Results 61 to 70 of about 933,857 (297)

Healthy Aging

Journal of Karnali Academy of Health Sciences, 2023
Rapid population aging is a characteristic of the 21st century, regardless of a nation’s level of development. An aging global population results in a burden in medical and social demographic problems worldwide. Addressing this problem is the highest priority for the care of the aging population worldwide.
openaire   +2 more sources

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard, Hital Patel, Paula C. Vincent, Justine Kahn, Kira Bona, Thai Hoa Tran, Elisa M. Rodriguez, Kristopher Attwood, Kara M. Kelly   +8 more
wiley   +1 more source

Lagged Coupled Changes Between White Matter Microstructure and Processing Speed in Healthy Aging: A Longitudinal Investigation

Frontiers in Aging Neuroscience, 2019
Age-related differences in white matter (WM) microstructure have been linked to lower performance in tasks of processing speed in healthy older individuals. However, only few studies have examined this link in a longitudinal setting. These investigations
Jessica Oschwald, Susan Mérillat, Franziskus Liem, Christina Röcke, Mike Martin, Mike Martin, Lutz Jäncke, Lutz Jäncke   +7 more
doaj   +1 more source

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase

iScience, 2022
Summary: Most tumor cells reactivate telomerase to ensure unlimited proliferation, whereas the expression of human telomerase reverse transcriptase (hTERT) is tightly regulated and rate-limiting for telomerase activity maintenance.
Zhifen Zhou, Yujing Li, Huimin Xu, Xiaowei Xie, Zibin He, Song Lin, Ruofei Li, Shouheng Jin, Jun Cui, Hai Hu, Feng Liu, Su Wu, Wenbin Ma, Zhou Songyang   +13 more
doaj   +1 more source

TLR-6 SNP P249S is associated with healthy aging in nonsmoking Eastern European Caucasians - A cohort study [PDF]

, 2016
Background To investigate mechanisms that determine healthy aging is of major interest in the modern world marked by longer life expectancies. In addition to lifestyle and environmental factors genetic factors also play an important role in aging ...
Bustami, Jasmin, Hamann, Lutz, Iakoubov, Leonid, Mossakowska, Malgorzata, Puzianowska-Kuznicka, Monika, Schumann, Ralf R., Szwed, Malgorzata   +6 more
core   +2 more sources

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source

An Exploration of the Communication Dynamics of the Hard-to-Reach: Considering Disintegration of a Communication Infrastructure in Old Age

International Journal of Communication, 2023
Health is influenced by social interactions and resources afforded through connections in our homes, neighborhoods, and communities. As people age, health challenges increase while their social networks decrease.
Carrie Leach, Julie M. Novak, Thomas B. Jankowski, Sandie Pierce, Pam Lapan   +4 more
doaj   +2 more sources

Association of ART regimen and adherence to viral suppression: an observational study of a clinical population of people with HIV

AIDS Research and Therapy
Adherence to antiretroviral therapy (ART) is essential for the effective management of HIV, which includes keeping the HIV viral load undetectable. This study aimed to determine whether certain ART medications are more “forgiving” of poor adherence in ...
Jasmine A. Manalel, Jennifer E. Kaufman, Yiyi Wu, Ethan Fusaris, Arlene Correa, Jerome Ernst, Mark Brennan-Ing   +6 more
doaj   +1 more source

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

Rejuvenation by cell reprogramming: A new horizon in gerontology [PDF]

, 2018
The discovery of animal cloning and subsequent development of cell reprogramming technology were quantum leaps as they led to the achievement of rejuvenation by cell reprogramming and the emerging view that aging is a reversible epigenetic process. Here,
Brown, Oscar Alfredo, Canatelli Mallat, Martina, Chiavellini, Priscila, Goya, Rodolfo Gustavo, Hereñú, Claudia Beatriz, Lehmann, Marianne   +5 more
core   +2 more sources