. The REACH‐B study recruited people with CHB managed through a national network of healthcare services.
Hajarizadeh B, Nelson R, George J, Hanson J, Davies J, Martinello M, Brown T, Wong I, Hasan T, Mascarenhas L, O'Beirne J, Wade A, Capati M, Trotter G, Thomas S, Nash L, Cowie B, Allard N, Tu T, Tran L, Howard S, Monaghan R, Carter J, Tu E, Erratt A, Carson J, Dore GJ, Matthews GV, REACH‐B Study Group.   +28 more
europepmc   +2 more sources

HLA-A*11:01 Identifies Patients at Risk for Persistent Viraemia and Advanced Fibrosis in HDV Infection. [PDF]

Aliment Pharmacol Ther
The HLA‐A*11:01 allele is associated with persistent viraemia and advanced liver fibrosis in HDV infection. HLA‐A*11:01 carriers exhibit a reduced T‐cell repertoire, suggesting a narrower T‐cell response to the infection. ABSTRACT Background Hepatitis delta virus (HDV) infection causes the most severe form of viral hepatitis, with highly heterogeneous ...
Cortese MF, Palom A, Segura AR, Rudilla F, Rande EE, Lopez AP, Caellas DT, Romero JV, Ruiz-Cobo JC, Riveiro-Barciela M, Herrero MJ, Buti M.   +11 more
europepmc   +2 more sources

A Review of HDV Infection

Viruses, 2022
Hepatitis D is the most severe viral hepatitis. Hepatitis D virus (HDV) has a very small RNA genome with unique biological properties. It requires for infection the presence of hepatitis B virus (HBV) and is transmitted parenterally, mainly by superinfection of HBsAg carriers who then develop chronic hepatitis D.
Caviglia, Gian Paolo, Ciancio, Alessia, Rizzetto, Mario   +2 more
openaire   +3 more sources