This study revealed that oncogene Collaborator of ARF (CARF) is closely related to B‐cell lymphoma tumorigenesis, and shares a conserved mechanism regulating protein stability with Arabidopsis Kip‐Related Protein6 (KRP6) through casein kinase 1‐mediated phosphorylation. Reduced phosphorylation led to the enhanced protein stability of CARF, resulting in
Li Qu+7 more
wiley +1 more source
Image‐enhanced endoscopy for detection of second primary neoplasm in patients with esophageal and head and neck cancer: A systematic review and meta‐analysis [PDF]
Chen‐Shuan Chung+5 more
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The co‐delivery of mRNAs encoding a CD47 inhibitor and a cytokine cocktail (interleukins 12, 15, and 21) via lipid nanoparticles enables effective localized immunotherapy. This strategy not only suppresses tumor progression but also enhances type 1 conventional dendritic cell (cDC1) differentiation and activates CD8+ T cells, thereby inducing robust ...
Tao Jiang+14 more
wiley +1 more source
Coping strategies of nurses in the care of patients with head and neck neoplasms [PDF]
Naira Agostini Rodrigues dos Santos+2 more
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Recent Advances in mRNA Delivery Systems for Cancer Therapy
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang+9 more
wiley +1 more source
New apigel local use at treatment of oral mucous membrane radiation reactions in patients after head and neck malignant neoplasms radiation therapy = Локальное применение нового апигеля для лечения лучевых реакций слизистой оболочки полости рта у больных после лучевой терапии злокачественных новообразований в области головы и шеи [PDF]
Л. С. Кравченко+3 more
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This review compares clinical outcomes, translational progress, and global funding trends across cancer phototherapies—photodynamic, photothermal, and photoimmunotherapy—and conventional immunotherapy. It highlights differences in treatment efficacy, clinical trial status, financial investment, and regulatory challenges, providing a comprehensive ...
Deepak S. Chauhan+6 more
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Carcinosarcoma of Head and Neck; Clinicopathological Characteristics, Treatment and Outcomes of Unique Neoplasm [PDF]
Garima Singh, Deepti D. Sharma
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This study uses single‐nucleus RNA sequencing and spatial transcriptomics to investigate penile squamous cell carcinoma (PSCC). It reveals that PSCC tumor cells mimic normal penile epithelium differentiation, independent of HPV status. The Tum_1 subtype shows basal stem‐like characteristics and promotes invasiveness. HPV‐positive basal stem‐like tumors
Hongjian Song+37 more
wiley +1 more source