Results 31 to 40 of about 91,653 (266)

Healthy ageing: ageing safely [PDF]

open access: yesEuropean Heart Journal Supplements, 2001
The population of the developed world is steadily ageing. In the European Union, approximately 22% of persons are over 60 years of age and this is projected to increase to more than 27% by the year 2020. This has major implications for health care resources and the productive workforce. Ageing is accompanied by a decline in the physiological reserve of
openaire   +2 more sources

Heterogeneity in Healthy Aging [PDF]

open access: yesThe Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2013
For a surprisingly large segment of the older population, chronological age is not a relevant marker for understanding, measuring, or experiencing healthy aging. Using the 2003 Medical Expenditure Panel Survey and the 2004 Health and Retirement Study to examine the proportion of Americans exhibiting five markers of health and the variation in health ...
David J, Lowsky   +3 more
openaire   +2 more sources

Plasma lipidome is dysregulated in Alzheimer’s disease and is associated with disease risk genes

open access: yesTranslational Psychiatry, 2021
Lipidomics research could provide insights of pathobiological mechanisms in Alzheimer’s disease. This study explores a battery of plasma lipids that can differentiate Alzheimer’s disease (AD) patients from healthy controls and determines whether lipid ...
Yue Liu   +8 more
doaj   +1 more source

Healthy aging in China [PDF]

open access: yesThe Journal of the Economics of Ageing, 2014
China has aged rapidly and the rate is accelerating in decades to come. We review positive and negative forces for healthy aging in China now and in the future. The most positive force is the spectacular growth in education over time especially for Chinese women, which should improve all dimensions of cognitive and physical health and eliminate vast ...
James P, Smith   +2 more
openaire   +2 more sources

Genome‐wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling

open access: yesMolecular Systems Biology, 2011
FoxO transcription factors, inhibited by insulin/insulin‐like growth factor signalling (IIS), are crucial players in numerous organismal processes including lifespan.
Nazif Alic   +9 more
doaj   +1 more source

A parthenogenetic quasi-program causes teratoma-like tumors during aging in wild-type C. elegans

open access: yesnpj Aging and Mechanisms of Disease, 2018
Aging: Runaway programs are a cause of aging The main cause of disease worldwide is aging, a process long suspected to result from damage accumulation.
Hongyuan Wang   +13 more
doaj   +1 more source

Relationship of muscle function to circulating myostatin, follistatin and GDF11 in older women and men

open access: yesBMC Geriatrics, 2018
Background Myostatin, its inhibitor follistatin, and growth/differentiation factor 11 (GDF11) have been proposed as factors that could potentially modify biological aging.
Elizaveta Fife   +8 more
doaj   +1 more source

Improving Electronic Health Record (EHR) data linkages for identifying Aged Care Residents through publicly available data

open access: yesInternational Journal of Population Data Science
Introduction Accurate identification of Aged Care residents accessing hospital services is challenging due to multiple hospital Electronic Health Record (EHR) systems and entry points resulting in inconsistent addresses and coding.
Tanya Ravipati   +6 more
doaj   +1 more source

Independent glial subtypes delay development and extend healthy lifespan upon reduced insulin-PI3K signalling

open access: yesBMC Biology, 2020
Background The increasing age of global populations highlights the urgent need to understand the biological underpinnings of ageing. To this end, inhibition of the insulin/insulin-like signalling (IIS) pathway can extend healthy lifespan in diverse ...
Nathaniel S. Woodling   +4 more
doaj   +1 more source

Fall awareness behaviour and its associated factors among community dwelling older adults

open access: yesBMC Geriatrics, 2021
Background Falls are one of the major causes of mortality and morbidity in older adults. However, despite adoption of prevention strategies, the number of falls in older adults has not declined.
Jing Wen Goh   +4 more
doaj   +1 more source

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