Results 61 to 70 of about 188,628 (354)

Conduction System Pacing Versus Conventional Cardiac Resynchronization Therapy in Congenital Heart Disease [PDF]

, 2022
Jeremy P. Moore, Natasja M.S. de Groot, Matthew O’Connor, Daniel Cortez, Jonathan K. Su, Austin Burrows, Kevin Shannon, Edward T. O’Leary, Maully J. Shah, Paul Khairy, Joseph Atallah, Tom Wong, Michael S. Lloyd, Yannick J.H.J. Taverne, Anne M. Dubin, Jens Cosedis Nielsen, Reinder Evertz, Richard J. Czosek, Malini Madhavan, Philip M. Chang, Alper Aydın, Óscar Cano   +21 more
openalex   +1 more source

Bidirectional ventricular tachycardia in cardiac sarcoidosis. [PDF]

, 2016
A 73-year-old man with history of pulmonary sarcoidosis was found to have runs of non-sustained bidirectional ventricular tachycardia (BVT) with two different QRS morphologies on a Holter monitor.
Benjamin, Mina M, Field, Michael E, Hayes, Kevin, Hoffmayer, Kurt S, Scheinman, Melvin M   +4 more
core   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Development of the Cardiac Conduction System and the Possible Relation to Predilection Sites of Arrhythmogenesis

The Scientific World Journal, 2008
The cardiac conduction system (CCS) encompasses a complex system responsible for the coordinated contraction of the heart. In the developing heart, as well as in the adult heart, tissues of the (putative) CCS are characterized by different properties ...
M. R. M. Jongbloed, E. A. F. Mahtab, N. A. Blom, M. J. Schalij, A. C. Gittenberger-de Groot   +4 more
doaj   +1 more source

Evolution of the Sinus Venosus from Fish to Human

Journal of Cardiovascular Development and Disease, 2014
The sinus venosus, the cardiac chamber upstream of the (right) atrium, is a severely underinvestigated structure. Yet, its myocardium harbors the cardiac pacemaker in all vertebrates.
Bjarke Jensen, Bastiaan J. D. Boukens, Tobias Wang, Antoon F. M. Moorman, Vincent M. Christoffels   +4 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Granulomatosis with polyangiitis: a rare case of the coexistence of a critical lesion of the conduction system and the heart valve. Surprising echocardiogram [PDF]

, 2023
Barbara Brzezińska, Marta Skoczyńska, Katarzyna Gruszecka, Rafał Wyderka, Joanna Jaroch   +4 more
openalex   +1 more source

CaMKII-dependent regulation of cardiac Na(+) homeostasis. [PDF]

, 2014
Na(+) homeostasis is a key regulator of cardiac excitation and contraction. The cardiac voltage-gated Na(+) channel, NaV1.5, critically controls cell excitability, and altered channel gating has been implicated in both inherited and acquired arrhythmias.
Grandi, Eleonora, Herren, Anthony W
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Conduction System Pacing in Children and Congenital Heart Disease

Arrhythmia & Electrophysiology Review
Permanent cardiac pacing in children with congenital complete atrioventricular block (CCAVB) and/or congenital heart disease (CHD) is challenging.
Óscar Cano, Jeremy P Moore
doaj   +1 more source