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Is clonal haematopoiesis the missing link between lupus and cardiovascular disease? [PDF]
Shamsi A +6 more
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Germline and somatic variants in DNMT3A and other clonal haematopoiesis of indeterminate potential genes contribute to pulmonary arterial hypertension. [PDF]
Al-Qazazi R +23 more
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Organ-on-a-chip platforms for disease modeling and in vitro diagnostic applications. [PDF]
Hao P, Deng J, Xu J.
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Clinical Outcomes of Concurrent Impella-Assisted High-Risk PCI and TAVR in Patients With Complex Coronary Artery Disease and Severe Aortic Stenosis. [PDF]
Rivera FB +5 more
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Assessing the influence of perfusion on cardiac microtissue maturation: A heart-on-chip platform embedding peristaltic pump capabilities [PDF]
Heart-on-chip is an unprecedented technology for recapitulating key biochemical and biophysical cues in cardiac pathophysiology. Several designs have been proposed to improve its ability to mimic the native tissue and establish it as a reliable research ...
Roberta Visone, Francisco Vasques-Nóvoa
exaly +2 more sources
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Sensors in heart-on-a-chip: A review on recent progress
Talanta, 2020Drug-induced cardiotoxicity is a major problem in drug discovery. Many approaches to efficient drug screening have been developed, including animal testing in vivo and cell testing in vitro. However, due to intrinsic difference between species, animal-based toxicity testing cannot comprehensively determine the potential side effects in subsequent human
Byung-Soo Kim +2 more
exaly +3 more sources
Heart-on-a-chip based on stem cell biology
Biosensors and Bioelectronics, 2016Heart diseases are one of the main causes of death around the world. The great challenge for scientists is to develop new therapeutic methods for these types of ailments. Stem cells (SCs) therapy could be one of a promising technique used for renewal of cardiac cells and treatment of heart diseases.
Elzbieta Jastrzebska, Iwona Jesion
exaly +3 more sources

