Results 41 to 50 of about 107,517 (316)

Tissue-specific transcriptome profiling of Drosophila reveals roles for GATA transcription factors in longevity by dietary restriction

open access: yesnpj Aging and Mechanisms of Disease, 2018
Author summary Ageing human populations present a huge societal challenge, providing motivation to find ways to improve health in old age. Dietary restriction (DR), is one way to improve late-life health of animals from worms to mammals, and perhaps ...
Adam J. Dobson   +6 more
doaj   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa   +8 more
wiley   +1 more source

Two forms of death in ageing Caenorhabditis elegans

open access: yesNature Communications, 2017
Despite its wide use in ageing research, the contribution of specific age-associated pathologies toC. elegansmortality is not well understood. Here the authors identify two types of death in worms, with either a swollen or a shrunken pharynx, that are ...
Yuan Zhao   +12 more
doaj   +1 more source

Melatonin and healthy aging

open access: yes, 2021
Preservation of a robust circadian rhythmicity (particulsarly of the sleep/wake cycle), a proper nutrition and adequate physical exercise are key elements for healthy aging. Aging comes along with circadian alteration, e.g. a disrupted sleep and inflammation, that leads to metabolic disorders.
openaire   +2 more sources

Healthy Aging in Cities [PDF]

open access: yesJournal of Urban Health, 2008
In the coming decades the global population will urbanize and age at high rates. Today half of the worlds populations lives in cities.1 By 2030 that proportion will rise to 60% and urbanization will occur most greatly in developing countries. At the same time the worlds population aged 60 and over will double from 11% to 22% by 2050 and that growth ...
openaire   +2 more sources

Healthy aging in China [PDF]

open access: yesThe Journal of the Economics of Ageing, 2014
China has aged rapidly and the rate is accelerating in decades to come. We review positive and negative forces for healthy aging in China now and in the future. The most positive force is the spectacular growth in education over time especially for Chinese women, which should improve all dimensions of cognitive and physical health and eliminate vast ...
James P, Smith   +2 more
openaire   +2 more sources

Professional competences to promote healthy ageing across the lifespan: a scoping review [PDF]

open access: yes, 2023
As societies age, the development of resources and strategies that foster healthy ageing from the beginning of life become increasingly important. Social and healthcare professionals are key agents in this process; therefore, their training needs to be ...
Scherpenseel, Meike van   +24 more
core   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

The effectiveness and user experience of a computer-based training programme on everyday activities for older adults : a mixed method study

open access: yes, 2023
AIMS Older adults may experience cognitive deterioration, which impacts their independence in everyday activities. This study aims to examine the effectiveness and user experience of a computer-based cognitive training program called Enhancing Memory in ...
Bissett, Michelle   +3 more
core  

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

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