Results 51 to 60 of about 4,030,165 (305)

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

Sarcopenia and Heart Failure [PDF]

Nutrients, 2020
Modifications of lean mass are a frequent critical determinant in the pathophysiology and progression of heart failure (HF). Sarcopenia may be considered one of the most important causes of low physical performance and reduced cardiorespiratory fitness in older patients with HF. Sarcopenia is frequently misdiagnosed as cachexia. However, muscle wasting
Curcio F., Testa G., Liguori I., Papillo M., Flocco V., Panicara V., Galizia G., Della-Morte D., Gargiulo G., Cacciatore F., Bonaduce D., Landi F., Abete P.   +12 more
openaire   +4 more sources

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Heart Failure

JACC: Heart Failure, 2013
Despite major improvements in the treatment of virtually all cardiac disorders, heart failure (HF) is an exception, in that its prevalence is rising, and only small prolongations in survival are occurring. An increasing fraction, especially older women with diabetes, obesity, and atrial fibrillation exhibit HF with preserved systolic function.
openaire   +2 more sources

Epidemiology of Heart Failure [PDF]

European Journal of Heart Failure, 2020
Abstract The heart failure syndrome has first been described as an emerging epidemic about 25 years ago. Today, because of a growing and ageing population, the total number of heart failure patients still continues to rise. However, the case mix of heart failure seems to be evolving. Incidence has stabilized and may even be decreasing
Groenewegen, Amy, Rutten, Frans H., Mosterd, Arend, Hoes, Arno W.   +3 more
openaire   +2 more sources

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Prevalence and significance of alterations in cardiac structure and function in patients with heart failure and a preserved ejection fraction [PDF]

, 2011
<p><b>Background:</b> The purpose of this study was to examine the prevalence of abnormalities in cardiac structure and function present in patients with heart failure and a preserved ejection fraction (HFPEF) and to determine whether ...
Michel Komajda, Baicu, C.F., John S. Gottdiener, Massie, B.M., Zile, M.R., Robert McKelvie, Scott J. Hetzel, Michael R. Zile, John J. McMurray, Catalin F. Baicu, McMurray, J.J., Barry M. Massie, McKelvie, R., Gottdiener, J.S., Hetzel, S.J., Komajda, M., McMurray, J.J.V., Carson, P.E., Peter E. Carson   +18 more
core   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Developing new treatments for heart failure: focus on the heart [PDF]

, 2016
Compared with heart failure (HF) care 20 to 30 years ago, there has been tremendous advancement in therapy for ambulatory HF with reduced ejection fraction with the use of agents that block maladaptive neurohormonal pathways.
Colucci, Wilson S., Epstein, Stephen E., Sabbah, Hani N., Gheorghiade, Mihai, Epstein, Stephen E, Wahlander, Karin, Crandall, David, Sikora, Sergey, Larson, Christopher J, Okada, Shunichiro, Parsey, Ramin V, Dunnmon, Preston, Colucci, Wilson S, Shah, Sanjiv J, Sabbah, Hani N, Deckelbaum, Lawrence I., Butler, Javed, Senni, Michele, Greene, Stephen J, Shah, Sanjiv J., Greene, Stephen J., Parsey, Ramin V., Carr, James, Cleland, John GF, Kramer, Frank, Cleland, John G.F., Dinh, Wilfried, Deckelbaum, Lawrence I, Krahn, Thomas, Kim, Raymond J., Kim, Raymond J, Larson, Christopher J., Stockbridge, Norman, Dunnmon, P, Epstein, SE, Sikora, S, Okada, S, Carr, J, Kramer, F, Crandall, D, Sabbah, HN, Larson, CJ, Stockbridge, N, Gheorghiade, M, Cleland, JG, Senni, M, Butler, J, Krahn, T, Deckelbaum, LI, Parsey, RV, Wahlander, K, Kim, RJ, Greene, SJ, Colucci, WS, Dinh, W, Shah, SJ   +55 more
core   +3 more sources

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source