Results 21 to 30 of about 264,442 (390)

Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction.

New England Journal of Medicine, 2022
BACKGROUND Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure and cardiovascular death among patients with chronic heart failure and a left ventricular ejection fraction of 40% or less.
S. Solomon, J. McMurray, B. Claggett, R. D. de Boer, D. DeMets, Adrian F. Hernandez, S. Inzucchi, M. Kosiborod, C. Lam, F. Martinez, Sanjiv J. Shah, Akshay S. Desai, P. Jhund, J. Bělohlávek, C. Chiang, C. Borleffs, J. Comín-Colet, D. Dobreanu, J. Drożdż, J. Fang, M. Alcocer-Gamba, Waleed Al habeeb, Yaling Han, Jose Walter Cabrera Honorio, S. Janssens, T. Katova, M. Kitakaze, B. Merkely, E. O’Meara, J. Saraiva, S. Tereshchenko, J. Thierer, M. Vaduganathan, O. Vardeny, S. Verma, V. Pham, U. Wilderäng, Natalia Zaozerska, E. Bachus, D. Lindholm, Magnus Petersson, A. Langkilde   +41 more
semanticscholar   +1 more source

Discriminative Value of Serum Irisin in Prediction of Heart Failure with Different Phenotypes among Patients with Type 2 Diabetes Mellitus

Cells, 2022
Recent studies have shown that circulating levels of irisin are prognostic factors in heart failure (HF), but no data are available on the predictive role of irisin in patients with type 2 diabetes mellitus (T2DM) and different phenotypes of HF.
Alexander A. Berezin, Michael Lichtenauer, Elke Boxhammer, Eric Stöhr, Alexander E. Berezin   +4 more
doaj   +1 more source

Sirt1 Activity in PBMCs as a Biomarker of Different Heart Failure Phenotypes

Biomolecules, 2020
Heart Failure (HF) is a syndrome, which implies the existence of different phenotypes. The new categorization includes patients with preserved ejection fraction (HFpEF), mid-range EF (HFmrEF), and reduced EF (HFrEF) but the molecular mechanisms involved ...
Valeria Conti, Graziamaria Corbi, Maria Vincenza Polito, Michele Ciccarelli, Valentina Manzo, Martina Torsiello, Emanuela De Bellis, Federica D’Auria, Gennaro Vitulano, Federico Piscione, Albino Carrizzo, Paola Di Pietro, Carmine Vecchione, Nicola Ferrara, Amelia Filippelli   +14 more
doaj   +1 more source

Therapeutic Stalemate in Heart Failure With Preserved Ejection Fraction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
The findings of randomized trials of neurohormonal modulation have been neutral in heart failure with preserved ejection fraction and consistently positive in heart failure with reduced ejection.
Rohan Samson, Thierry H. Le Jemtel
doaj   +1 more source

Evidence-Based Medical Therapy in Patients With Heart Failure With Reduced Ejection Fraction and Chronic Kidney Disease

Circulation, 2022
Chronic kidney disease (CKD) as identified by a reduced estimated glomerular filtration rate (eGFR) is a common comorbidity in patients with heart failure with reduced ejection fraction (HFrEF).
I. Beldhuis, C. Lam, J. Testani, A. Voors, H. V. Van Spall, J. T. ter Maaten, K. Damman   +6 more
semanticscholar   +1 more source

Heart failure with mid‐range ejection fraction: pro and cons of the new classification of Heart Failure by European Society of Cardiology guidelines

ESC Heart Failure, 2020
Currently, the assessment of left ventricular ejection fraction (LVEF) is the cornerstone of the classification of patients with heart failure (HF). The mid‐range LVEF (HFmrEF) category was identified in an attempt to uncover specific characteristics of ...
Luca Branca, Marco Sbolli, Marco Metra, Marat Fudim   +3 more
doaj   +1 more source

Effectiveness and safety of transcatheter aortic valve replacement in elderly people with severe aortic stenosis with different types of heart failure

BMC Cardiovascular Disorders, 2023
Background Impaired left ventricular function is an independent predictor of adverse clinical outcomes in patients with aortic stenosis. The aim of this study is to evaluate the short-term changes of echocardiographic parameters, New York Heart ...
Mei Dong, Lizhen Wang, Gary Tse, Tao Dai, Lihong Wang, Zhicheng Xiao, Tong Liu, Faxin Ren   +7 more
doaj   +1 more source

Nonalcoholic Fatty Liver Disease and Risk of Heart Failure Among Medicare Beneficiaries

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Nonalcoholic fatty liver disease (NAFLD) and heart failure (HF) are increasing in prevalence. The independent association between NAFLD and downstream risk of HF and HF subtypes (HF with preserved ejection fraction and HF with reduced ejection
Marat Fudim, Lin Zhong, Kershaw V. Patel, Rohan Khera, Manal F. Abdelmalek, Anna Mae Diehl, Robert W. McGarrah, Jeroen Molinger, Cynthia A. Moylan, Vishal N. Rao, Kara Wegermann, Ian J. Neeland, Ethan A. Halm, Sandeep R. Das, Ambarish Pandey   +14 more
doaj   +1 more source

2021 Update to the 2017 ACC Expert Consensus Decision Pathway for Optimization of Heart Failure Treatment: Answers to 10 Pivotal Issues About Heart Failure With Reduced Ejection Fraction

KIDNEYS, 2021
No ...
No Authors
semanticscholar   +1 more source

Immunity, Inflammation and Heart Failure: Their Role on Cardiac Function and Iron Status [PDF]

, 2019
Aims: Heart failure is a clinical syndrome characterized by subclinical systemic inflammation and immune system activation associated with iron deficiency.
Corrao S., Gigliotti S., Greco M., Hribal M. L., Miceli S., Perticone F., Perticone M., Pinto A., Sesti G., Suraci E., Zito R.   +10 more
core   +1 more source