Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
THE CONDUCTING SYSTEM OF THE VERTEBRATE HEART [PDF]
Biological Reviews, 1946 F, DAVIES, E T B, FRANCIS
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Predictive factors of atrioventricular conduction disorders [PDF]
Romanian Medical JournalAtrioventricular conduction disorders represent an alteration in the normal function of the heart’s electrical conduction system, a system that connects the atria and ventricles through the atrio-ventricular node and the His-Purkinje system. Consequently,
Carmen Marina Deutsch +2 more
doaj +1 more source
Nonlinear physics of electrical wave propagation in the heart: a review [PDF]
, 2016 The beating of the heart is a synchronized contraction of muscle cells (myocytes) that are triggered by a periodic sequence of electrical waves (action potentials) originating in the sino-atrial node and propagating over the atria and the ventricles ...
Alonso Muñoz, Sergio +2 more
core +2 more sources
Atrioventricular Node Ablation Combined with Permanent His-Purkinje Conduction System Pacing in Patients with Atrial Fibrillation with Heart Failure: A Systematic Review and Meta-analysis [PDF]
, 2022 Lina wang +3 more
openalex +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
FEBS Open Bio, EarlyView.The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
Indian Journal of AnaesthesiaBackground and Aims: This study aimed to compare the effects of three local anaesthetic (LA) agents, namely bupivacaine, levobupivacaine, and ropivacaine, on the cardiac conduction system as assessed by corrected QT (QTc) and P wave dispersion (PWD ...
Vaishali Agarwal +4 more
doaj +1 more source
Revolutionizing cardiovascular medicine: targeted therapies for the cardiac conduction system
The Journal of Clinical Investigation, 2022 Arrhythmogenic cardiovascular disorders are associated with considerable morbidity and mortality. Whether cardiac conduction disease is caused by genetic defects, procedural perturbations, valvular disease, ischemia, aging, or heart failure, new ...
Daniel J. Garry +2 more
doaj +1 more source
A concise review on the anatomy of the atrioventricular node in mammals [PDF]
The Iranian Journal of Veterinary Science and Technology, 2009 Cardiac conduction system enables the heart to pulsate continuously by producing electric impulse and conducting it. As the anatomical information about cardiac conduction system in human being and other mammals needed in various fields of sciences, such
Abolghassem Nabipour
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Cryothermal Energy Ablation Of Cardiac Arrhythmias 2005: State Of The Art [PDF]
, 2005 At the time of antiarrhythmic surgery, cryothermal energy application by a hand-held probe was used to complement dissections and resections and permanently abolish the arrhythmogenic substrate.
De Ponti, Roberto
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