Results 81 to 90 of about 2,227,737 (406)

Vericiguat and NT‐proBNP in patients with heart failure with reduced ejection fraction: analyses from the VICTORIA trial

ESC Heart Failure, 2022
Aims Treatment response to vericiguat, based on baseline N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) subgroups specified in the protocol, was evaluated in the heart failure (HF) VICTORIA trial population by post hoc analysis of combined lower ...
Michele Senni, Jose Lopez‐Sendon, Alain Cohen‐Solal, Piotr Ponikowski, Richard Nkulikiyinka, Cecilia Freitas, Vanja Miodrag Vlajnic, Lothar Roessig, Burkert Pieske   +8 more
doaj   +1 more source

Understanding Heart-Failure Patients EHR Clinical Features via SHAP Interpretation of Tree-Based Machine Learning Model Predictions [PDF]

arXiv, 2021
Heart failure (HF) is a major cause of mortality. Accurately monitoring HF progress and adjust therapies are critical for improving patient outcomes. An experienced cardiologist can make accurate HF stage diagnoses based on combination of symptoms, signs, and lab results from the electronic health records (EHR) of a patient, without directly measuring ...
arxiv  

Cost-effectiveness of Dapagliflozin for Treatment of Patients With Heart Failure With Reduced Ejection Fraction.

JAMA cardiology, 2021
Importance In the Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure (DAPA-HF) trial, dapagliflozin was shown to reduce cardiovascular mortality and hospitalizations due to heart failure while improving patient-reported health status ...
J. Parizo, J. Goldhaber-Fiebert, J. Salomon, K. Khush, J. Spertus, P. Heidenreich, Alexander T. Sandhu   +6 more
semanticscholar   +1 more source

Heart failure with preserved ejection fraction. [PDF]

, 2012
Heart failure with preserved ejection fraction (HFpEF) has recently emerged as a major cause of cardiovascular morbidity and mortality. Contrary to initial beliefs, HFpEF is now known to be as common as heart failure with reduced ejection fraction (HFrEF)
ElGuindy, A, Yacoub, MH
core   +1 more source

Magnesium, Oxidative Stress, Inflammation, and Cardiovascular Disease

Antioxidants, 2020
Hypomagnesemia is commonly observed in heart failure, diabetes mellitus, hypertension, and cardiovascular diseases. Low serum magnesium (Mg) is a predictor for cardiovascular and all-cause mortality and treating Mg deficiency may help prevent ...
Man Liu, Samuel C. Dudley
doaj   +1 more source

Reduced Lymphatic Reserve in Heart Failure With Preserved Ejection Fraction [PDF]

Journal of the American College of Cardiology, 2020
Microvascular dysfunction plays an important role in the pathogenesis of heart failure with preserved ejection fraction (HFpEF). However, no mechanistic link between systemic microvasculature and congestion, a central feature of the syndrome, has yet been investigated.This study aimed to investigate capillary-interstitium fluid exchange in HFpEF ...
Giacomo Rossitto, Giacomo Rossitto, Christian Delles, Christine McAllister, Sheon Mary, John Paul Rocchiccioli, Mark C. Petrie, Ninian Nicholas Lang, Rhian M. Touyz, Clare Murphy, Karla B Neves, Laura Haddow   +11 more
openaire   +4 more sources

Effect of Empagliflozin on Left Ventricular Volumes in Patients With Type 2 Diabetes, or Prediabetes, and Heart Failure With Reduced Ejection Fraction (SUGAR-DM-HF)

Circulation, 2020
Supplemental Digital Content is available in the text.
Matthew M. Y. Lee, K. Brooksbank, K. Wetherall, K. Mangion, G. Roditi, R. Campbell, C. Berry, Victor Chong, Liz Coyle, K. Docherty, J. Dreisbach, Catherine Labinjoh, N. Lang, V. Lennie, A. McConnachie, C. Murphy, C. Petrie, J. Petrie, Iain A Speirits, S. Sourbron, P. Welsh, R. Woodward, A. Radjenovic, P. Mark, J. McMurray, P. Jhund, M. Petrie, N. Sattar   +27 more
semanticscholar   +1 more source

A Systematic Review and Meta-Analysis [PDF]

, 2020
BACKGROUND Medical therapy for heart failure with reduced ejection fraction evolved since trials validated the use of implantable cardioverter-defibrillators (ICDs). We sought to evaluate the performance of ICDs in reducing mortality in the era of modern
Adragão, Pedro, Carmo, João, Carmo, Pedro, Carvalho, Salomé, Cavaco, Diogo, Costa, Francisco Moscoso, Ferreira, Jorge, Gama, Francisco, Mendes, Miguel, Morgado, Francisco Belo   +9 more
core   +2 more sources

Distinct Network Morphologies from In Situ Polymerization of Microtubules in Giant Polymer‐Lipid Hybrid Vesicles

Advanced Biology, EarlyView.
The successful in situ polymerization of microtubules in giant polymer‐lipid hybrid vesicles is illustrated. The microtubules formed in the giant hybrid vesicles exhibit different morphologies including lumenal network formation and membrane association. Abstract Creating artificial cells with a dynamic cytoskeleton, akin to those in living cells, is a
Paula De Dios Andres, Mousumi Akter, Cecilie Ryberg, Brigitte Städler, Allen P. Liu   +4 more
wiley   +1 more source

SimLVSeg: Simplifying Left Ventricular Segmentation in 2D+Time Echocardiograms with Self- and Weakly-Supervised Learning [PDF]

arXiv, 2023
Echocardiography has become an indispensable clinical imaging modality for general heart health assessment. From calculating biomarkers such as ejection fraction to the probability of a patient's heart failure, accurate segmentation of the heart structures allows doctors to assess the heart's condition and devise treatments with greater precision and ...
arxiv