Results 21 to 30 of about 107,517 (316)

Healthy ageing: ageing safely [PDF]

European Heart Journal Supplements, 2001
The population of the developed world is steadily ageing. In the European Union, approximately 22% of persons are over 60 years of age and this is projected to increase to more than 27% by the year 2020. This has major implications for health care resources and the productive workforce. Ageing is accompanied by a decline in the physiological reserve of
openaire   +2 more sources

Ethnic and Gender Disparities in Healthy Ageing among People 50 Years and Older in South Africa

, 2021
Objective: this study aimed to determine the prevalence and correlates of healthy ageing in older adults living in the community in South Africa. Methods: the cross-sectional sample consisted of 3734 individuals (≥50 years) from the cross-sectional South
Karl Peltzer, Supa Pengpid
core   +1 more source

Genome‐wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling

Molecular Systems Biology, 2011
FoxO transcription factors, inhibited by insulin/insulin‐like growth factor signalling (IIS), are crucial players in numerous organismal processes including lifespan.
Nazif Alic, T Daniel Andrews, Maria E Giannakou, Irene Papatheodorou, Cathy Slack, Matthew P Hoddinott, Helena M Cochemé, Eugene F Schuster, Janet M Thornton, Linda Partridge   +9 more
doaj   +1 more source

A parthenogenetic quasi-program causes teratoma-like tumors during aging in wild-type C. elegans

npj Aging and Mechanisms of Disease, 2018
Aging: Runaway programs are a cause of aging The main cause of disease worldwide is aging, a process long suspected to result from damage accumulation.
Hongyuan Wang, Yuan Zhao, Marina Ezcurra, Alexandre Benedetto, Ann F. Gilliat, Josephine Hellberg, Ziyu Ren, Evgeniy R. Galimov, Trin Athigapanich, Johannes Girstmair, Maximilian J. Telford, Colin T. Dolphin, Zhizhou Zhang, David Gems   +13 more
doaj   +1 more source

Independent glial subtypes delay development and extend healthy lifespan upon reduced insulin-PI3K signalling

BMC Biology, 2020
Background The increasing age of global populations highlights the urgent need to understand the biological underpinnings of ageing. To this end, inhibition of the insulin/insulin-like signalling (IIS) pathway can extend healthy lifespan in diverse ...
Nathaniel S. Woodling, Arjunan Rajasingam, Lucy J. Minkley, Alberto Rizzo, Linda Partridge   +4 more
doaj   +1 more source

Relationship of muscle function to circulating myostatin, follistatin and GDF11 in older women and men

BMC Geriatrics, 2018
Background Myostatin, its inhibitor follistatin, and growth/differentiation factor 11 (GDF11) have been proposed as factors that could potentially modify biological aging.
Elizaveta Fife, Joanna Kostka, Łukasz Kroc, Agnieszka Guligowska, Małgorzata Pigłowska, Bartłomiej Sołtysik, Agnieszka Kaufman-Szymczyk, Krystyna Fabianowska-Majewska, Tomasz Kostka   +8 more
doaj   +1 more source

Fall awareness behaviour and its associated factors among community dwelling older adults

BMC Geriatrics, 2021
Background Falls are one of the major causes of mortality and morbidity in older adults. However, despite adoption of prevention strategies, the number of falls in older adults has not declined.
Jing Wen Goh, Devinder Kaur Ajit Singh, Normala Mesbah, Anis Afifa Mohd Hanafi, Adlyn Farhana Azwan   +4 more
doaj   +1 more source

The role of local radio in promoting creative engagement for healthy ageing

, 2021
To identify and critique literature on the links between public service local radio promoting creative engagement for healthy ageing in order to better understand the potential for public health agendas.
Vella-Burrows, T., Ewbank, N., Philips, J.   +2 more
core   +1 more source

Improving Electronic Health Record (EHR) data linkages for identifying Aged Care Residents through publicly available data

International Journal of Population Data Science
Introduction Accurate identification of Aged Care residents accessing hospital services is challenging due to multiple hospital Electronic Health Record (EHR) systems and entry points resulting in inconsistent addresses and coding.
Tanya Ravipati, Richard Beare, Velandai Srikanth, Alison Carver, Lei Huang, Rashwinder Dhillon, Nadine E Andrew   +6 more
doaj   +1 more source

Heterogeneity in Healthy Aging [PDF]

The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2013
For a surprisingly large segment of the older population, chronological age is not a relevant marker for understanding, measuring, or experiencing healthy aging. Using the 2003 Medical Expenditure Panel Survey and the 2004 Health and Retirement Study to examine the proportion of Americans exhibiting five markers of health and the variation in health ...
David J, Lowsky, S Jay, Olshansky, Jay, Bhattacharya, Dana P, Goldman   +3 more
openaire   +2 more sources