Results 21 to 30 of about 24,460 (200)

Elevated serum levels of human epididymis protein 4 in adult patients with proliferative lupus nephritis

Frontiers in Immunology, 2023
BackgroundThis study aimed to access whether serum human epididymis protein 4 (HE4) level could identify lupus nephritis (LN) pathological classes in adults and children.MethodsThe serum HE4 levels of 190 healthy subjects and 182 patients with systemic ...
Liubing Li, Huiya Xu, Yuting Le, Runzhao Li, Qiong Shi, Hongji Zhu, Hongxu Xu, Laisheng Li, Min Liu, Fen Wang, Hui Zhang, Hui Zhang   +11 more
doaj   +1 more source

HE4 Transcription- and Splice Variants-Specific Expression in Endometrial Cancer and Correlation with Patient Survival [PDF]

, 2013
We investigated the HE4 variant-specific expression patterns in various normal tissues as well as in normal and malignant endometrial tissues. The relationships between mRNA variants and age, body weight, or survival are analyzed. ICAT-labeled normal and
Attewell, John, Broaddus, Russell, Chen, Haibin, Dowdy, Sean, Drapkin, Ronny, Fu, Alex, Jiang, Shi-Wen, Kalogera, Eleftheria, Li, Jinping, Podratz, Karl   +9 more
core   +2 more sources

Jost Function for Singular Potentials [PDF]

, 1999
An exact method for direct calculation of the Jost function and Jost solutions for a repulsive singular potential is presented. Within this method the Schrodinger equation is replaced by an equivalent system of linear first-order differential equations ...
C. V. Sukumar, E. A. Kolganova, H. W. Jang, J. N. L. Connor, J. N. L. Connor, L. D. Landau, R. A. Aziz, R. A. Aziz, R. G. Newton, S. A. Rakityansky, S. A. Rakityansky, S. A. Rakityansky, S. A. Sofianos, S. A. Sofianos, S. A. Sofianos, S. E. Massen, S. Nakaichi-Maeda, T. Cornelius, W. M. Frank, Y. H. Uang   +19 more
core   +2 more sources

HE4 as a Biomarker for Endometrial Cancer [PDF]

Cancers, 2021
There are currently no blood biomarkers in routine clinical use in endometrial carcinoma (EC). Human epididymis protein 4 (HE4) is a glycoprotein that is overexpressed in the serum of patients with EC, making it a good candidate for use as a diagnostic and/or prognostic biomarker.
Behrouzi, Roya, Barr, Chloe E., Crosbie, Emma J.   +2 more
openaire   +2 more sources

Human Epididymis Secretory Protein 4 (HE4) Compromises Cytotoxic Mononuclear Cells via Inducing Dual Specificity Phosphatase 6

Frontiers in Pharmacology, 2019
While selective overexpression of serum clinical biomarker Human epididymis secretory protein 4 (HE4) is indicative of ovarian cancer tumorigenesis, much is still known about the mechanistic role of the HE4 gene or gene product. Here, we examine the role
Nicole E. James, Nicole E. James, Matthew T. Oliver, Jennifer R. Ribeiro, Evelyn Cantillo, Rachael B. Rowswell-Turner, Kyu-Kwang Kim, Clinton O. Chichester, Paul A. DiSilvestro, Richard G. Moore, Rakesh K. Singh, Rakesh K. Singh, Naohiro Yano, Naohiro Yano, Ting C. Zhao   +14 more
doaj   +1 more source

Could HE4 level measurements during first-line chemotherapy predict response to treatment among ovarian cancer patients? [PDF]

PLoS ONE, 2018
This study assessed the prognostic value of HE4 marker measurements at various stages of first-line chemotherapy for ovarian cancer.The study consisted of 90 ovarian cancer patients, including 48 women undergoing primary surgical treatment and 42 ...
Anita Chudecka-Głaz, Aneta Cymbaluk-Płoska, Małgorzata Wężowska, Janusz Menkiszak   +3 more
doaj   +1 more source

Hypoxia-Induced Upregulation of HE4 Is Responsible for Resistance to Radiation Therapy of Gastric Cancer

Molecular Therapy: Oncolytics, 2019
Upregulation of human epididymis protein 4 (HE4) is often observed in different types of cancers, including gastric cancer (GC), but the association of elevated HE4 level with radiation resistance in GC remains unclear.
Chunwei Peng, Guangjie Liu, Kai Huang, Qiang Zheng, Yunsong Li, Changjun Yu   +5 more
doaj   +1 more source

Diagnostic Research of CT Combined with Serum CA125 and HE4 in Ovarian Epithelial Malignant Tumor

CT Lilun yu yingyong yanjiu, 2022
Objective: To explore the diagnostic value of CT combined with serum CA125 and HE4 in ovarian epithelial malignant tumor. Methods: 156 cases of epithelial ovarian tumors (benign 72 cases, malignant 84 cases) were studied. Detections of CT and serum tumor
Desheng WANG, Fanggong KAN, Zhoupeng MA
doaj   +1 more source

Elevation of serum human epididymis protein 4 (HE4) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) as predicting factors for the occurrence of acute kidney injury on chronic kidney disease: a single-center retrospective self-control study

Frontiers in Pharmacology, 2023
Objectives: To evaluate whether novel biomarkers of renal injury, serum HE4 and NT-proBNP could predict acute kidney injury (AKI) on chronic kidney disease (CKD) (A on C) and assess the specificity and efficiency of serum creatinine (SCr), HE4 and NT ...
Jinye Song, Ling Chen, Zheping Yuan, Xuezhong Gong   +3 more
doaj   +1 more source

Diagnostic and prognostic value of HE4 in female patients with primary peritoneal carcinoma

The International Journal of Biological Markers, 2018
Background: HE4 is a useful tumor marker for the diagnosis of ovarian, endometrial, and fallopian tube carcinoma. Aim: The aim of our study was to investigate the value of serum HE4 compared with CA125 in the diagnosis of primary peritoneal carcinoma and
Dong Mi, Yuexiang Zhang
doaj   +1 more source