Results 121 to 130 of about 163,785 (367)

Contemporary management of heart failure in the elderly [PDF]

, 2019
The foundation of the treatment of heart failure with reduced ejection fraction is a number of pharmacotherapies shown to reduce morbidity and mortality in large randomised multinational clinical trials.
Jhund, Pardeep S., Osmanska, Joanna
core   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

The value of exercise echocardiography in heart failure with preserved ejection fraction

Journal of Ultrasonography, 2019
Diastolic stress test is something that is now acknowledged in the recommendations and guidelines for diagnosing heart failure with preserved ejection fraction.
Erwan Donal
doaj   +1 more source

Clonal Hematopoiesis and Incident Heart Failure With Preserved Ejection Fraction

JAMA Network Open
Key Points Question Are clonal hematopoiesis of indeterminate potential (CHIP) or certain CHIP driver genes associated with a specific heart failure (HF) subtype?
A. Schuermans, M. Honigberg, L. Raffield, Bing Yu, Mary B Roberts, C. Kooperberg, Pinkal M. Desai, April P. Carson, Amil M. Shah, C. Ballantyne, A. Bick, Pradeep Natarajan, J. Manson, E. Whitsel, Charles B. Eaton, Alex P. Reiner   +15 more
semanticscholar   +1 more source

Heart Failure With Preserved Ejection Fraction In Perspective.

Circulation Research, 2019
Approximately half of the patients with signs and symptoms of heart failure have a left ventricular ejection fraction that is not markedly abnormal. Despite the historically initial surprise, heightened risks for heart failure specific major adverse ...
M. Pfeffer, A. Shah, B. Borlaug
semanticscholar   +1 more source

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Advanced Science, EarlyView.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source

Air pollution and heart failure: relationship with the ejection fraction [PDF]

, 2013
To study whether the concentrations of particulate matter in ambient air are associated with hospital admission due to heart failure in patients with heart failure with preserved ejection fraction and reduced ejection ...
Abreu Afonso, Javier, Abreu González, Pedro, Arroyo Ucar, Eduardo, Avanzas, Pablo, Domínguez Rodríguez, Alberto, González Ramos, Yenny, Rodríguez González, Sergio, Suárez Prera, Rubén A.   +7 more
core   +1 more source

Autonomous Machine Learning‐Based Classification and Arrangement of Submillimeter Objects Using a Capillary Force Gripper

Advanced Intelligent Discovery, EarlyView.
This study presents an automated system integrating a capillary force gripper and machine learning‐based object detection for sorting and placing submillimeter objects. The system achieved stable and simultaneous manipulation of four object types, with an average task time of 86.0 seconds and a positioning error of 157 ± 84 µm, highlighting its ...
Satoshi Ando, Naoto Watanabe, Chihiro Sekine, Shogen Sekiguchi, Ohmi Fuchiwaki   +4 more
wiley   +1 more source

Prognostic Value of Anxiety Between Heart Failure With Reduced Ejection Fraction and Heart Failure With Preserved Ejection Fraction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Evidence suggests differences in clinical characteristics, causes, and prognoses between heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF).
Tin‐Kwang Lin, Bo‐Cheng Hsu, Yi‐Da Li, Chi‐Hsien Chen, Jiunn‐Wen Lin, Chen‐Yu Chien, Chia‐Ying Weng   +6 more
doaj   +1 more source

Advances in 3D Printing Technologies for Fabricating Magnetic Soft Microrobots

Advanced Intelligent Systems, EarlyView.
This paper gives an in‐depth synopsis of various additive manufacturing technologies used to fabricate magnetic soft microrobots. The review covers the basics behind magnetism and the materials used. It then dives into three‐dimensional printing technologies including extrusion, photopolymerization, jetting, etc.
Kaitlyn Clancy, Siwen Xie, Onaizah Onaizah   +2 more
wiley   +1 more source