Results 51 to 60 of about 264,442 (390)

Comparison of New York Heart Association Class and Patient-Reported Outcomes for Heart Failure With Reduced Ejection Fraction.

JAMA cardiology, 2021
Importance It is unclear how New York Heart Association (NYHA) functional class compares with patient-reported outcomes among patients with heart failure (HF) in contemporary US clinical practice.
S. Greene, J. Butler, J. Spertus, A. Hellkamp, M. Vaduganathan, A. DeVore, N. Albert, Carol I. Duffy, J. Patterson, L. Thomas, Fredonia B. Williams, Adrian F. Hernandez, G. Fonarow   +12 more
semanticscholar   +1 more source

Association of Change in N-Terminal Pro-B-Type Natriuretic Peptide Following Initiation of Sacubitril-Valsartan Treatment With Cardiac Structure and Function in Patients With Heart Failure With Reduced Ejection Fraction.

Journal of the American Medical Association (JAMA), 2019
Importance In patients with heart failure and reduced ejection fraction (HFrEF), treatment with sacubitril-valsartan reduces N-terminal pro-b-type natriuretic peptide (NT-proBNP) concentrations. The effect of sacubitril-valsartan on cardiac remodeling is
MD JamesL.JanuzziJr, PhD MargaretF.Prescott, Mdmphmba JavedButler, Mdmhs G.MichaelFelker, MD AlanS.Maisel, KevinMcCague, PhD AlexanderCamacho, Mdmph IleanaL.Piña, MD RicardoA.Rocha, Mdmph AmilM.Shah, PharmD KristinM.Williamson, MD ScottD.Solomon, PrescottButler Felker Januzzi, Pina Maisel, S. Rocha, McCague, Camacho, Camacho McCague, CamachoRocha Williamson Butler, ButlerFelker Prescott, Rocha Maisel, Solomon Williamson   +21 more
semanticscholar   +1 more source

Sacubitril/valsartan in patients with mildly reduced or preserved ejection fraction and worsening heart failure: A review

Терапевтический архив, 2023
Heart failure with mildly reduced ejection fraction and heart failure with preserved ejection fraction are associated with significant morbidity and mortality, as well as growing economic burden.
Igor V. Zhirov, Natalia V. Safronova, Sergey N. Tereshchenko   +2 more
doaj   +1 more source

Expression of epicardial adipose tissue thermogenic genes in patients with reduced and preserved ejection fraction heart failure [PDF]

, 2017
[Abstract] Epicardial adipose tissue has been proposed to participate in the pathogenesis of heart failure. The aim of our study was to assess the expression of thermogenic genes (Uncoupling protein 1 (UCP1), peroxisome proliferator-activated receptor ...
Carrasco-Chinchilla, Fernando, Crespo-Leiro, María Generosa, García-Pinilla, José Manuel, Garrido-Sánchez, Lourdes, Gómez Doblas, Juan José, Jiménez-Navarro, Manuel, Morcillo-Hidalgo, Luis, Moreno-Santos, Inmaculada, Pérez-Belmonte, Luis M., Santiago-Fernández, Concepción, Sánchez-Fernández, Pedro L., Teresa Galván, Eduardo de   +11 more
core   +5 more sources

Ribose supplementation alone or with elevated creatine does not preserve high energy nucleotides or cardiac function in the failing mouse heart [PDF]

, 2013
Background: Reduced levels of creatine and total adenine nucleotides (sum of ATP, ADP and AMP) are hallmarks of chronic heart failure and restoring these pools is predicted to be beneficial by maintaining the diseased heart in a more favourable energy ...
Aksentijevic, Dunja, Faller, Kiterie M.E., Lygate, Craig A., Medway, Debra J., Neubauer, Stefan, Schneider, Jürgen E., Sebag-Montefiore, Liam   +6 more
core   +8 more sources

