Results 101 to 110 of about 3,362,703 (342)

Healthcare

, 2020
Healthcare is the most complex area addressed in this book. It is a data-rich environment and data dependent. Often healthcare delivery is time critical; it experiences high demand and under surge conditions is reliant on individual or groups of human healthcare workers.
Faulkner, Alastair, Nicholson, Mark
openaire   +2 more sources

Knowledge of mpox and its determinants among the healthcare personnel in Arabic regions: A multi-country cross-sectional study

, 2023
Sarya Swed, Haidara Bohsas, Muhammad Mainuddin Patwary, Ismail Ibrahim, Amine Rakab, Abdulqadir J. Nashwan, Wael Hafez, Noheir Ashraf Ibrahem Fathy Hassan, Sheikh Shoib, Mohamed Elsayed, Bisher Sawaf, Mhd Kutaiba Albuni, Elias Battikh, Gihan mustafa kamal Mohamed, Adel Albozom, Ebrahim Shaddad, Sherihan Fathey, Mila Nu Nu Htay, Sanjit Sah, Iván Chérrez-Ojeda, Aroop Mohanty, Bijaya Kumar Padhi, Alfonso J. Rodríguez‐Morales, Aravind P. Gandhi, Ranjit Sah   +24 more
openalex   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Being pragmatic about healthcare complexity: our experiences applying complexity theory and pragmatism to health services research [PDF]

, 2018
Katrina M. Long, Fiona McDermott, Graham Meadows   +2 more
openalex   +1 more source

Prevalence and Associated Factors of Low Back Pain Among Healthcare Professionals at University of Gondar Comprehensive and Specialized Hospital, Northwest Ethiopia: Cross-Sectional Study

, 2022
Nini Asfaw Negash, Azmeraw Tadele, Abebaw Jember Ferede   +2 more
openalex   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Prevalence of frailty and contributory factors in three Chinese populations with different socioeconomic and healthcare characteristics [PDF]

, 2015
Jean Woo, Zheng Zheng, Jason Leung, Piu Chan   +3 more
openalex   +1 more source

Applying Lean Healthcare to Improve the Discharge Process in a Mexican Academic Medical Center [PDF]

, 2021
Rodrigo E. Peimbert-García, Luis Meave Gutiérrez-Mendoza, Heriberto García-Reyes   +2 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source