Results 41 to 50 of about 24,460 (200)

Machine Learning‐Enhanced Analysis of Exosomal Surface Sialic Acid Using Surface‐Enhanced Raman Spectroscopy for Ovarian Cancer Diagnosis and Therapeutic Monitoring

Advanced Science, EarlyView.
Machine learning‐assisted surface‐enhanced Raman spectroscopy analysis of exosomal sialic acid for ovarian cancer diagnosis, as well as independent monitoring of exosomal sialic acid expression levels across different treatment periods, reveals a potential correlation with treatment response.
Lili Cong, Jiaqi Wang, Sijun Huang, Xiaxia Man, Yi Guo, Shuping Xu, Songling Zhang   +6 more
wiley   +1 more source

Overexpression of HE4/WFDC2 gene in mice leads to keratitis and corneal opacity

Open Life Sciences
HE4 is overexpressed in malignant lesions, and elevated serum HE4 levels have been applied as a biomarker for gynecologic cancers. While previous studies have demonstrated the HE4 activities in cancer biology, its role(s) in benign disease is unclear. In
Tuo Lingjin, Zhang Taojun, Xu Xiaolun, Lin Jian, Wang Fengchao, Xu Hao, Jiang Shi-Wen   +6 more
doaj   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

The diagnosis and pathological value of combined detection of HE4 and CA125 for patients with ovarian cancer

Open Medicine, 2016
To evaluate the value of individual and combined measurement of human epididymis protein 4 (HE4) and cancer antigen 125 (CA-125) in the diagnosis of ovarian cancer.
Zheng Li-e, Qu Jun-ying, He Fei
doaj   +1 more source

Biomarker‐Agnostic Detection of Ovarian Cancer from Blood Plasma Using a Machine Learning‐Driven Electronic Nose

Advanced Intelligent Systems, EarlyView.
This study introduces a biomarker‐agnostic diagnostic strategy for ovarian cancer, utilizing a machine learning‐enhanced electronic nose to analyze volatile organic compound signatures from blood plasma. By overcoming the dependence on specific biomarkers, this approach enables accurate detection, staging, and cancer type differentiation, offering a ...
Ivan Shtepliuk, Lingyin Meng, Christer Borgfeldt, Jens Eriksson, Donatella Puglisi   +4 more
wiley   +1 more source

Quantum plasticity and dislocation-induced supersolidity [PDF]

, 2008
We suggest that below a certain temperature T_k, the free energy for the creation of kinks-antikinks pairs in the dislocation network of solid He4 becomes negative.
Andreev, Balibar, Blackburn, Boninsegni, Boninsegni, Boninsegni, Boninsegni, Bouchaud, Ceperley, Ceperley, Ceperley, Chester, Clark, Clark, Day, de Gennes, Feynman, Fisher, Giulio Biroli, Hirth, Ho, Jean-Philippe Bouchaud, Josserand, Kim, Kim, Leggett, Mukharsky, Nussinov, Philips, Pollet, Pollock, Prokof'ev, Rittner, Rittner, Sasaki, Shevchenko, Toner, Tucker, Zinn-Justin   +38 more
core   +3 more sources

The cervico‐vaginal DNA methylation WID‐qEC test: An epigenetic marker associated with ovarian cancer in the absence of endometrial and cervical cancer

International Journal of Cancer, EarlyView.
What's New? The DNA methylation‐based WID‐qEC test has been validated for the accurate detection of endometrial and cervical cancers using cervico‐vaginal samples. However, a small proportion of women test positive despite the absence of these cancers. This study explored the associated biological and clinical characteristics to inform potential follow‐
Elisa Redl, Chiara Herzog, Charlotte Vavourakis, James Barrett, Allison Jones, Iona Evans, Daniel Reisel, Ranjit Manchanda, Line Bjørge, Michal Zikan, David Cibula, Twana Alkasalias, Angelique Flöter Rådestad, Kristina Gemzell‐Danielsson, Louis Dubeau, Nicola MacDonald, Davor Jurkovic, Nora Pashayan, Martin Widschwendter   +18 more
wiley   +1 more source

Enhanced Expression of Human Epididymis Protein 4 (HE4) Reflecting Pro-Inflammatory Status Is Regulated by CFTR in Cystic Fibrosis Bronchial Epithelial Cells

Frontiers in Pharmacology, 2021
Decreased human epididymis protein 4 (HE4) plasma levels were reported in cystic fibrosis (CF) patients under CFTR potentiator ivacaftor therapy, which inversely correlated with lung function improvement.
Zsolt Bene, Zsolt Bene, Zsolt Bene, Zsolt Fejes, Zsolt Fejes, Tibor Gabor Szanto, Ferenc Fenyvesi, Judit Váradi, Luka A. Clarke, Gyorgy Panyi, Milan Macek, Margarida D. Amaral, István Balogh, István Balogh, Béla Nagy, Béla Nagy   +15 more
doaj   +1 more source

iPTF13bvn: The First Evidence of a Binary Progenitor for a Type Ib Supernova [PDF]

, 2014
The recent detection in archival HST images of an object at the the location of supernova (SN) iPTF13bvn may represent the first direct evidence of the progenitor of a Type Ib SN.
Anupama, G. C., Benvenuto, Omar G., Bersten, Melina C., Folatelli, Gaston, Kuncarayakti, Hanindyo, Nomoto, Ken'ichi, Quimby, Robert, Sahu, Devendra K., Srivastav, Shubham   +8 more
core   +3 more sources

Exploring the impact of microbial dysbiosis on ovarian cancer and the therapeutic potential of probiotics

VIEW, EarlyView.
Ovarian cancer has been linked to the microbiome as a potential environmental contributor, but how this association relates to tumor progression remains unclear. By comparing tumor and nontumor tissues, we identified a severity‐associated microbial and metabolic signature and showed that probiotics can partially restore immune balance and slow tumor ...
Chanyuan Li, Nalan Tu, Xin Ning, Yunyan Cong, Fei Wu, Xiuli Zhang, Runrong Li, Yue Xu, Binqiao Wang, Liqin Jin, Yuanming Shen, Jihong Liu   +11 more
wiley   +1 more source