Results 101 to 110 of about 4,326,321 (342)

Balancing Healthcare and Economy Amidst the COVID-19 Pandemic: An Indian Experience

open access: yesRisk Management and Healthcare Policy, 2021
Ruby Dhar,1,* Babban Jee,2,* Subhradip Karmakar1 1Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India; 2Department of Health Research, Ministry of Health and Family Welfare, Government of India, New Delhi, India*These ...
Dhar R, Jee B, Karmakar S
doaj  

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

open access: yesFEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo   +4 more
wiley   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

In Pursuit of Affordable Health Care: On the Ground Lessons From Families in Massachusetts [PDF]

open access: yes, 2009
Based on focus group discussions, compares the coverage and healthcare costs of families with employer-sponsored insurance and those without after the state's 2006 healthcare reform.
Barbara Lyons   +2 more
core  

Analysis of the regulation of undecaprenyl diphosphate dephosphorylation in Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
BacA, PgpB, and YbjG phosphatases are involved in undecaprenyl phosphate (C55P) synthesis in Escherichia coli. We analyzed the lipid contents and the gene expression in the gene‐disruption strains. Undecaprenyl diphosphate (C55PP) level increased in the bacA, ybjG double‐disruption strain, but C55P levels were similar in all strains.
Tomotaka Jitsukawa   +2 more
wiley   +1 more source

A Good Life in Old Age: Accommodating Elderly Patients\u27 Values and Motivations in the Thai Healthcare System [PDF]

open access: yes, 2016
People over age sixty-five are the fastest growing segment of the population in most developed and developing nations and their healthcare problems are placing strains on healthcare systems.
Marinucci, Jennie Lynn
core   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

open access: yesFEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda   +9 more
wiley   +1 more source

Organizational Strategies for the Adoption of Electronic Medical Records: Toward an Understanding of Outcome Variation in Nursing Homes [PDF]

open access: yes, 2009
[Excerpt] An important element in president-elect Obama\u27s economic stimulus proposal is his plan to invest a significant proportion of federal dollars in installing electronic medical records (EMR) in U.S. healthcare institutions.
Avgar, Ariel C   +2 more
core   +1 more source

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