Seroprevalence of Heartland Virus Antibodies in Blood Donors, Northwestern Missouri, USA [PDF]
We estimated the seroprevalence of Heartland virus antibodies to be 0.9% (95% CI 0.4%–4.2%) in a convenience sample of blood donors from northwestern Missouri, USA, where human cases and infected ticks have been identified.
Nicole P. Lindsey+9 more
doaj +7 more sources
Heartland Virus Infection in Elderly Patient Initially Suspected of Having Ehrlichiosis, North Carolina, USA [PDF]
We report a patient in North Carolina, USA, with Heartland virus infection whose diagnosis was complicated by previous Ehrlichia chaffeensis infection. We identified E.
Alexis M. Barbarin+6 more
doaj +6 more sources
Vertebrate Host Susceptibility to Heartland Virus [PDF]
Heartland virus (HRTV) is a recently described phlebovirus initially isolated in 2009 from 2 humans who had leukopenia and thrombocytopenia. Serologic assessment of domestic and wild animal populations near the residence of 1 of these persons showed high
Angela M. Bosco-Lauth+8 more
doaj +7 more sources
A novel tick-borne phlebovirus, closely related to severe fever with thrombocytopenia syndrome virus and Heartland virus, is a potential pathogen [PDF]
Tick-borne viral diseases have attracted much attention in recent years because of their increasing incidence and threat to human health. Severe fever with thrombocytopenia syndrome phlebovirus (SFTSV) and Heartland virus (HRTV) were recently identified ...
Shu Shen, Dan Liu, Hualin Wang
exaly +8 more sources
Heartland Virus-Associated Death in Tennessee [PDF]
BACKGROUND Heartland virus (HRTV) is a tick-borne phlebovirus recently described in Missouri that is associated with fever, leukopenia, and thrombocytopenia. The virus has also been detected in Ambylomma americanum ticks.
Christopher D Paddock, Sherif R Zaki
exaly +7 more sources
Heartland Virus: An Evolving Story of an Emerging Zoonotic and Vector-Borne Disease [PDF]
Heartland virus (HRTV) is an emerging tick-borne bandavirus that is capable of causing severe disease characterized by acute thrombocytopenia and lymphopenia.
Emily K. Mantlo, Nicholas J. Haley
doaj +5 more sources
Heartland Virus Neutralizing Antibodies in Vertebrate Wildlife, United States, 2009–2014 [PDF]
Since its discovery in 2009, the tickborne Heartland virus (HRTV) has caused human illness in Missouri, Oklahoma, and Tennessee USA. To better assess the geographic distribution of HRTV, we used wildlife serology as an indicator.
Kasen K. Riemersma, Nicholas Komar
doaj +8 more sources
Safety, Immunogenicity, and Efficacy of a Recombinant Vesicular Stomatitis Virus Vectored Vaccine Against Severe Fever with Thrombocytopenia Syndrome Virus and Heartland Bandavirus [PDF]
Background: Severe fever with thrombocytopenia syndrome virus (SFTSV) is a recently emerged tickborne virus in east Asia with over 18,000 confirmed cases.
Philip Hicks+6 more
doaj +7 more sources
Pathological and virological findings of type I interferon receptor knockout mice upon experimental infection with Heartland virus [PDF]
Heartland virus (HRTV) causes generalized symptoms, severe shock, and multiple organ failure. We previously reported that interferon-α/β receptor knockout (IFNAR-/-) mice infected intraperitoneally with 1 × 107 tissue culture-infective dose (TCID50) of ...
Hikaru Fujii+18 more
doaj +4 more sources
Investigation of Heartland Virus Disease Throughout the United States, 2013-2017. [PDF]
Background Heartland virus (HRTV) was first described as a human pathogen in 2012. From 2013 to 2017, the Centers for Disease Control and Prevention (CDC) implemented a national protocol to evaluate patients for HRTV disease, better define its geographic
Staples JE+8 more
europepmc +6 more sources