Results 51 to 60 of about 2,693,459 (310)

Biomarkers Beyond the Natriuretic Peptides for Chronic Heart Failure: Galectin-3 and Soluble ST2. [PDF]

, 2012
B-type natriuretic peptide (BNP) and NT-proBNP are widely used plasma biomarkers for the diagnosis of acute decompensated heart failure and prognosis for future cardiac disease.
Wu, Alan HB
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Multiparity induces persistent myocardial structural, functional and transcriptomic remodelling in mice

Scientific Reports
Pregnancy poses unique hemodynamic and metabolic demands on the heart. Recent data suggests that a history of multiple pregnancies may be associated with a late-term increased risk of heart failure with preserved ejection fraction (HFpEF), however, the ...
Ruth R. Magaye, Bing H. Wang, Hongyi R. Liu, Shanae Bailey, Rithy Nuon, Sabrina Sutano, Michael Nyugen, Helen Kiriazis, Kyah Grigolon, Luchen Shan, William W. H. Ho, Fumihiko Takeuchi, Daniel G. Donner, David M. Kaye   +13 more
doaj   +1 more source

Association between the Length of Hospital Stay and 30-Day Outcomes in Patients Admitted with Acute Decompensated Heart Failure

Emergency Medicine International, 2023
Background and Aim. Regarding patients admitted with acute decompensated heart failure (ADHF), there are inconsistent reports surrounding the association between length of stay (LOS) and mortality or rehospitalization following discharge.
Melika Namvar, Mohammad Fakhrolmobasheri, Sadegh Mazaheri-Tehrani, Maryam Heidarpour, Maryam Emamimeybodi, Davood Shafie   +5 more
doaj   +1 more source

Eigenhearts for diagnosis of congestive heart failure (CHF) [PDF]

, 2006
Common cardiac diseases such as cardio-myopathy, coronary artery diseases, and valve diseases, result in abnormal myocardial movement, which could eventually lead to heart failure, also called congestive heart failure (CHF). CHF is a disease in which the
Ahanathapillai, Vijayalakshmi, Hamilton, David   +1 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Single Center Experience With Impella 5.5 for Escalation and De-Escalation of Cardiogenic Shock Patients

Journal of Interventional Cardiology
Temporary mechanical circulatory support (tMCS) devices are a critical component for treating patients with cardiogenic shock (CS). We analyzed use of Impella 5.5 device for efficacy and safety in a single-center CS population from February 2022 and ...
Ioana Dumitru, Debbie Rinde-Hoffman, Maria Sevillano, Leeandra Schnell, Elizabeth Quintilliani, Swaroop Bommareddi   +5 more
doaj   +1 more source

Weight Loss in Obese Patients With Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundIn heart failure (HF), weight loss (WL) has been associated with an adverse prognosis whereas obesity has been linked to lower mortality (the obesity paradox). The impact of WL in obese patients with HF is incompletely understood. Our objective
Elisabet Zamora, Carles Díez‐López, Josep Lupón, Marta de Antonio, Mar Domingo, Javier Santesmases, María Isabel Troya, Crisanto Díez‐Quevedo, Salvador Altimir, Antoni Bayes‐Genis   +9 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Risk related to pre–diabetes mellitus and diabetes mellitus in heart failure with reduced ejection fraction: insights from prospective comparison of ARNI with ACEI to determine impact on global mortality and morbidity in heart failure trial [PDF]

, 2016
Background—The prevalence of pre–diabetes mellitus and its consequences in patients with heart failure and reduced ejection fraction are not known.
Cardoso, José Silva, Desai, Akshay S., Jhund, Pardeep S., Kristensen, Søren L., Lefkowitz, Martin P., Martinez, Felipe, McMurray, John J.V., Merkely, Bela, Packer, Milton, Preiss, David, Rizkala, Adel R., Rouleau, Jean L., Shi, Victor C., Solomon, Scott D., Squire, Iain, Starling, Randall C., Swedberg, Karl, Zile, Michael R.   +17 more
core   +1 more source