Results 61 to 70 of about 198,685 (310)
ASSESSMENT OF BLOOD SERUM PROTEOME IN PATIENTS WITH SQUAMOUS CELL HEAD AND NECK CARCINOMA
Сибирский онкологический журнал, 2016 We compared the serum proteome profiles of squamous cell head and neck carcinoma patients with metastases, without metastases and healthy volunteers using the combination of gradient gel-electrophoresis (1D-SDS PAGE) and mass-spectrometry.
G. V. Kakurina +4 more
doaj
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
The Journal of Pathology: Clinical Research, 2022 The differentiation between a pulmonary metastasis and a newly developed squamous cell carcinoma of the lung in patients with prior head and neck squamous cell carcinoma (HNSCC) is difficult due to a lack of biomarkers but is crucially important for the ...
Annika Richter +12 more
doaj +1 more source
Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics
Advanced Science, EarlyView.The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu +4 more
wiley +1 more source
Biomarkers in head and neck squamous cell carcinoma: unraveling the path to precision immunotherapy
Frontiers in OncologyRecent strides in understanding the molecular underpinnings of head and neck cancers have sparked considerable interest in identifying precise biomarkers that can enhance prognostication and enable personalized treatment strategies.
Kamal S. Saini +24 more
doaj +1 more source
Neoplasia: An International Journal for Oncology Research, 1999 Replication-competent virus vectors are attractive therapeutic agents for cancer. G207, a second-generation, multimutated herpes simplex virus type 1 (HSV-1), is one such vector that is safe in primates and efficacious against human tumors in athymic ...
Ali Chahlavi +3 more
doaj +1 more source
Cancer-Associated Fibroblasts Modulate Transcriptional Signatures Involved in Proliferation, Differentiation and Metastasis in Head and Neck Squamous Cell Carcinoma [PDF]
, 2021 Emilia Wiecheć +7 more
openalex +1 more source
Head and Neck, 2019 Programmed cell death‐1 (PD‐1) pathway inhibition in head and neck squamous cell carcinoma (HNSCC) has demonstrated inconsistent efficacy regarding human papillomavirus (HPV) status and PD‐L1 expression.
J. Patel +4 more
semanticscholar +1 more source
Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion
Advanced Science, EarlyView.FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao +8 more
wiley +1 more source
Identification of Immune Subtypes for Predicting the Prognosis of Patients in Head and Neck Squamous Cell Carcinoma [PDF]
, 2021 Jing Sun +6 more
openalex +1 more source