Results 251 to 260 of about 132,211,819 (268)

Heart-on-a-chip based on machine vision and artificial intelligence

The research and development of cardiac drugs often focus on drug efficacy and side effects. However, traditional drug detection model of two-dimensional cell culture in Petri dish can not meet the need of drug industry with lower cost and quick time. Heart-on-a-chip (HOC) as an alternative physiological model to simulate human heart microenvironment ...
Xin Ma, Natan Barros, Ji Zhao
openaire   +1 more source

Heart-on-a-chip for drug screening and disease modeling

La technologie cœur sur puce (HOC) s’est imposée comme une approche puissante pour reproduire in vitro les propriétés structurelles, mécaniques et fonctionnelles du cœur natif, permettant la création de plateformes physiologiquement pertinentes pour le criblage pharmacologique et la modélisation des maladies.
openaire   +1 more source

A Heart-on-a-Chip Microdevice with Aligned Fibers for Cardiotoxicity Assessment

Abstract Background and Objectives Cardiovascular cells differentiated from human induced pluripotent stem cells (iPSCs), including cardiomyocytes, are valuable for evaluating human cardiac pharmacology and toxicity.
Kozue Murata, Mosha Abulaiti, Rio Okama, Kensuke Kato, Yo Tanaka, Hidetoshi Masumoto   +5 more
openaire   +1 more source

Design and Simulation of an Oxygen Gradient Generator for Heart-on-a-Chip

2023 30th National and 8th International Iranian Conference on Biomedical Engineering (ICBME), 2023
Mahya Mosayebzadeh, Sogol Fathi, Ali Abouei Mehrizi   +2 more
openaire   +1 more source

Heart-on-a-chip

2020
Gaudriault, Pierre, Fassini, Dario, Homs-Corbera, Antoni   +2 more
openaire   +1 more source

Engineering Cardiobundles with Dynamic Microenvironmental Control as Advanced Cardiac Modeling for Heart‐on‐a‐Chip

Small
AbstractAdvancing cardioprotective therapies requires physiologically relevant preclinical models, yet conventional approaches—including 2D cell cultures, 3D spheroids, and animal models—fail to fully recapitulate the structural complexity and dynamic microenvironment of native cardiac tissue, often facing species‐specific discrepancies and ethical ...
Lanlan Hu, Mingying Han, Jiaxin Yang, Liu Yu, Maoyu Qin, Jie Xu, Hao Zhang, Xinyi Chen, Yinmu Li, Hongfang Meng, Sitian Liu, Yaobin Wu, Dingli Xu, Ling Wang   +13 more
openaire   +2 more sources

Integration of heart-on-a-chip and metabolomics for understanding the toxicity-attenuating effect of ethnomedicinal processing

Phytomedicine
Tiebangchui (TBC), is a well-known traditional Tibetan medicine that coexists with toxicity and effects. Highland barley wine is an effective and unique processing method to reduce TBC's toxic side effects. However, the toxicity reduction mechanism is ambiguous and needs to be explored urgently.
Xinmei, Xu, Yue, Liu, Shufu, Yu, Suet, Cheung, Mengyang, Cui, Yongjian, Ai, Yi, Zhang, Qionglin, Liang   +7 more
openaire   +2 more sources

Synthesizing a Heart Rate Analyzer Chip QRS

International Journal of Advancements in Computing Technology, 2013
Saed Abed -, Ahmad AlKhasawneh -, Sahel Alouneh -   +2 more
openaire   +1 more source

Heart-on-chips screening based on photonic crystals

Bio-Design and Manufacturing, 2020
Yixuan Shang, Zhuohao Zhang, Zhuoyue Chen   +2 more
exaly  

Heart-on-a-chip platforms and biosensor integration for disease modeling and phenotypic drug screening

Biosensors and Bioelectronics, 2023
Sean V Murphy, Deok-Ho Kim, Su Ryon Shin
exaly