Results 51 to 60 of about 2,706,025 (352)

Impact of an interatrial shunt device on survival and heart failure hospitalization in patients with preserved ejection fraction [PDF]

, 2019
Aims: Impaired left ventricular diastolic function leading to elevated left atrial pressures, particularly during exertion, is a key driver of symptoms and outcomes in heart failure with preserved ejection fraction (HFpEF). Insertion of an interatrial
Aytug, H, Bergmann, MW, Doughty, RN, Gustafsson, F, Hasenfuβ, G, Hausleiter, J, Hayward, C, Jondeau, G, Kaye, DM, Kolodziej, A, Lang, I, Malek, F, McKenzie, S, Penicka, M, Petrie, MC, Ponikowski, P, Post, M, Raake, P, REDUCE LAP-HF study investigators,, Rosenberg, M, Spelman, T, Trochu, J-N, Westenfeld, R   +22 more
core   +2 more sources

Weight Loss in Obese Patients With Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundIn heart failure (HF), weight loss (WL) has been associated with an adverse prognosis whereas obesity has been linked to lower mortality (the obesity paradox). The impact of WL in obese patients with HF is incompletely understood. Our objective
Elisabet Zamora, Carles Díez‐López, Josep Lupón, Marta de Antonio, Mar Domingo, Javier Santesmases, María Isabel Troya, Crisanto Díez‐Quevedo, Salvador Altimir, Antoni Bayes‐Genis   +9 more
doaj   +1 more source

Bone in heart failure [PDF]

Journal of Cachexia, Sarcopenia and Muscle, 2020
AbstractThere is an increasing interest in osteoporosis and reduced bone mineral density affecting not only post‐menopausal women but also men, particularly with coexisting chronic diseases. Bone status in patients with stable chronic heart failure (HF) has been rarely studied so far.
Goran Loncar, Goran Loncar, Goran Loncar, Natasa Cvetinovic, Stephan von Haehling, Andjelka M. Isakovic, Mitja Lainscak   +6 more
openaire   +5 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Design and Rationale of the Cognitive Intervention to Improve Memory in Heart Failure Patients Study [PDF]

, 2018
BACKGROUND: Memory loss is an independent predictor of mortality among heart failure patients. Twenty-three percent to 50% of heart failure patients have comorbid memory loss, but few interventions are available to treat the memory loss.
Dorsey, Susan G., Gao, Sujuan, Giordani, Bruno, Gradus-Pizlo, Irmina, Jung, Miyeon, Pressler, Susan J., Smith, Dean, Titler, Marita   +7 more
core   +2 more sources

Exercise intolerance and fatigue in chronic heart failure: is there a role for group III/IV afferent feedback? [PDF]

, 2020
Exercise intolerance and early fatiguability are hallmark symptoms of chronic heart failure. While the malfunction of the heart is certainly the leading cause of chronic heart failure, the patho-physiological mechanisms of exercise intolerance in these ...
Angius, Luca, Crisafulli, Antonio
core   +2 more sources

A new approach to characterize cardiac sodium storage by combining fluorescence photometry and magnetic resonance imaging in small animal research

Scientific Reports
Cardiac myocyte sodium (Na+) homoeostasis is pivotal in cardiac diseases and heart failure. Intracellular Na+ ([Na+]i) is an important regulator of excitation–contraction coupling and mitochondrial energetics.
Martin Christa, Franziska Dithmar, Tobias Weinaus, Michael Kohlhaas, Anahi-Paula Arias-Loza, Michelle Hofmann, Ibrahim A. Elabyad, Fabian T. Gutjahr, Christoph Maack, Wolfgang R. Bauer   +9 more
doaj   +1 more source

Association between the Length of Hospital Stay and 30-Day Outcomes in Patients Admitted with Acute Decompensated Heart Failure

Emergency Medicine International, 2023
Background and Aim. Regarding patients admitted with acute decompensated heart failure (ADHF), there are inconsistent reports surrounding the association between length of stay (LOS) and mortality or rehospitalization following discharge.
Melika Namvar, Mohammad Fakhrolmobasheri, Sadegh Mazaheri-Tehrani, Maryam Heidarpour, Maryam Emamimeybodi, Davood Shafie   +5 more
doaj   +1 more source

Cell Therapy in Heart Failure with Preserved Ejection Fraction

Cardiac Failure Review, 2022
Heart failure with preserved ejection fraction (HFpEF) is the most common cause of hospitalisation for heart failure. However, only limited effective treatments are available. Recent evidence suggests that HFpEF may result from a systemic proinflammatory
Sabina Frljak, Gregor Poglajen, Bojan Vrtovec   +2 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source