Axial Muscle Size as a Strong Predictor of Death in Subjects With and Without Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background The impact of skeletal muscle size, quantified using simple noninvasive images routinely obtained during cardiac magnetic resonance imaging studies on mortality in the heart failure (HF) population is currently unknown.
Anupam Kumar, Bilal A. Ansari, Jessica Kim, Arpita Suri, Sowmya Gaddam, Sowjanya Yenigalla, Jagan M. Vanjarapu, Senthil Selvaraj, Dheera Tamvada, Jonathan Lee, Scott R. Akers, Julio A. Chirinos   +11 more
doaj   +1 more source

Cardiac metabolism — A promising therapeutic target for heart failure [PDF]

, 2017
Both heart failure with reduced ejection fraction (HFrEF) and with preserved ejection fraction (HFpEF) are associated with high morbidity and mortality.
Frenneaux, Michael P, Loudon, Brodie L, Madhani, Melanie, Noordali, Hannah   +3 more
core   +2 more sources

Predicting Heart Failure With Preserved and Reduced Ejection Fraction [PDF]

Circulation: Heart Failure, 2016
Background— Heart failure (HF) is a prevalent and deadly disease, and preventive strategies focused on at-risk individuals are needed. Current HF prediction models have not examined HF subtypes. We sought to develop and validate risk prediction models for HF with preserved and reduced ejection fraction (HFpEF, HFrEF).
Ho, Jennifer E., Enserro, Danielle, Brouwers, Frank P., Kizer, Jorge R., Shah, Sanjiv J., Psaty, Bruce M., Bartz, Traci M., Santhanakrishnan, Rajalakshmi, Lee, Douglas S., Chan, Cheeling, Liu, Kiang, Blaha, Michael J., Hillege, Hans L., van der Harst, Pim, van Gilst, Wiek H., Kop, Willem J., Gansevoort, Ron T., Vasan, Ramachandran S., Gardin, Julius M., Levy, Daniel, Gottdiener, John S., de Boer, Rudolf A., Larson, Martin G.   +22 more
openaire   +3 more sources

Spironolactone for heart failure with preserved ejection fraction [PDF]

, 2014
BACKGROUND: Mineralocorticoid-receptor antagonists improve the prognosis for patients with heart failure and a reduced left ventricular ejection fraction.
Anand, Inder S., Assmann, Susan F., Boineau, Robin, Claggett, Brian, Clausell, Nadine, Desai, Akshay S., Diaz, Rafael, Fleg, Jerome L., Gordeev, Ivan, Harty, Brian, Heitner, John F., Kenwood, Christopher T., Lewis, Eldrin F., McKinlay, Sonja M., O'Meara, Eileen, Pfeffer, Marc A., Pitt, Bertram, Probstfield, Jeffrey L., Shaburishvili, Tamaz, Shah, Sanjiv J., Solomon, Scott D., Sweitzer, Nancy K., TOPCAT Investigators, Ventura, H., Yang, Song   +24 more
core   +1 more source

Genetic Risk and Atrial Fibrillation in Patients with Heart Failure [PDF]

, 2020
Aims: To study the association between an atrial fibrillation (AF) genetic risk score with prevalent AF and all-cause mortality in patients with heart failure.
Anker, Stefan D., Artola, Vicente A., Benjamin, Emelia J., Dickstein, Kenneth, Filippatos, Gerasimos S., Kloosterman, Mariëlle, Koekemoer, Andrea, Lam, Carolyn S. P., Lang, Chim, Meer, Peter van der, Metra, Marco, Nelson, Christopher P., Ng, Leong L., Ponikowski, Piotr, Rienstra, Michiel, Romaine, Simon P. R., Roselli, Carolina, Samani, Nilesh J., Santema, Bernadet T., van der Harst, Pim, Van Gelder, Isabelle C., Van Veldhuisen, Dirk Jan, Voors, Adriaan A.   +22 more
core   +3 more sources