Results 31 to 40 of about 11,242,010 (306)

Toward an improved definition of a healthy microbiome for healthy aging

Nature Aging, 2022
The gut microbiome is a modifier of disease risk because it interacts with nutrition, metabolism, immunity and infection. Aging-related health loss has been correlated with transition to different microbiome states.
T. Ghosh, F. Shanahan, P. O’Toole
semanticscholar   +1 more source

A Potential Probiotic Lactobacillus plantarum JBC5 Improves Longevity and Healthy Aging by Modulating Antioxidative, Innate Immunity and Serotonin-Signaling Pathways in Caenorhabditis elegans

Antioxidants, 2022
Since the hypothesis of Dr. Elie Metchnikoff on lactobacilli-mediated healthy aging, several microbes have been reported to extend the lifespan with different features of healthy aging. However, a microbe affecting diverse features of healthy aging is of
Arun Kumar, T. Joishy, Santanu Das, M. C. Kalita, Ashis K. Mukherjee, M. Khan   +5 more
semanticscholar   +1 more source

Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial

Nature Aging, 2023
The geroscience hypothesis proposes that therapy to slow or reverse molecular changes that occur with aging can delay or prevent multiple chronic diseases and extend healthy lifespan1–3.
R. Waziry, C. Ryan, D. Corcoran, K. Huffman, M. Kobor, M. Kothari, G. Graf, V. Kraus, W. Kraus, D. Lin, C. Pieper, M. Ramaker, M. Bhapkar, S. Das, L. Ferrucci, W. J. Hastings, M. Kebbe, D. Parker, S. Racette, I. Shalev, B. Schilling, D. Belsky   +21 more
semanticscholar   +1 more source

Healthy Aging [PDF]

Zeitschrift für Orthomolekulare Medizin, 2020
ZusammenfassungDie Alterung von Körper und Gehirn wird durch mediterrane Ernährung und bedarfsgerechte Substitution von EPA und DHA in Form von Fisch-/Algenöl verlangsamt. Studien belegen die positive Wirkung einer ausreichenden Versorgung mit ω-3-Fettsäuren auf Alterungsprozesse u. a.
  +5 more sources

Healthy Aging and Dietary Patterns

Nutrients, 2022
A number of factors contribute to the complex process of aging, which finally define whether someone will or not develop age-associated chronic diseases in late life.
L. Dominguez, N. Veronese, Eleonora Baiamonte, M. Guarrera, Angela Parisi, Chiara Ruffolo, Federica Tagliaferri, M. Barbagallo   +7 more
semanticscholar   +1 more source

Skeletal endocrinology: where evolutionary advantage meets disease

Bone Research, 2021
The regulation of whole-body homeostasis by the skeleton is mediated by its capacity to secrete endocrine signaling molecules. Although bone-derived hormones confer several adaptive benefits, their physiological functions also involve trade-offs, thus ...
Nikolai Jaschke, Wolfgang Sipos, Lorenz C. Hofbauer, Tilman D. Rachner, Martina Rauner   +4 more
doaj   +1 more source

Effects of adipocyte-specific Dkk1 deletion on bone homeostasis and obesity-induced bone loss in male mice

Endocrine Connections, 2023
The link between obesity and low bone strength has become a significant medical concern. The canonical Wnt signaling pathway is a key regulator of mesenchymal stem cell differentiation into either osteoblasts or adipocytes with active Wnt signaling ...
Souad Daamouch, Sylvia Thiele, Lorenz Hofbauer, Martina Rauner   +3 more
doaj   +1 more source

Functional dedifferentiation of associative resting state networks in older adults – A longitudinal study

NeuroImage, 2020
Healthy aging is associated with weaker functional connectivity within resting state brain networks and stronger functional interaction between these networks.
Brigitta Malagurski, Franziskus Liem, Jessica Oschwald, Susan Mérillat, Lutz Jäncke   +4 more
doaj   +1 more source

Mediterranean Diet In Healthy Aging

The Journal of Nutrition, Health & Aging, 2021
The World elderly population is expected to double before 2050. Unhealthy habits and unhealthy lifestyles are commonly associated with age-related diseases or their worsening.
E. Mazza, Y. Ferro, R. Pujia, R. Mare, S. Maurotti, T. Montalcini, A. Pujia   +6 more
semanticscholar   +1 more source

Interventions on Gut Microbiota for Healthy Aging

Cells, 2022
In recent years, the improvement in health and social conditions has led to an increase in the average lifespan. Since aging is the most important risk factor for the majority of chronic human diseases, the development of therapies and intervention to ...
Sabrina Donati Zeppa, D. Agostini, Fabio Ferrini, Marco Gervasi, E. Barbieri, A. Bartolacci, G. Piccoli, R. Saltarelli, P. Sestili, V. Stocchi   +9 more
semanticscholar   +1 more source