Results 21 to 30 of about 28,557 (262)

Urine CA125 and HE4 for the Detection of Ovarian Cancer in Symptomatic Women

Cancers, 2023
Simple Summary Early diagnosis of ovarian cancer is challenging due to vague symptoms and a lack of screening tools. We aimed to evaluate two simple, non-invasive urine biomarkers, CA125 and HE4, for the diagnosis of ovarian cancer in symptomatic women ...
Chloe E. Barr, K. Njoku, G. Owens, E. Crosbie   +3 more
semanticscholar   +1 more source

Establishment and validation of reference intervals for tumor markers (AFP, CEA, CA19‐9, CA15‐3, CA125, PSA, HE4, Cyfra 21‐1, and ProGRP) in primary care centers in Korea: A cross‐sectional retrospective study

Health Science Reports, 2023
The reference interval (RI) for a tumor marker may vary between populations, detection systems, and the methods used to obtain their values. The aims of this study were to establish age‐ and sex‐specific RIs for the following nine common tumor markers ...
E. Nah, Seon Cho, H. Park, Suyoung Kim, Eunjoo Kwon, Han-Ik Cho   +5 more
semanticscholar   +1 more source

The diagnostic accuracy of two human epididymis protein 4 (HE4) testing systems in combination with CA125 in the differential diagnosis of ovarian masses [PDF]

, 2011
Background: Cancer antigen 125 (CA125) is the best known single tumor marker for ovarian cancer (OC). We investigated whether the additional information of the human epididymis protein 4 (HE4) improves diagnostic accuracy.
Burges, Alexander, Fuerst, Sophie, Hertlein, Linda, Hofmann, Karin, Kirschenhofer, Angela, Krocker, Katja, Lenhard, Miriam, Mayr, Doris, Nagel, Dorothea, Stieber, Petra   +9 more
core   +1 more source

Evaluation of He4 Use in the Diagnosis of Ovarian Cancer: First and Second Recurrence, and an Analysis of HE4 Concentration during Second- and Third-Line Chemotherapy

Diagnostics, 2023
HE4 is a commonly used tumor marker for ovarian cancer (OC) diagnosis. In our study, we aimed to assess its use in the diagnosis of subsequent OC recurrences and to evaluate its changes during recurrence diagnosis and the subsequent lines of chemotherapy
A. Chudecka-Głaz, A. Strojna, Kaja Michalczyk, S. Wieder-Huszla, K. Safranow, Edyta Skwirczyńska, A. Jurczak   +6 more
semanticscholar   +1 more source

Biomarkers and algorithms for diagnosis of ovarian cancer: CA125, HE4, RMI and ROMA, a review

Journal of Ovarian Research, 2019
Ovarian cancer is the 5th leading cause of death for women with cancer worldwide. In more than 70% of cases, it is only diagnosed at an advanced stage. Our study aims to give an update on the biological markers for diagnosing ovarian cancer, specifically
V. Dochez, H. Caillon, E. Vaucel, J. Dimet, N. Winer, G. Ducarme   +5 more
semanticscholar   +1 more source

Combination of serum CST1 and HE4 for early diagnosis of endometrial cancer

PeerJ, 2023
Purpose Optimal serological biomarkers have been absent for the early diagnosis of endometrial cancer, to date. In this study, we aimed to define the diagnostic performances of individual and combined detection of serum cysteine protease inhibitor 1 ...
Wenhui Zhong, Yunliang Liu, Liangming Zhang, Wanzhen Zhuang, Jianlin Chen, Zhixin Huang, Yue Zheng, Yi Huang   +7 more
semanticscholar   +1 more source

Knockdown of HE4 suppresses aggressive cell growth and malignant progression of ovarian cancer by inhibiting the JAK/STAT3 pathway

Biology Open, 2019
Human epididymis protein 4 (HE4) is well known to be a predictor of ovarian cancer clinically. HE4 is reported to play crucial roles in ovarian cancer progression and metastasis.
Aihong Wang, Canhui Jin, Xiaoyu Tian, Ying Wang, Hongyu Li   +4 more
doaj   +1 more source

Diagnostic value of CA125, HE4, and systemic immune-inflammation index in the preoperative investigation of ovarian masses

Medicine, 2023
This study aimed to ascertain the diagnostic accuracy of CA125, HE4, systemic immune-inflammation index (SII), fibrinogen-to-albumin ratio (FAR), prognostic nutritional index (PNI), and their combination for ovarian cancer (OC) to discover an optimal ...
Liyun Song, Jie Qi, Jing Zhao, Suning Bai, Qi Wu, Ren Xu   +5 more
semanticscholar   +1 more source

Comparison Between HE4, CA-125, and Combination of Both HE4 and CA-125 as Tumor Markers for Epithelial Ovarian Carcinoma Patients

Indonesian Journal of Cancer, 2012
Tujuan: Mengetahui dan membandingkan sensitivitas, spesifisitas, Positive Predictive Value, dan Negative Predictive Value antara HE4, CA-125, serta kombinasi HE4 dan CA-125 sebagai tumor marker pada pasien kanker ovarium tipe epitel.
PUNGKY MULAWARDHANA, BRAHMANA ASKANDAR, SOEHATNO   +2 more
doaj   +1 more source

Role of Human Epididymis Protein 4 (HE4) in Determining Survival of Patients With Endometrial Cancer: A Meta-Analysis

Technology in Cancer Research & Treatment, 2020
Background: Human epididymis protein 4 (HE4) is a novel cancer biomarker. This study evaluates the prognostic role of HE4 in determining the survival of endometrial cancer patients. Methods: Literature search was conducted in electronic databases (Embase,
Ying He MD, Jing Wang MD, Chun-Xing Ma MD, Yan-Hua Kang MD   +3 more
doaj   +1 more source