Results 61 to 70 of about 339,619 (303)

Incidence and multidimensional predictors of occasional and recurrent falls among Malaysian community‐dwelling older persons

BMC Geriatrics, 2021
Background Falls incidence rate and comprehensive data on factors that predict occasional and repeated falls from large population-based studies are scarce. In this study, we aimed to determine the incidence of falls and identify predictors of occasional
Theng Choon Ooi, Devinder Kaur Ajit Singh, Suzana Shahar, Nor Fadilah Rajab, Divya Vanoh, Razinah Sharif, Maw Pin Tan   +6 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Healthy Aging

Journal of Karnali Academy of Health Sciences, 2023
Rapid population aging is a characteristic of the 21st century, regardless of a nation’s level of development. An aging global population results in a burden in medical and social demographic problems worldwide. Addressing this problem is the highest priority for the care of the aging population worldwide.
openaire   +2 more sources

Oxidative stress and epigenetic regulation in ageing and age-related diseases [PDF]

, 2013
Recent statistics indicate that the human population is ageing rapidly. Healthy, but also diseased, elderly people are increasing. This trend is particularly evident in Western countries, where healthier living conditions and better cures are available ...
Cencioni, Chiara, Gaetano, Carlo, Mai, Antonello, Martelli, Fabio, Spallotta, Francesco, Valente, Sergio, Zeiher, Andreas Michael   +6 more
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

The implementation of a perioperative medicine for older people undergoing surgery service: a qualitative case study

BMC Health Services Research
Background The international scale and spread of evidence-based perioperative medicine for older people undergoing surgery (POPS) services has not yet been fully realised.
Margot E Lodge, Jugdeep Dhesi, David JH Shipway, Philip Braude, Catherine Meilak, Judith Partridge, Nadine E Andrew, Velandai Srikanth, Darshini R Ayton, Chris Moran   +9 more
doaj   +1 more source

Associations between frailty trajectories and frailty status and adverse outcomes in community‐dwelling older adults

Journal of Cachexia, Sarcopenia and Muscle, 2022
Background The association between frailty and adverse outcomes has been clearly defined. Frailty is associated with age, but different frailty evolution patterns might determine the incidence of adverse outcomes at older ages.
Alejandro Álvarez‐Bustos, Jose Antonio Carnicero‐Carreño, Juan Luis Sanchez‐Sanchez, Francisco Javier Garcia‐Garcia, Cristina Alonso‐Bouzón, Leocadio Rodríguez‐Mañas   +5 more
doaj   +1 more source

Post‐GWAS Polygenic Risk Score: Utility and Challenges

JBMR Plus, 2020
Over the past decade, through genome‐wide association studies, more than 300 genetic variants have been identified to be associated with either BMD or fracture risk.
Tuan V Nguyen, John A Eisman
doaj   +1 more source

Role of sarcopenia in the frailty transitions in older adults: a population‐based cohort study

Journal of Cachexia, Sarcopenia and Muscle, 2022
Background Frailty and sarcopenia are age‐associated syndromes that have been associated with the risk of several adverse events, mainly functional decline and death, that usually coexist.
Alejandro Álvarez‐Bustos, Jose Antonio Carnicero‐Carreño, Betty Davies, Francisco Javier Garcia‐Garcia, Fernando Rodríguez‐Artalejo, Leocadio Rodríguez‐Mañas, Cristina Alonso‐Bouzón   +6 more
doaj   +1 more source

Australian households and families [PDF]

, 2013
The size of Australian households and the forms they take have changed in profound ways across the years. These trends result from the interaction of many factors; for example, the increasing size and ageing of the population, along with an extended ...

core   +1 more source