Results 21 to 30 of about 11,242,010 (306)

Gut microbiome pattern reflects healthy aging and predicts survival in humans

open access: yesNature Metabolism, 2021
The gut microbiome has important effects on human health, yet its importance in human ageing remains unclear. In the present study, we demonstrate that, starting in mid-to-late adulthood, gut microbiomes become increasingly unique to individuals with age.
T. Wilmanski   +20 more
semanticscholar   +1 more source

Evaluation of the usefulness of a paper–pencil group cognitive assessment for older adults in the community

open access: yesBMC Public Health, 2023
Background As the older population increases, the need for early detection of cognitive decline is also increasing. In this study, we examined whether our paper–pencil type group examination for cognitive assessment (PAPLICA) could detect the effects of ...
Daisuke Cho   +10 more
doaj   +1 more source

Gut microbiome in healthy aging versus those associated with frailty

open access: yesGut microbes, 2023
As the proportion of older people in the world’s population steadily increases, there is an urgent need to identify ways to support healthy aging. The gut microbiome has been proposed to be involved in aging-related diseases and has become an attractive ...
M. Lim, Young-Do Nam
semanticscholar   +1 more source

Healthy Ageing

open access: yesDer Gynäkologe, 2019
Gezond ouder worden, hoe doen mensen dat? Bij Healthy ageing staat het gedrag dat bijdraagt aan een zo gezond mogelijk leven centraal. Het gaat hierbij vooral om het bevorderen van zelfredzaamheid en versterken van gezond gedrag. Bij professionals is er een groeiende behoefte aan inzichten over gezond ouder worden en aan interventies die dat ...
Wiekens, Carina, Jukema, Jan S.
  +6 more sources

Role of osteogenic Dickkopf-1 in bone remodeling and bone healing in mice with type I diabetes mellitus

open access: yesScientific Reports, 2021
Type 1 diabetes mellitus (T1DM) is associated with low bone mass and a higher risk for fractures. Dickkopf-1 (Dkk1), which inhibits Wnt signaling, osteoblast function, and bone formation, has been found to be increased in the serum of patients with T1DM.
Nick Hildebrandt   +7 more
doaj   +1 more source

Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging

open access: yesNature Aging, 2023
The concept of aging is complex, including many related phenotypes such as healthspan, lifespan, extreme longevity, frailty and epigenetic aging, suggesting shared biological underpinnings; however, aging-related endpoints have been primarily assessed ...
Daniel B. Rosoff   +8 more
semanticscholar   +1 more source

Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank

open access: yesScientific Reports, 2021
Here, we investigated the genetics of weighted functional brain network graph theory measures from 18,445 participants of the UK Biobank (44–80 years). The eighteen measures studied showed low heritability (mean h2 SNP = 0.12) and were highly genetically
Heidi Foo   +6 more
doaj   +1 more source

Attitudes related to technology for active and healthy aging in a national multigenerational survey

open access: yesNature Aging, 2023
Research is needed to understand attitudes toward and adoption of the broad range of technologies available to support active and healthy aging in different generations.
J. Offerman   +4 more
semanticscholar   +1 more source

Nitric oxide-induced ribosome collision activates ribosomal surveillance mechanisms

open access: yesCell Death and Disease, 2023
Impairment of protein translation can cause stalling and collision of ribosomes and is a signal for the activation of ribosomal surveillance and rescue pathways.
Laura Ryder   +8 more
doaj   +1 more source

Healthy ageing: ageing safely [PDF]

open access: yesEuropean Heart Journal Supplements, 2001
The population of the developed world is steadily ageing. In the European Union, approximately 22% of persons are over 60 years of age and this is projected to increase to more than 27% by the year 2020. This has major implications for health care resources and the productive workforce. Ageing is accompanied by a decline in the physiological reserve of
openaire   +2 more sources

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