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Pathogenesis and virulence of Heartland virus [PDF]

open access: goldVirulence
Heartland virus (HRTV), an emerging tick-borne pathogenic bunyavirus, has been a concern since 2012, with an increasing incidence, expanding geographical distribution, and high pathogenicity in the United States.
Kuan Feng   +6 more
doaj   +6 more sources

Seroprevalence of Heartland Virus Antibodies in Blood Donors, Northwestern Missouri, USA [PDF]

open access: diamondEmerging Infectious Diseases, 2019
We estimated the seroprevalence of Heartland virus antibodies to be 0.9% (95% CI 0.4%–4.2%) in a convenience sample of blood donors from northwestern Missouri, USA, where human cases and infected ticks have been identified.
Nicole P. Lindsey   +9 more
doaj   +6 more sources

Heartland Virus Disease—An Underreported Emerging Infection [PDF]

open access: yesMicroorganisms
First recognized 15 years ago, Heartland virus disease (Heartland) is a tickborne infection contracted from the transmission of Heartland virus (HRTV) through tick bites from the lone star tick (Amblyomma americanum) and potentially other tick species ...
Zygmunt F. Dembek   +3 more
doaj   +4 more sources

Vertebrate Host Susceptibility to Heartland Virus [PDF]

open access: yesEmerging Infectious Diseases, 2016
Heartland virus (HRTV) is a recently described phlebovirus initially isolated in 2009 from 2 humans who had leukopenia and thrombocytopenia. Serologic assessment of domestic and wild animal populations near the residence of 1 of these persons showed high
Angela M. Bosco-Lauth   +8 more
doaj   +5 more sources

Isolation of Heartland Virus from Lone Star Ticks, Georgia, USA, 2019 [PDF]

open access: yesEmerging Infectious Diseases, 2022
Report of a human death and exposure of white-tailed deer to Heartland virus (HRTV) in Georgia, USA, prompted the sampling of questing ticks during 2018–2019 in 26 sites near where seropositive deer were captured and the residence of the human case ...
Yamila Romer   +8 more
doaj   +4 more sources

Heartland Virus: An Evolving Story of an Emerging Zoonotic and Vector-Borne Disease [PDF]

open access: diamondZoonotic Diseases, 2023
Heartland virus (HRTV) is an emerging tick-borne bandavirus that is capable of causing severe disease characterized by acute thrombocytopenia and lymphopenia.
Emily K. Mantlo, Nicholas J. Haley
doaj   +5 more sources

Heartland Virus Neutralizing Antibodies in Vertebrate Wildlife, United States, 2009–2014 [PDF]

open access: yesEmerging Infectious Diseases, 2015
Since its discovery in 2009, the tickborne Heartland virus (HRTV) has caused human illness in Missouri, Oklahoma, and Tennessee USA. To better assess the geographic distribution of HRTV, we used wildlife serology as an indicator.
Kasen K. Riemersma, Nicholas Komar
doaj   +5 more sources

Heartland virus-associated death in tennessee. [PDF]

open access: hybridClin Infect Dis, 2014
Heartland virus (HRTV) is a tick-borne phlebovirus recently described in Missouri that is associated with fever, leukopenia, and thrombocytopenia. The virus has also been detected in Ambylomma americanum ticks.Here we report the first fatal case of HRTV disease in an 80-year-old Tennessee resident. He was hospitalized with fever, confusion, leukopenia,
Muehlenbachs A   +10 more
europepmc   +5 more sources

Pathological and virological findings of type I interferon receptor knockout mice upon experimental infection with Heartland virus [PDF]

open access: yesVirus Research
Heartland virus (HRTV) causes generalized symptoms, severe shock, and multiple organ failure. We previously reported that interferon-α/β receptor knockout (IFNAR-/-) mice infected intraperitoneally with 1 × 107 tissue culture-infective dose (TCID50) of ...
Hikaru Fujii   +18 more
doaj   +4 more sources

Secondary hemophagocytic lymphohistiocytosis due to Heartland virus. [PDF]

open access: greenBMJ Case Rep, 2022
An older man from the mid-Southeastern USA presented with acute onset of fever, fatigue, and non-bloody diarrhoea. There was high suspicion for tick-borne illness given exposure history, clinical presentation and laboratory abnormalities. Despite prompt treatment with doxycycline, the patient clinically worsened.
Ahlers CG   +3 more
europepmc   +5 more sources

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