Results 141 to 150 of about 107,517 (316)

Multidomain Healthy-Age Programme. Recomendations for Healthy Ageing: On Behalf of the Healthy-Age Network

, 2021
El envejecimiento es un proceso natural asociado a un declive que repercute en un mayor riesgo de padecer discapacidad física y cognitiva, y/o afección emocional y social. En consecuencia, diversos estudios muestran los múltiples beneficios de los programas de entrenamiento multicomponente.
Marcos Pardo, Pablo Jorge, González Gálvez, Noelia, Vaquero Cristóbal, Raquel, Sagarra Romero, Lucía, López Vivancos, Abraham, Velázquez Díaz, Daniel, Gea García, Gemma María, Ponce González, Jesús Gustavo, Esteban Cornejo, Irene, Jiménez Pavón, David, Carbonell Baeza, Ana   +10 more
openaire   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Mitochondrial Translation Inhibition Triggers an Rst2-Controlled Transcriptional Reprogramming of Carbon Metabolism in Stationary-Phase Cells of Fission Yeast

Biomolecules
Mitochondria possess their own genome, which encodes subunits of the electron transport chain, rendering mitochondrial protein translation essential for cellular energy metabolism.
Ying Luo, Shaimaa Hassan, Saniya Raut, Jürg Bähler   +3 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Healthy ageing begins with a healthy lifestyle

eBioMedicine, 2023
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

A randomized controlled feasibility study of a Nintendo RingFit-based exercise program to improve balance and muscle strength in community-dwelling older adults with a history of falls [PDF]

Healthy Ageing Conference 2023, Hong Kong, 26-27 October 2023202406 bcwhNot applicableOthersUndergraduate Research and Innovation Scheme (URIS), The Hong Kong Polytechnic UniversityCopyright retained by ...
Chan, SK, Chan, CK, Chan, WL, Chan, WLS, Chan, HW, Chan, LW   +5 more
core  

Fostering healthy cognitive ageing in people living with HIV

Prevalence and incidence of HIV among people aged 50 years and older continue to rise worldwide, generating increasing awareness among care providers, scientists, and the HIV community about the importance of brain health in older adults with HIV.
Howard, Chris, Njjeri, Priscilla, Wong, Pui Li, Rajasuriar, Reena, Power, Christopher, Moore, Steven P, Nyamayaro, Primrose, Brew, Bruce J, Robbins, Reuben N, Daken, Kirstie, Bruning, Jane, Vera, Jaime, Aung, Htein Linn, Muñoz-Moreno, Jose A, Ferraris, Christopher M, Goodkin, Karl, Ellis, Ronald J, Levin, Jules, Hasmukharay, Kejal, Rourke, Sean B, Rule, John, Trunfio, Mattia, Costello, Jane, Heaton, Robert, Woods, Steven P, Letendre, Scott, Gouse, Hetta, Mullens, Amy B, NeuroHIV and Aging Advocacy Group, Taylor, Jeff, Cysique, Lucette A, Wright, Edwina   +31 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Development of Malaysian-MIND diet scores for prediction of mild cognitive impairment among older adults in Malaysia

BMC Geriatrics
Background Mild Cognitive impairment (MCI) is a pre-demented state in the elderly populace. The Mediterranean & Dietary Approaches to Stop Hypertension (DASH) Intervention for Neurodegenerative Delay (MIND) diet has shown promise in reducing the risk of ...
Muhamad Mustaqim M Zapawi, Yee Xing You, Suzana Shahar, Mohd Razif Shahril, Nurul Fatin Malek Rivan, Nik Nur Izzati Nik Mohd Fakhruddin, Anastasia Xin Wei Yap   +6 more
doaj   +1 more source