Results 211 to 220 of about 916,312 (327)

Single‐Virus Stochastic Biosensing: Proof of Concept for SARS‐CoV‐2 Detection in Complex Medium Using CMOS‐Based Nanocapacitor Arrays

Advanced Sensor Research, EarlyView.
SARS‐CoV‐2 particles in complex cell culture medium are detected using high‐frequency electrical measurements. This is made possible through the use of large arrays of independently addressable nanoelectrodes implemented using complementary metal oxide semiconductor (CMOS), semiconductor technology.
Suryasnata Tripathy, Mohammad Saghafi, Sudip Kumar Dutta, Stijn van der Ham, Diogenis Salvanos, Cecilia Laborde, Byron Martina, Serge G. Lemay   +7 more
wiley   +1 more source

Successful Treatment of Infective Endocarditis at 33 Weeks' Gestation Causing Acute Left Heart Failure. [PDF]

Clin Case Rep
Masaki M, Wakasa M, Kuzume Y, Sawaguchi J, Takamura TA, Fujibayashi K, Takano T, Kajinami K.   +7 more
europepmc   +1 more source

Cytokine mRNA Delivery and Local Immunomodulation in the Placenta Using Lipid Nanoparticles

Advanced Therapeutics, EarlyView.
This article evaluates lipid nanoparticles to deliver immunomodulatory mRNA to placental cells and mouse placentas to study and treat the immune underpinnings of placenta‐related diseases. Lipid nanoparticles induce cytokine secretion and macrophage polarization toward an anti‐inflammatory state.
Samuel I. Hofbauer, Luisa A. Fink, Rachel E. Young, Tara Vijayakumar, Katherine M. Nelson, Nia Bellopede, Mohamad‐Gabriel Alameh, Drew Weissman, Jason P. Gleghorn, Rachel S. Riley   +9 more
wiley   +1 more source

Surgical Management of Ankle Fracture in Late Pregnancy: A Case Report. [PDF]

Cureus
Kasai T, Ata Y, Hara M, Yamoto M, Maruyama K, Yasui T.   +5 more
europepmc   +1 more source

Does heart rate variability reflect the systemic inflammatory response in a fetal sheep model of lipopolysaccharide-induced sepsis?

Physiological Measurement, 2015
L. D. Durosier, C. Herry, M. Cortes, M. Cao, P. Burns, A. Desrochers, G. Fecteau, A. Seely, Martin G Frasch   +8 more
semanticscholar   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Valve replacement during pregnancy: literature review including new data from the Registry Of Pregnancy And Cardiac disease III. [PDF]

Eur J Cardiothorac Surg
van der Zande JA, Siromakha S, Peters PNJ, Youssef G, Galian-Gay L, Ladouceur M, Wells G, Takkenberg JJM, Veen KM, Ramlakhan KP, Hall R, Johnson MR, Roos-Hesselink JW, ROPAC Investigators .   +13 more
europepmc   +1 more source

Third Trimester Fetal Heart Rate Predicts Phenotype and Mutation Burden in the Type 1 Long QT Syndrome

Circulation: Arrhythmia and Electrophysiology, 2015
A. Winbo, I. Fosdal, M. Lindh, Ulla-Britt Diamant, Johan Persson, G. Wettrell, A. Rydberg   +6 more
semanticscholar   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Topoisomerase I Inhibition in ETV4‐overexpressed Non‐Small Cell Lung Cancer Promotes Replication and Transcription Mediated R‐Loop Accumulation and DNA Damage

Advanced Science, EarlyView.
The oncogenic ETS factor ETV4 exerts a pleiotropic control over DNA replication both in a transcription‐dependent and ‐independent fashion in NSCLC cells. High‐ETV4 expression leads to R‐loop formation and DNA damage in response to TOP1 inhibition.
Jiaxi Zhang, Yan Wang, Shanhu Cao, Shelly M. Xie, Bei Liu, Yimeng Li, Yuqi Hou, Xue Meng, Mingzhu Ruan, Di Bu, Jia Kang, Ruxin Li, Lei Lou, Juan Wang, Lingxiao Xing   +14 more
wiley   +1 more source