Results 1 to 10 of about 157,184 (300)

Piscine Orthoreovirus-1 Isolates Differ in Their Ability to Induce Heart and Skeletal Muscle Inflammation in Atlantic Salmon (Salmo salar) [PDF]

Pathogens, 2020
Piscine orthoreovirus 1 (PRV-1) is the causative agent of heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). The virus is widespread in Atlantic salmon and was present in Norway long before the first description of ...
Øystein Wessel, Elisabeth F. Hansen, Maria K. Dahle, Marta Alarcon, Nina A. Vatne, Ingvild B. Nyman, Karen B. Soleim, Kannimuthu Dhamotharan, Gerrit Timmerhaus, Turhan Markussen, Morten Lund, Håvard Aanes, Magnus Devold, Makoto Inami, Marie Løvoll, Espen Rimstad   +15 more
doaj   +7 more sources

Heart and skeletal muscle inflammation (HSMI) disease diagnosed on a British Columbia salmon farm through a longitudinal farm study. [PDF]

PLoS ONE, 2017
Heart and skeletal muscle inflammation (HSMI) is an emerging disease of marine-farmed Atlantic Salmon (Salmo salar), first recognized in 1999 in Norway, and later also reported in Scotland and Chile.
Emiliano Di Cicco, Hugh W Ferguson, Angela D Schulze, Karia H Kaukinen, Shaorong Li, Raphaël Vanderstichel, Øystein Wessel, Espen Rimstad, Ian A Gardner, K Larry Hammell, Kristina M Miller   +10 more
doaj   +7 more sources

Native lamin A/C proteomes and novel partners from heart and skeletal muscle in a mouse chronic inflammation model of human frailty

Frontiers in Cell and Developmental Biology, 2023
Clinical frailty affects ∼10% of people over age 65 and is studied in a chronically inflamed (Interleukin-10 knockout; “IL10-KO”) mouse model. Frailty phenotypes overlap the spectrum of diseases (“laminopathies”) caused by mutations in LMNA. LMNA encodes
Fatima D. Elzamzami, Arushi Samal, Adith S. Arun, Tejas Dharmaraj, Neeti R. Prasad, Alex Rendon-Jonguitud, Lauren DeVine, Jeremy D. Walston, Robert N. Cole, Katherine L. Wilson   +9 more
doaj   +3 more sources

Exercise mitigates IL-27-induced muscle atrophy following myocardial infarction through anti-inflammatory mechanisms [PDF]

Journal of Translational Medicine
Background Skeletal muscle atrophy is a common complication of heart failure, with myocardial infarction (MI) being the primary cause. Yet, the mechanisms linking post-MI cardiac insufficiency to muscle atrophy have remained unclear.
Yuancong Li, Gaosheng Yin, Shuangxiu Li, Qi Zheng, Yongliang Jiang, Changyan Li, Lin Yang, Hao Li, Xingyu Chen, Ping Yang, Lin Sun   +10 more
doaj   +2 more sources

Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study

Frontiers in Medicine, 2023
BackgroundLow muscle mass disproportionately affects people with coronary heart disease compared to healthy controls but is under-researched and insufficiently treated. Inflammation, poor nutrition, and neural decline might contribute to low muscle mass.
Emily James, Emily James, Emily James, Stuart Goodall, Simon Nichols, Simon Nichols, Karen Walker, Sean Carroll, Alasdair F. O’Doherty, Lee Ingle   +9 more
doaj   +1 more source

Dynamics of Polarized Macrophages and Activated CD8+ Cells in Heart Tissue of Atlantic Salmon Infected With Piscine Orthoreovirus-1

Frontiers in Immunology, 2021
Piscine orthoreovirus (PRV-1) infection causes heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). The virus is also associated with focal melanized changes in white skeletal muscle where PRV-1 infection of macrophages ...
Muhammad Salman Malik, Ingvild Berg Nyman, Øystein Wessel, Maria K. Dahle, Espen Rimstad   +4 more
doaj   +1 more source

Exercise Capacity Is Improved by Levosimendan in Heart Failure and Sarcopenia via Alleviation of Apoptosis of Skeletal Muscle

Frontiers in Physiology, 2022
BackgroundPatients suffering from chronic heart failure (CHF) show an increased prevalence of sarcopenia. Levosimendan is an effective drug for the treatment of heart failure, but its effect on sarcopenia is still unclear.
Di Wang, Ming Song, Long-fei Shen, Lu Han, Lu Han, Ping Zhu, Xu Jia, Guo-kai Shang, Yuan Cao, Wei Zhang, Ming Zhong, Zhi-hao Wang, Zhi-hao Wang   +12 more
doaj   +1 more source

The role of nutraceuticals in heart failure muscle wasting as a result of inflammatory activity. The International Lipid Expert Panel (ILEP) Position Paper.

Archives of Medical Science, 2023
Muscle wasting is one of the main causes for exercise intolerance and ventilatory inefficiency in patients with heart failure and a strong predictor of frailty and reduced survival.
Agata Magdalena Bielecka-Dabrowa, Maciej Banach, Andrzej Wittczak, Arrigo FG Cicero, Amani Kallel, Raimondas Kubilius, Dimitri P. Mikhailidis, Amirhossein Sahebkar, Anca Pantea Stoian, Dragos Vinereanu, Peter Edward Penson, Stephan von Haehling   +11 more
doaj   +1 more source

A Spotlight on T Lymphocytes in Duchenne Muscular Dystrophy—Not Just a Muscle Defect

Biomedicines, 2022
The lack of dystrophin in Duchenne muscular dystrophy (DMD) results in membrane fragility resulting in contraction-induced muscle damage and subsequent inflammation.
Chantal A. Coles, Ian Woodcock, Daniel G. Pellicci, Peter J. Houweling   +3 more
doaj   +1 more source

Mineralocorticoid Receptor Signaling in the Inflammatory Skeletal Muscle Microenvironments of Muscular Dystrophy and Acute Injury

Frontiers in Pharmacology, 2022
Duchenne muscular dystrophy (DMD) is a striated muscle degenerative disease due to loss of functional dystrophin protein. Loss of dystrophin results in susceptibility of muscle membranes to damage, leading to muscle degeneration and continuous ...
Zachary M. Howard, Chetan K. Gomatam, Arden B. Piepho, Jill A. Rafael-Fortney   +3 more
doaj   +1 more source