Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Feeling safe, feeling connected: aesthetic and polyvagal approaches to dementia care. [PDF]
Fox S +5 more
europepmc +1 more source
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Comparing Thriving at Work Among Trans-Tasman Early-Career Nurses: A Multinational Cross-Sectional Study. [PDF]
Moloney W +3 more
europepmc +1 more source
Informing the development of an emotional health and wellbeing framework for children and young people in Northern Ireland. May 2019 [PDF]
Dorris, Claire +2 more
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We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
Support for the wellbeing of frontline healthcare workers should be incorporated in health emergency preparedness planning. [PDF]
McNeil K +6 more
europepmc +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Unexplored dimension of shift work: the effects of late-early shifts on nurses and their wellbeing - a qualitative study. [PDF]
Karki U, Dafny HA.
europepmc +1 more source
Strategic principles and capacity building for a whole-of-systems approaches to physical activity [PDF]
Allender, Steve +4 more
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