Results 81 to 90 of about 112,374 (313)
Comparison of Clinical Features and Outcomes of Patients Hospitalized With Heart Failure and Normal Ejection Fraction (≥55%) Versus Those With Mildly Reduced (40% to 55%) and Moderately to Severely Reduced (<40%) Fractions [PDF]
, 2008 Nancy K. Sweitzer +4 more
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Advanced Science, EarlyView.FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song +17 more
wiley +1 more source
International Journal of General Medicine, 2022 Zhengyang Hao, Yanzhou Zhang Department of Cardiology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People’s Republic of ChinaCorrespondence: Yanzhou Zhang, Department of Cardiology, the First Affiliated Hospital of Zhengzhou
Hao Z, Zhang Y
doaj
Aldosterone blockade in patients with heart failure and a reduced left ventricular ejection fraction [PDF]
, 2008 Bertram Pitt
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Management of heart failure with reduced ejection fraction
Heart, 2022 Paul M Haydock, Andrew S Flett
openaire +2 more sources
Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi
Advanced Science, EarlyView.The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda +12 more
wiley +1 more source
Actigraphy in Heart Failure Subjects with a Reduced and Normal Ejection Fraction [PDF]
, 2008 Jason Howell +6 more
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PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity
Advanced Science, EarlyView.Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley +1 more source
Рациональная фармакотерапия в кардиологииHeart failure with reduced ejection fraction (HFrEF) is a public health issue, because some patients, despite using standard treatment, still develop worsening heart failure.
I. V. Gribkova
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Advanced Intelligent Discovery, EarlyView.This study presents an automated system integrating a capillary force gripper and machine learning‐based object detection for sorting and placing submillimeter objects. The system achieved stable and simultaneous manipulation of four object types, with an average task time of 86.0 seconds and a positioning error of 157 ± 84 µm, highlighting its ...
Satoshi Ando +4 more
wiley +1 more source