Results 61 to 70 of about 2,693,459 (310)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Acute Heart Failure as a First Manifestation of Primary Adrenal Insufficiency: Highly Lethal If Not Diagnosed!

Case Reports in Endocrinology
Background. Primary adrenal insufficiency is an uncommon condition that manifests as nonspecific symptoms such as fatigue, weight loss, salt craving, and hyperpigmentation.
Maryam Heidarpour, Mohammad Mehdi Zare, Shiva Armani, Hedie Torkashvan, Sadegh Mazaheri-Tehrani, Davood Shafie   +5 more
doaj   +1 more source

Performance Evaluation of a Preclinical SPECT Scanner with a Collimator Designed for Medium-Sized Animals

Molecular Imaging, 2022
Background. Equipped with two stationary detectors, a large bore collimator for medium-sized animals has been recently introduced for dedicated preclinical single-photon emission computed tomography (SPECT) imaging.
Yohji Matsusaka, Rudolf A. Werner, Paula Arias-Loza, Naoko Nose, Takanori Sasaki, Xinyu Chen, Constantin Lapa, Takahiro Higuchi   +7 more
doaj   +1 more source

Deletion of low molecular weight protein tyrosine phosphatase (Acp1) protects against stress-induced cardiomyopathy. [PDF]

, 2015
The low molecular weight protein tyrosine phosphatase (LMPTP), encoded by the ACP1 gene, is a ubiquitously expressed phosphatase whose in vivo function in the heart and in cardiac diseases remains unknown.
Al-Habeeb, Waleed, Al-Haffar, Kamar Mohamed Adib, Al-Mohanna, Falah, Alvarez, Roberto, Assiri, Abdullah, Awad, Salma Mahmoud, Belhaj, Karim, Bottini, Nunzio, Colak, Dilek, Jordan, Maria C, Kunhi, Muhammad, Liu, Yingge, Marashly, Qussay, Poizat, Coralie, Quijada, Pearl, Roos, Kenneth P, Stanford, Stephanie M, Sussman, Mark, Toko, Haruhiro, Wade, Fallou, Zahid, Israa   +20 more
core   +2 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Insuficiencia cardíaca descompensada en un solo centro de un país latinoamericano: hallazgos de los primeros 1595 casos en el registro ICARUS

Archivos de Cardiología de México
Objetivo: Describir los aspectos metodológicos, las características sociodemográficas y clínicas de los pacientes hospitalizados con ICAD y sus desenlaces a corto plazo.
Lyda Z. Rojas, Sergio A. Gómez-Ochoa, Jaime A. Rodríguez, Karen A. García-Rueda, Angela M. Torres-Bustamante, Daniel R. Botero, María Cantillo-Reines, Angie Y. Serrano-García, Adriana M. Jurado, Kelly J. Castro, Katerine Pinilla, Angie C. Mendoza-Quiñonez, Nelly J. Vasquez, Yeinmy Y. Alvarez, Maribel Rojas, Diana M. Ortega-Solano, Yesenia Sanabria, Angelica Vargas-Sanabria, Aura M. Cáceres, Paula S. Bohorquez-Hernández, Carlos Portillo, Luis E. Echeverria   +21 more
doaj   +1 more source

Improving Heart Failure Education Prior to Discharge: An Emmi Implementation Project [PDF]

, 2017
Background: Heart failure is one of the leading causes of hospitalizations and increased health care costs in the United States. Many patients are readmitted within 30 days of discharge, resulting in increased costs.
McCord, Elizabeth
core   +2 more sources

Heart Failure Anticoagulation Teach-Back Education and Readmissions [PDF]

, 2020
: Heart failure affects millions of Americans each year. Treatment of advanced heart failure with reduced ejection fraction and left ventricular failure is sometimes treated with implantation of a left-ventricular assist device.

core  

Monitoring functional capacity in heart failure. [PDF]

, 2019
This document reflects the key points of a consensus meeting of the Heart Failure Association of European Society of Cardiology (ESC) held to provide an overview the role of physiological monitoring in the complex multimorbid heart failure (HF) patient ...
Aaby, Agostoni, Antunes-Correa, Baeza-Trinidad, Bona, Chrysohoou, Compostella, Cornelis, Corra’, Crisafulli, Crisafulli, Cugusi, Emami, Fernandes-Silva, Fernberg, Giannoni, Giuseppe Rosano, Graziani, Griffo, Guazzi, Guazzi, Guazzi, Haapala, Huang, Ilaria Spoletini, Iliou, Kadoglou, Kamiya, Kato, Kirkman, Kleber, Kokkinos, Lachman, Laukkanen, Lavie, Lindgren, Mandigout, Mandini, Mantegazza, Marcos-Forniol, Massimo F Piepoli, Meijers, Montero, Montero, Palau, Panagopoulou, Panagopoulou, Sabbag, Saeidifard, Sato, Schnohr, Van Iterson, Vanhees, Vasankari, Ventura, Ware, Wolsk, Zafrir, Zhao   +58 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source