Results 81 to 90 of about 155,739 (370)

Incidental finding of lymphoma after septoplasty. [PDF]

, 2016
IntroductionSeptoplasty, or surgical correction of the deviated septum, is an elective, routinely performed rhinologic procedure to address nasal airway obstruction.
Bhuta, Sunita M, Kedeshian, Paul A, Kuan, Edward C, Palma Diaz, Miguel Fernando, Suh, Jeffrey D, Tajudeen, Bobby A   +5 more
core   +2 more sources

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Molecular Pathology of Skin Neoplasms of the Head and Neck

Archives of Pathology & Laboratory Medicine, 2014
Context.— Skin neoplasms include the most common malignancies affecting humans. Many show an ultraviolet (UV)–induced pathogenesis and often affect the head and neck region.Objective.— To review literature on cutaneous neoplasms that show a predilection for the head and neck region and that are associated with molecular alterations.Data Sources ...
Scott R. Granter, Stefan Kraft
openaire   +3 more sources

Second primary cancer risk - the impact of applying different definitions of multiple primaries: results from a retrospective population-based cancer registry study [PDF]

, 2014
Background: There is evidence that cancer survivors are at increased risk of second primary cancers. Changes in the prevalence of risk factors and diagnostic techniques may have affected more recent risks.<p></p> Methods: We examined the
A Chopra, A Mehnert, Aishah Coyte, C Dong, C Fabbri, C Thellenberg, CH Johnson, D Brewster, D Brewster, D Brewster, D Forman, D Groheux, D Howel, David S Morrison, DM Parkin, DM Parkin, DR Youlden, E Crocetti, E Kellen, EM Ibrahim, F Levi, GB Yang, I Soerjomataram, IARC/ENCR/IACR Working Group, International Agency for Research on Cancer, J Ferlay, J Jegu, J Maddams, JA Atienza, JW Hotchkiss, K Hemminki, K Hemminki, K Moser, L Liu, L Liu, L Mellemkjaer, LJ Rutten, MB Adamo, MH Schmid-Wendtner, Philip McLoone, RE Curtis, S Scholes, X Gao, Y Chen   +43 more
core   +3 more sources

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Getting personal: Head and neck cancer management in the era of genomic medicine [PDF]

, 2016
BackgroundGenetic testing is rapidly becoming an important tool in the management of patients with head and neck cancer. As we enter the era of genomics and personalized medicine, providers should be aware of testing options, counseling resources, and ...
Abecasis, ACMG Board of Directors, ACMG Board of Directors, Agrawal, American College of Medical Genetics Board of Directors, American Society of Clinical Oncology, Ang, Appelbaum, Beauchamp, Bombard, Bombard, Bonner, Brierley, Brose, Burke, Cancer Genome Atlas Research Network, Cassa, Castro, Chapman, Conley, Crites, Culos, Dickert, Domchek, Eiler, Elisei, Evans, Everett, Ferner, Forbes, Green, Hampel, Hindorff, Hudson, Jemal, Keedy, Klitzman, Kloos, Lacko, Lenders, Lindor, MacLeod, Maher, Nichols, Offit, Pentz, Quillin, Rangel, Reilly, Robson, Ross, Rubin, Schlumberger, Schmitz, Shuman, Slamon, Stadler, Stransky, Sulmasy, Syvänen, Tan, Thakker, Uhlmann, Vermorken, Weeks, Wells, Wolf, Zettler   +67 more
core   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Head and Neck Lymphomas in HIV Patients: a Clinical Perspective

International Archives of Otorhinolaryngology, 2017
Introduction Because of the many HIV-related malignancies, the diagnosis and treatment of lymphoma in patients infected with human immunodeficiency virus are challenging.
Natsuki Oishi, José Vicente Bagán, Karla Javier, Enrique Zapater   +3 more
doaj   +1 more source

Biphenotypic Sinonasal Sarcoma-Case Report and Review of Clinicopathological Features and Diagnostic Modalities. [PDF]

, 2019
Background Biphenotypic sinonasal sarcoma is a recently described malignancy showing dual differentiation with both myogenic and neural elements. Due to its histologic similarities to other sinonasal malignancies, it is a diagnostic challenge.
Chitguppi, Chandala, Collura, Kaitlin, Curtis, Mark, Koszewski, Ian, Nyquist, Gurston G., Rabinowitz, Mindy R., Rosen, Marc   +6 more
core   +2 more sources

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source